Memphramegog only Enrichment analysis PathfindR
Emily Curd
2024-03-22
Enrichment Analysis
This analysis uses the R package: pathfindR: An R Package for Enrichment Analysis Utilizing Active Subnetworks.
citation: Ulgen E, Ozisik O, Sezerman OU. 2019. pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks. Front. Genet. https://doi.org/10.3389/fgene.2019.00858
The aim of PathfindR is to exploit interaction information to extract the most relevant pathways for enrichment analysis. This pathway analysis method identifies genes that are active in sub networks (known to be interconnected) of a given protein-protein interaction network (PIN). It then performs enrichment analysis for each active sub network. The identified pathways are then clustered for functionality to reduce the complexity of the analysis. The overall activity of each pathway is scored and activity per sample can be estimated.
PathfindR integrates information from differential expression/methylation, PIN via active subnetwork identification, and pathway/gene set annotation to identity the of the mechanisms driving a phenotype.
This differs from commonly used over representation analysis and functional class scoring methods, which consider the number of genes identified in a gene list and do not take into account interaction information. They typically also ignore fold changes of p-values.
Analysis Steps (Summarizing the paper and github repo)
Input and format the dataset
- The input data is
- gene symbols
- e.g., Gene_symbol
- if a gene symbol is not in the chosen protein-protein interaction network (PIN), it is converted to an alias symbol if there is an appropriate alias symbol in the PIN
- change values (optional)
- e.g., logFC
- associated p-values
- e.g., adjPval
- gene symbols
Map the statistical significance of each gene onto a PIN
- Input genes with associated p-values are mapped on to the PIN.
- The mapped hits are used to search for active subnetworks.
- An active subnetwork is a subnetwork in the PIN containing an optimal number of significant nodes that maximizes the overall significance of the subnetwork
- Active subnetworks have genes/proteins in direct contact or in indirect contact via a non-input node
- Three algorithms implemented in the pathfindR package for active
subnetwork search (see paper for details):
- Greedy algorithm (default - tends to result in multiple active subnetworks)
- Simulated annealing algorithm (tends to choose the single highest scoring active subnetwork)
- Genetic Algorithm (tends to choose the single highest scoring active subnetwork)
Filter the subnetwork
- The identified active subnetworks are filtered by scores and numbers
of significant genes.
- has a score larger than the given quantile threshold (default is 0.80)
- contains at least a specified number of input genes (default is 10).
Run the enrichment analyses on active subnetworks
- Enrichment analysis is run on filtered lists of active subnetworks.
- Enrichment is performed via one-sided hypergeometric testing
- enrichment tests use only the genes in the PIN as background genes.
- significantly enriched terms are identified using the genes the
active subnetworks
- enriched terms = pathways or gene sets
- Enriched terms are discarded if they have an adjusted p-values (default-Bonferroni method) > a given threshold are discarded
- The lowest lowest adjusted p-value for a term is kept (across all active subnetworks).
- Enrichment is run for n iterations in parallel.
- for each significantly enriched term, the lowest and the highest adjusted p-values, and the number of occurrences across iterations are reported.
- Enrichment is performed via one-sided hypergeometric testing
- Pathway clustering
- Enrichment analysis usually recovers many related pathways.
- pathways are clustered (describes in the paper)
- hierarchical clustering (default)
- fuzzy clustering method
- pathways are clustered (describes in the paper)
- Enrichment analysis usually recovers many related pathways.
- Pathway scoring
- a pathway score matrix is calculated for each sample.
- Scores can be plotted as a heat map
Avalible PINs:
“Biogrid”, “STRING”, “GeneMania”, “IntAct”, “KEGG” and “mmu_STRING”, custom
###The available gene sets: “KEGG”, “Reactome”, “BioCarta”, “GO-All”, “GO-BP”, “GO-CC”, “GO-MF”, and “mmu_KEGG”, custom
Output columns
Fold Enrichment: Fold enrichment value for the enriched term (Calculated using ONLY the input genes). This is calculated as the proportion of pathway genes within all INPUT (not subnetwork) genes over the proportion pathway genes within the background genes. For example, if the proportion of pathway genes in the input is 0.5 and the proportion of pathway genes in the background is 0.25, the fold enrichment value is 2. The background genes in pathfindR is used as all the genes in the protein-protein interaction network.
occurence: the number of iterations that the given term was found to enriched over all iterations (as the active subnetwork search + enrichment processes are run for multiple (by default 10) iterations)
support: the median support (proportion of active subnetworks leading to enrichment within an iteration) over all iterations. This reflects how many subnetworks support the enrichment
lowest and highest p values: these are the lowest and highest adjusted-p values of enrichment observed over all iterations
Running PathfindR
Load libraries - silent loading
suppressPackageStartupMessages({
library(tibble)
library(plyr)
#library(RColorBrewer)
#library(pheatmap)
#library(ggfortify)
#library(DEqMS)
library(readxl)
library(tidyr)
library(dplyr)
#library(ggplot2)
#library(fgsea)
#library(RforProteomics)
#library(ggrepel)
library(pathfindR)
})Set objects
This chunk is only important if… you have abundance data - and its human
# sample names - should match columns in file
Col_list <- c("m_n_vt2_10","m_n_vt2_14","m_n_vt2_16","m_n_vt2_18","m_n_vt2_23","m_t_vt2_02","m_t_vt2_05","m_t_vt2_06","m_t_vt2_28","m_t_vt2_29R","m_t_vt2_30","m_t_vt2_32","m_t_vt2_37","m_t_vt2_40")
# group identity for samples in Col_list
grp <- c("n","n","n","n","n", "t","t","t","t","t","t","t","t","t" )
# treatment group
cases <- c("m_t_vt2_02","m_t_vt2_05","m_t_vt2_06","m_t_vt2_28","m_t_vt2_29R","m_t_vt2_30","m_t_vt2_32","m_t_vt2_37","m_t_vt2_40")#path to file
file <- "/Users/eguswa/Documents/R_markdown_with_expalinations/RNAseq/Bullhead_rnaseq/Just_memph/pathfindR/pathfinder_input.xlsx"
#path for output - will make directory in location of R project - or where specified
outdir <- "/Users/eguswa/Documents/R_markdown_with_expalinations/RNAseq/Bullhead_rnaseq/Just_memph/pathfindR/"
# protein interaction network to run on the pathfindR differentially expressed protein dataset using the Protein Interaction Network (pin) of your choice:
# "Biogrid", "STRING", "GeneMania", "IntAct", "KEGG", "mmu_STRING"
pin <- "KEGG"
gene_sets = "KEGG"
# adjustment methods for pathfindF() pathway enrichment - options:
# “holm”, “hochberg”, “hommel”, “bonferroni”, “BH”, “BY”, “fdr”, “none”"
# default is bonferroni
adj_method = "bonferroni"
# enrichment threshold options for pathfindF() pathway enrichment:
# adjusted-p value threshold used when filtering enrichment results (default = 0.05)
enrichment_threshold = 0.05
# several more options to play with
# number of terms to show in first enrichment plot - will add more options for later plots
top_terms <- 15Load files and make dataframes.
The minimum requirement is that there is a column named Gene_Symbol and a column named P.value
#make outdir
dir.create(outdir, recursive = TRUE)## Warning in dir.create(outdir, recursive = TRUE):
## '/Users/eguswa/Documents/R_markdown_with_expalinations/RNAseq/Bullhead_rnaseq/Just_memph/pathfindR'
## already existsdf.prot <- read_excel(file)
#if have abundance data
dat <- df.prot %>% arrange((P.val)) %>% group_by(Gene_Symbol) %>% slice_head() %>% ungroup() %>% select(Gene_Symbol, all_of(Col_list)) %>% drop_na() %>% column_to_rownames("Gene_Symbol")
datPF <- df.prot %>% select(Gene_Symbol, logFC, P.val) %>% arrange(P.val) %>% group_by(Gene_Symbol) %>% slice_head() %>% drop_na() %>% ungroup()
datPF <- as.data.frame(datPF)Convert the pathfindR Kegg gene database to a dataframe.
All PIN use Kegg gene database, b/c it is the default. The dataframe is used to add list of all genes in a pathway to the results table.
kegg <- plyr::ldply(pathfindR.data::kegg_genes, data.frame) %>% mutate(num_genes_in_path = 1) %>% dplyr::group_by(.data$.id) %>% dplyr::summarize(X..i.. = paste0(.data$X..i.., collapse = ", "), num_genes_in_path = sum(num_genes_in_path))
names(kegg)[1] <- "ID"
names(kegg)[2] <- "all_pathway_genes"Run pathfindR
calculate percent of differentially expressed genes in a pathway and add to the results table adjustment methods “holm”, “hochberg”, “hommel”, “bonferroni”, “BH”, “BY”, “fdr”, “none””
- Fold Enrichment = percentage of genes in your list belonging to a pathway, divided by the corresponding percentage in the background PIN
output_df_pin <- run_pathfindR(datPF, pin_name_path = pin,
adj_method = adj_method,
enrichment_threshold = enrichment_threshold,
iterations = 25, list_active_snw_genes=TRUE)## ## Testing input## The input looks OK## ## Processing input. Converting gene symbols,
## if necessary (and if human gene symbols provided)## Number of genes provided in input: 10881## Number of genes in input after p-value filtering: 10881## pathfindR cannot handle p values < 1e-13. These were changed to 1e-13## ## Could not find any interactions for 9746 (89.57%) genes in the PIN## Final number of genes in input: 1135## ## Performing Active Subnetwork Search and Enrichment## ## Processing the enrichment results over all iterations## ## Annotating involved genes and visualizing enriched terms## Plotting the enrichment bubble chart## Found 168 enriched terms## You may run:## - cluster_enriched_terms() for clustering enriched terms## - visualize_terms() for visualizing enriched term diagrams
output_df_pin <- left_join(output_df_pin, kegg)## Joining with `by = join_by(ID)`output_df_pin <- output_df_pin %>%
mutate(num_up_reg_genes_in_path = 1+lengths(regmatches(Up_regulated, gregexpr(",",Up_regulated )))) %>%
mutate(num_down_reg_genes_in_path = 1+lengths(regmatches(Down_regulated, gregexpr(",",Down_regulated )))) %>%
mutate(percent_up_or_down_genes_pathway = ((num_up_reg_genes_in_path + num_down_reg_genes_in_path) / num_genes_in_path))Visualize differentially expressed genes in Enriched pathways.
KEGG gives nice figures - might not reflect interactions as well as the others, other pins give networks of stuff - might be more concise
if (pin == "KEGG"){
print(paste0("Visualizing ", pin))
processed_df <- input_processing(
input = datPF,
pin_name_path = pin
)
visualize_terms(
result_df=output_df_pin,
input_processed=processed_df,
hsa_KEGG = FALSE #TRUE if human
)
} else {
print(paste0("Visualizing ", pin))
visualize_terms(
result_df=output_df_pin,
input_processed=processed_df,
hsa_KEGG=FALSE,
pin_name_path=pin
)
}
old_folder_name <- "term_visualizations"
new_folder_name <- paste0(outdir,"/", pin,"_term_visualizations")
file.rename(old_folder_name, new_folder_name) Generate enrichment chart using the top_terms specified by user.
#
pdf(file = paste0(outdir,"/Enrichment_with_", pin, "_top_", top_terms, "_terms.pdf"))
enrichment_chart(
result_df = output_df_pin,
top_terms = top_terms
)## Plotting the enrichment bubble chartdev.off()## quartz_off_screen
## 2enrichment_chart(
result_df = output_df_pin,
top_terms = top_terms
)## Plotting the enrichment bubble chart
Cluster enriched terms using defult method.
pdf(file=(paste0(outdir,"/Enrichment_cluster_", pin,".pdf")))
cluster_enriched_terms(output_df_pin, plot_dend = TRUE, plot_clusters_graph = TRUE)## The maximum average silhouette width was 0.14 for k = 60## ID Term_Description
## 1 hsa05012 Parkinson disease
## 2 hsa05020 Prion disease
## 8 hsa04932 Non-alcoholic fatty liver disease
## 9 hsa04723 Retrograde endocannabinoid signaling
## 12 hsa04714 Thermogenesis
## 14 hsa00190 Oxidative phosphorylation
## 18 hsa05415 Diabetic cardiomyopathy
## 21 hsa05208 Chemical carcinogenesis - reactive oxygen species
## 3 hsa04068 FoxO signaling pathway
## 4 hsa03050 Proteasome
## 15 hsa05017 Spinocerebellar ataxia
## 5 hsa04110 Cell cycle
## 7 hsa04114 Oocyte meiosis
## 11 hsa04914 Progesterone-mediated oocyte maturation
## 24 hsa04120 Ubiquitin mediated proteolysis
## 6 hsa04115 p53 signaling pathway
## 10 hsa00562 Inositol phosphate metabolism
## 13 hsa04070 Phosphatidylinositol signaling system
## 16 hsa00230 Purine metabolism
## 23 hsa00240 Pyrimidine metabolism
## 17 hsa04630 JAK-STAT signaling pathway
## 19 hsa04014 Ras signaling pathway
## 39 hsa04010 MAPK signaling pathway
## 58 hsa04015 Rap1 signaling pathway
## 20 hsa04211 Longevity regulating pathway
## 25 hsa04931 Insulin resistance
## 27 hsa04152 AMPK signaling pathway
## 29 hsa04922 Glucagon signaling pathway
## 46 hsa04910 Insulin signaling pathway
## 47 hsa04213 Longevity regulating pathway - multiple species
## 61 hsa04936 Alcoholic liver disease
## 71 hsa04920 Adipocytokine signaling pathway
## 22 hsa05166 Human T-cell leukemia virus 1 infection
## 65 hsa05203 Viral carcinogenesis
## 26 hsa03320 PPAR signaling pathway
## 147 hsa00071 Fatty acid degradation
## 28 hsa05132 Salmonella infection
## 49 hsa05131 Shigellosis
## 57 hsa05135 Yersinia infection
## 74 hsa05130 Pathogenic Escherichia coli infection
## 30 hsa04668 TNF signaling pathway
## 31 hsa05170 Human immunodeficiency virus 1 infection
## 37 hsa05163 Human cytomegalovirus infection
## 45 hsa04380 Osteoclast differentiation
## 52 hsa05417 Lipid and atherosclerosis
## 73 hsa05167 Kaposi sarcoma-associated herpesvirus infection
## 85 hsa04210 Apoptosis
## 32 hsa04064 NF-kappa B signaling pathway
## 33 hsa04728 Dopaminergic synapse
## 55 hsa04926 Relaxin signaling pathway
## 56 hsa04918 Thyroid hormone synthesis
## 60 hsa04261 Adrenergic signaling in cardiomyocytes
## 64 hsa04935 Growth hormone synthesis, secretion and action
## 68 hsa04911 Insulin secretion
## 76 hsa04725 Cholinergic synapse
## 82 hsa04925 Aldosterone synthesis and secretion
## 95 hsa04928 Parathyroid hormone synthesis, secretion and action
## 101 hsa04915 Estrogen signaling pathway
## 111 hsa04927 Cortisol synthesis and secretion
## 121 hsa04929 GnRH secretion
## 133 hsa04022 cGMP-PKG signaling pathway
## 34 hsa05160 Hepatitis C
## 40 hsa05161 Hepatitis B
## 42 hsa05162 Measles
## 43 hsa05169 Epstein-Barr virus infection
## 53 hsa05222 Small cell lung cancer
## 135 hsa05164 Influenza A
## 35 hsa05142 Chagas disease
## 50 hsa05145 Toxoplasmosis
## 70 hsa04620 Toll-like receptor signaling pathway
## 83 hsa05152 Tuberculosis
## 86 hsa05171 Coronavirus disease - COVID-19
## 99 hsa05140 Leishmaniasis
## 112 hsa05133 Pertussis
## 130 hsa04625 C-type lectin receptor signaling pathway
## 36 hsa04919 Thyroid hormone signaling pathway
## 160 hsa04613 Neutrophil extracellular trap formation
## 38 hsa04722 Neurotrophin signaling pathway
## 63 hsa04912 GnRH signaling pathway
## 98 hsa04750 Inflammatory mediator regulation of TRP channels
## 41 hsa04622 RIG-I-like receptor signaling pathway
## 48 hsa04621 NOD-like receptor signaling pathway
## 54 hsa04657 IL-17 signaling pathway
## 44 hsa00760 Nicotinate and nicotinamide metabolism
## 51 hsa04071 Sphingolipid signaling pathway
## 59 hsa04371 Apelin signaling pathway
## 127 hsa04921 Oxytocin signaling pathway
## 62 hsa05215 Prostate cancer
## 75 hsa04664 Fc epsilon RI signaling pathway
## 79 hsa05212 Pancreatic cancer
## 81 hsa04917 Prolactin signaling pathway
## 89 hsa05223 Non-small cell lung cancer
## 100 hsa04012 ErbB signaling pathway
## 102 hsa04370 VEGF signaling pathway
## 106 hsa05221 Acute myeloid leukemia
## 108 hsa05218 Melanoma
## 113 hsa05220 Chronic myeloid leukemia
## 115 hsa05214 Glioma
## 119 hsa05210 Colorectal cancer
## 128 hsa05231 Choline metabolism in cancer
## 131 hsa05213 Endometrial cancer
## 134 hsa04662 B cell receptor signaling pathway
## 140 hsa05211 Renal cell carcinoma
## 146 hsa04666 Fc gamma R-mediated phagocytosis
## 166 hsa04650 Natural killer cell mediated cytotoxicity
## 66 hsa04062 Chemokine signaling pathway
## 67 hsa04933 AGE-RAGE signaling pathway in diabetic complications
## 69 hsa04810 Regulation of actin cytoskeleton
## 155 hsa04510 Focal adhesion
## 72 hsa05205 Proteoglycans in cancer
## 91 hsa04916 Melanogenesis
## 107 hsa04550 Signaling pathways regulating pluripotency of stem cells
## 109 hsa05224 Breast cancer
## 110 hsa05226 Gastric cancer
## 120 hsa04934 Cushing syndrome
## 150 hsa04150 mTOR signaling pathway
## 154 hsa05225 Hepatocellular carcinoma
## 77 hsa04140 Autophagy - animal
## 78 hsa05207 Chemical carcinogenesis - receptor activation
## 80 hsa05230 Central carbon metabolism in cancer
## 142 hsa04066 HIF-1 signaling pathway
## 163 hsa04973 Carbohydrate digestion and absorption
## 84 hsa04137 Mitophagy - animal
## 87 hsa04218 Cellular senescence
## 88 hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
## 96 hsa04658 Th1 and Th2 cell differentiation
## 103 hsa04660 T cell receptor signaling pathway
## 132 hsa04659 Th17 cell differentiation
## 90 hsa04611 Platelet activation
## 92 hsa05030 Cocaine addiction
## 116 hsa05031 Amphetamine addiction
## 145 hsa05034 Alcoholism
## 93 hsa04924 Renin secretion
## 97 hsa04713 Circadian entrainment
## 122 hsa04724 Glutamatergic synapse
## 124 hsa04720 Long-term potentiation
## 129 hsa04970 Salivary secretion
## 139 hsa04540 Gap junction
## 141 hsa04730 Long-term depression
## 149 hsa04726 Serotonergic synapse
## 151 hsa04971 Gastric acid secretion
## 157 hsa04270 Vascular smooth muscle contraction
## 94 hsa04020 Calcium signaling pathway
## 104 hsa05418 Fluid shear stress and atherosclerosis
## 105 hsa05219 Bladder cancer
## 159 hsa05216 Thyroid cancer
## 114 hsa04217 Necroptosis
## 117 hsa04215 Apoptosis - multiple species
## 118 hsa04072 Phospholipase D signaling pathway
## 123 hsa04530 Tight junction
## 125 hsa04350 TGF-beta signaling pathway
## 126 hsa04144 Endocytosis
## 136 hsa04260 Cardiac muscle contraction
## 137 hsa04360 Axon guidance
## 138 hsa05321 Inflammatory bowel disease
## 143 hsa04710 Circadian rhythm
## 156 hsa05410 Hypertrophic cardiomyopathy
## 144 hsa05120 Epithelial cell signaling in Helicobacter pylori infection
## 152 hsa05110 Vibrio cholerae infection
## 148 hsa04310 Wnt signaling pathway
## 162 hsa04390 Hippo signaling pathway
## 153 hsa04024 cAMP signaling pathway
## 158 hsa04670 Leukocyte transendothelial migration
## 161 hsa04923 Regulation of lipolysis in adipocytes
## 164 hsa03010 Ribosome
## 165 hsa04742 Taste transduction
## 167 hsa04640 Hematopoietic cell lineage
## 168 hsa05202 Transcriptional misregulation in cancer
## Fold_Enrichment occurrence support lowest_p highest_p
## 1 1.8292876 25 0.12500000 1.130801e-55 2.597446e-26
## 2 1.6665847 25 0.23529412 5.761775e-48 4.500346e-27
## 8 1.8241527 25 0.35000000 1.337914e-25 7.455760e-20
## 9 1.2553495 25 0.17647059 1.286070e-24 1.223207e-20
## 12 1.6809404 25 0.15000000 4.176881e-24 8.291980e-18
## 14 1.8300966 25 0.11764706 2.844520e-23 7.028650e-11
## 18 1.3736390 25 0.11764706 1.471073e-19 4.726090e-13
## 21 1.4366965 25 0.18750000 8.861795e-19 2.653957e-12
## 3 1.5463775 25 0.25000000 4.487469e-40 1.171682e-08
## 4 3.0068451 25 0.05882353 1.226020e-33 2.979845e-28
## 15 1.5229475 25 0.06250000 6.013291e-22 4.943673e-18
## 5 2.3743592 1 0.05882353 2.364733e-31 2.364733e-31
## 7 1.3960352 4 0.05882353 1.946968e-26 4.755571e-02
## 11 1.5954688 21 0.06666667 3.846064e-24 3.941275e-04
## 24 1.8378185 1 0.05882353 4.385403e-17 4.385403e-17
## 6 1.8613803 25 0.06250000 1.360411e-27 1.979353e-23
## 10 1.7593869 25 0.11764706 1.633710e-24 5.021936e-19
## 13 1.2665062 25 0.11764706 5.318512e-24 3.863940e-19
## 16 1.0985195 25 0.05882353 8.085171e-22 7.283707e-17
## 23 1.4441744 25 0.05882353 4.279645e-17 3.045741e-10
## 17 0.9082639 25 0.05882353 1.120779e-19 4.485681e-14
## 19 1.0977371 25 0.26666667 1.553767e-19 5.812880e-06
## 39 0.9306902 25 0.41176471 6.369094e-11 3.068439e-08
## 58 0.9885800 25 0.25000000 2.433538e-09 1.034220e-05
## 20 1.3803495 25 0.31250000 2.260584e-19 4.734851e-16
## 25 1.2231928 25 0.25000000 2.531488e-16 3.063640e-13
## 27 1.5690975 25 0.27777778 2.024612e-15 1.781473e-12
## 29 1.3170144 25 0.31578947 1.760017e-13 4.305054e-11
## 46 1.3043249 25 0.18750000 3.466049e-10 1.984007e-08
## 47 1.0069762 25 0.16666667 4.921795e-10 3.654994e-07
## 61 1.3370478 25 0.35294118 5.751423e-09 8.264046e-07
## 71 1.3758028 25 0.23529412 3.803411e-08 1.303700e-04
## 22 1.4820469 25 0.33333333 3.521550e-18 1.411522e-06
## 65 1.1106579 25 0.20000000 1.268391e-08 1.343007e-03
## 26 0.8902254 24 0.05882353 7.774767e-16 1.373159e-13
## 147 1.4981842 22 0.05882353 4.566128e-03 6.364385e-03
## 28 1.4252410 25 0.18750000 1.396258e-13 1.607805e-05
## 49 1.1576878 25 0.26315789 5.626264e-10 4.152155e-07
## 57 1.4781550 25 0.31250000 2.304547e-09 3.360939e-05
## 74 1.0470264 25 0.12500000 2.188487e-07 2.600788e-02
## 30 1.5595349 25 0.47368421 2.510787e-13 1.254879e-10
## 31 1.1966016 25 0.41176471 6.246538e-13 8.924990e-07
## 37 0.9765986 25 0.52941176 3.560833e-11 1.990330e-07
## 45 1.1079645 25 0.31578947 2.661099e-10 4.978435e-06
## 52 1.0272712 25 0.35294118 1.033419e-09 4.432584e-07
## 73 0.9647992 25 0.45000000 2.078783e-07 4.066796e-04
## 85 1.2268188 25 0.21052632 2.401625e-06 9.892376e-04
## 32 1.3960352 25 0.15000000 1.577634e-12 1.816241e-08
## 33 0.9377947 25 0.41176471 1.914453e-12 3.581821e-10
## 55 0.8224704 25 0.40000000 1.990749e-09 3.307867e-07
## 56 1.0675564 25 0.17647059 2.007248e-09 9.442942e-08
## 60 0.7870266 25 0.23529412 3.994682e-09 7.993436e-07
## 64 0.9772247 25 0.40000000 1.250515e-08 3.695029e-07
## 68 0.7883493 25 0.16666667 2.296463e-08 1.793329e-05
## 76 0.8272801 25 0.31250000 1.005231e-06 3.955496e-04
## 82 0.6465847 25 0.22222222 1.438358e-06 3.898911e-05
## 95 0.8590986 25 0.26315789 8.375171e-06 1.966384e-04
## 101 0.6618241 25 0.31250000 1.701086e-05 3.319780e-03
## 111 0.9907347 25 0.17647059 6.827192e-05 1.797891e-04
## 121 1.0069762 24 0.10263158 2.111184e-04 4.822899e-02
## 133 0.8409851 25 0.23529412 7.542031e-04 1.375335e-02
## 34 1.1603410 25 0.23529412 2.898629e-12 2.154751e-09
## 40 1.2913326 25 0.41176471 6.529909e-11 9.323482e-08
## 42 1.3043249 25 0.33333333 1.244494e-10 4.724475e-08
## 43 1.4311115 25 0.40000000 2.334021e-10 2.252560e-07
## 53 1.6752423 25 0.22222222 1.491552e-09 1.919109e-07
## 135 0.9489390 25 0.11764706 7.715880e-04 1.363069e-02
## 35 1.1057705 25 0.36842105 1.158728e-11 1.568350e-07
## 50 1.0061515 25 0.29411765 5.688601e-10 1.273192e-06
## 70 1.0401831 25 0.29411765 3.656631e-08 1.967112e-05
## 83 0.8566580 25 0.17647059 1.770374e-06 9.244502e-04
## 86 1.0224483 25 0.25000000 3.312677e-06 2.302805e-04
## 99 0.7546136 25 0.17647059 1.343760e-05 3.486242e-04
## 112 0.9055364 25 0.18750000 7.357469e-05 9.331531e-03
## 130 1.0738733 25 0.35294118 4.621091e-04 3.468165e-03
## 36 1.1168282 24 0.05882353 2.771517e-11 2.121381e-09
## 160 0.6940740 5 0.05882353 1.972297e-02 3.795391e-02
## 38 0.9937878 25 0.41176471 3.705729e-11 1.092164e-04
## 63 0.8406234 25 0.21052632 7.268666e-09 3.909257e-06
## 98 0.9711550 25 0.25000000 9.836259e-06 1.060639e-04
## 41 1.3758028 25 0.23529412 9.422708e-11 1.971503e-07
## 48 0.9651602 25 0.22222222 5.336650e-10 3.265924e-07
## 54 1.3353381 25 0.22222222 1.869154e-09 2.042866e-06
## 44 1.1168282 25 0.05882353 2.366418e-10 8.281689e-10
## 51 1.5485433 25 0.35294118 8.113162e-10 2.646628e-07
## 59 1.0116197 25 0.35294118 3.275017e-09 2.477557e-06
## 127 0.6569578 25 0.17647059 3.536775e-04 1.695507e-03
## 62 1.0808015 25 0.22222222 5.989213e-09 1.414845e-05
## 75 1.1845148 24 0.13750000 9.034852e-07 3.602977e-02
## 79 1.3225597 25 0.31250000 1.138140e-06 8.640217e-05
## 81 1.1966016 25 0.41176471 1.377611e-06 1.305015e-03
## 89 0.9572813 25 0.12500000 4.550874e-06 4.535192e-02
## 100 0.9971680 25 0.15000000 1.650468e-05 7.287659e-03
## 102 1.1357575 18 0.10526316 1.856566e-05 3.171483e-02
## 106 1.1668354 25 0.17647059 3.266202e-05 7.364733e-04
## 108 0.9306902 25 0.11764706 5.414650e-05 3.420203e-03
## 113 1.1021331 25 0.25000000 7.898224e-05 2.993283e-03
## 115 0.8934626 24 0.10263158 7.977649e-05 3.023976e-02
## 119 0.8073457 22 0.08333333 1.466323e-04 3.817356e-02
## 128 0.7977344 11 0.05555556 3.941275e-04 8.406676e-03
## 131 0.6739480 24 0.06666667 6.272380e-04 3.435759e-02
## 134 1.0738733 19 0.05882353 7.612100e-04 4.626387e-02
## 140 0.7501085 20 0.06250000 1.292464e-03 4.480615e-02
## 146 1.0470264 2 0.05882353 2.036799e-03 1.252730e-02
## 166 0.6107654 3 0.05263158 3.036627e-02 3.734760e-02
## 66 0.9992673 22 0.10000000 1.274669e-08 2.928906e-02
## 67 1.2285110 25 0.50000000 1.415977e-08 6.974854e-06
## 69 0.9796739 24 0.12500000 3.332444e-08 3.470163e-02
## 155 0.8376211 15 0.05882353 9.639126e-03 2.784437e-02
## 72 0.9806296 25 0.15000000 1.949856e-07 6.751522e-05
## 91 0.7740393 25 0.11764706 7.549080e-06 3.090807e-04
## 107 1.1830807 25 0.13333333 4.314888e-05 7.202468e-04
## 109 1.2155953 25 0.15789474 6.156305e-05 3.117129e-03
## 110 0.9876712 18 0.06066176 6.156305e-05 4.097376e-02
## 120 1.2073818 25 0.31578947 1.498384e-04 3.259538e-03
## 150 1.3329885 21 0.06666667 5.681658e-03 4.637371e-02
## 154 1.2037669 12 0.06250000 8.782227e-03 4.098889e-02
## 77 1.6353556 25 0.31250000 1.012823e-06 1.621949e-05
## 78 0.9533899 25 0.17647059 1.065990e-06 7.674247e-05
## 80 0.9711550 21 0.06250000 1.242789e-06 4.287423e-02
## 142 0.8709211 25 0.06250000 1.556261e-03 2.564212e-02
## 163 1.0152984 7 0.05555556 2.520486e-02 3.169241e-02
## 84 1.8347892 6 0.05263158 1.896690e-06 3.443134e-06
## 87 1.3690152 25 0.29411765 3.351024e-06 1.947287e-03
## 88 1.1293768 25 0.25000000 3.880494e-06 4.729457e-04
## 96 1.1045554 25 0.11764706 8.849872e-06 2.696910e-03
## 103 1.1927291 25 0.29411765 2.105540e-05 5.288261e-04
## 132 0.7828235 25 0.11111111 6.618637e-04 2.819041e-02
## 90 1.2711866 25 0.11764706 5.516379e-06 1.275341e-02
## 92 0.7977344 25 0.23529412 7.724285e-06 3.318136e-04
## 116 0.6474366 25 0.17647059 8.104571e-05 4.008433e-03
## 145 0.6551227 25 0.10526316 1.898447e-03 2.816594e-02
## 93 1.0999066 25 0.05882353 8.229217e-06 4.057520e-04
## 97 0.6332531 25 0.12500000 9.211802e-06 3.904460e-03
## 122 0.3948383 23 0.06666667 2.184690e-04 4.411531e-02
## 124 0.7501085 25 0.13333333 2.540634e-04 6.035296e-03
## 129 0.6884557 25 0.05882353 4.242714e-04 1.370363e-02
## 139 0.7614738 24 0.05882353 1.280787e-03 3.368011e-02
## 141 0.6739480 25 0.11764706 1.410352e-03 3.288938e-03
## 149 0.6443240 21 0.10000000 4.896791e-03 4.786507e-02
## 151 0.4927183 20 0.05882353 6.169115e-03 1.117203e-02
## 157 0.5834177 18 0.05882353 1.730845e-02 2.889468e-02
## 94 0.8609909 25 0.11764706 8.339534e-06 8.110897e-04
## 104 1.2453840 25 0.37500000 2.939269e-05 3.090506e-04
## 105 0.9772247 25 0.05882353 3.185702e-05 4.400582e-02
## 159 0.7546136 9 0.05882353 1.971132e-02 4.983832e-02
## 114 0.9189093 25 0.05882353 7.956339e-05 1.249709e-03
## 117 1.4891043 25 0.06250000 8.174833e-05 7.566453e-03
## 118 0.7217597 19 0.06250000 8.231501e-05 3.460479e-02
## 123 1.0636459 25 0.16666667 2.298507e-04 2.422987e-03
## 125 1.2139437 24 0.05882353 2.953783e-04 7.422386e-03
## 126 0.9948757 22 0.05882353 3.004276e-04 1.096662e-02
## 136 0.7583401 17 0.05555556 7.862696e-04 1.689134e-02
## 137 0.8765803 18 0.05882353 9.554870e-04 2.111165e-02
## 138 0.6980176 17 0.05882353 1.028094e-03 4.363570e-02
## 143 1.8613803 25 0.21052632 1.574741e-03 3.575034e-03
## 156 0.7400669 12 0.05882353 1.040339e-02 2.284557e-02
## 144 0.8775079 24 0.10263158 1.607557e-03 4.535192e-02
## 152 0.6493187 5 0.05882353 6.558405e-03 1.386227e-02
## 148 1.1034530 20 0.05882353 4.698828e-03 1.066262e-02
## 162 1.0670333 8 0.05882353 2.384586e-02 4.976264e-02
## 153 0.6001647 16 0.05882353 8.041354e-03 4.682689e-02
## 158 0.5878043 6 0.05882353 1.745498e-02 4.539073e-02
## 161 0.8665046 1 0.05555556 2.166577e-02 2.166577e-02
## 164 2.7920705 6 0.05263158 2.791943e-02 3.265196e-02
## 165 0.7977344 20 0.05882353 3.027273e-02 4.847475e-02
## 167 0.9627829 1 0.05882353 3.663914e-02 3.663914e-02
## 168 0.8334539 3 0.06666667 3.955734e-02 4.638489e-02
## non_Signif_Snw_Genes
## 1 SOD1
## 2 SOD1
## 8
## 9 PRKACG
## 12 PRKACG
## 14
## 18
## 21
## 3
## 4
## 15
## 5 ANAPC5
## 7 MAPK1
## 11 KRAS
## 24 ANAPC5
## 6 TP53
## 10 PLCB3
## 13 PLCB3
## 16 ENPP1
## 23 ENPP1
## 17 STAT1
## 19 KRAS
## 39 KRAS
## 58 KRAS
## 20 ATF2
## 25
## 27
## 29 PRKACG
## 46
## 47
## 61
## 71
## 22 FOS
## 65
## 26 RXRA
## 147
## 28 RAC1
## 49
## 57 RAC1
## 74 RAC1
## 30
## 31 RAC1
## 37 ATF2
## 45 RAC1
## 52
## 73 KRAS
## 85
## 32
## 33 PRKCB
## 55
## 56 PRKCB
## 60 ATF2
## 64 PRKCB
## 68 PRKCB
## 76 PRKCB
## 82 PRKCB
## 95 PRKCB
## 101 ATF2
## 111
## 121 KRAS
## 133 PLCB3
## 34 STAT1
## 40 ATF2
## 42 FOS
## 43
## 53
## 135 STAT1
## 35
## 50
## 70 RAC1
## 83
## 86 FOS
## 99 FOS
## 112 FOS
## 130 KRAS
## 36 RXRA
## 160 RAC1
## 38 KRAS
## 63 KRAS
## 98 PRKCB
## 41
## 48
## 54
## 44 ENPP1
## 51
## 59 PRKACG
## 127 PRKACG
## 62
## 75 KRAS
## 79
## 81 FOS
## 89 MAPK1
## 100 KRAS
## 102 KRAS
## 106 MAPK1
## 108 MAPK1
## 113
## 115 KRAS
## 119 KRAS
## 128 KRAS
## 131 KRAS
## 134 MAPK1
## 140 KRAS
## 146 MAPK1
## 166 KRAS
## 66 KRAS
## 67
## 69 RAC1
## 155
## 72 MAPK1
## 91 PLCB3
## 107 KRAS
## 109
## 110 EGFR
## 120 PLCB3
## 150
## 154
## 77
## 78 ATF2
## 80 KRAS
## 142
## 163 PLCB3
## 84
## 87
## 88 FOS
## 96 FOS
## 103 MAPK1
## 132 FOS
## 90 PLCB3
## 92 ATF2
## 116 FOS
## 145 PRKACG
## 93 PLCB3
## 97 PLCB3
## 122 PLCB3
## 124 PLCB3
## 129 PLCB3
## 139 PLCB3
## 141 PRKCB
## 149 KRAS
## 151 PLCB3
## 157
## 94 PLCB3
## 104
## 105 MAPK1
## 159 MAPK1
## 114 STAT1
## 117
## 118 PLCB3
## 123
## 125 MAPK1
## 126 EGFR
## 136
## 137 RAC1
## 138
## 143
## 156
## 144 RAC1
## 152
## 148 PLCB3
## 162
## 153 PRKACG
## 158 RAC1
## 161 GNAI3
## 164
## 165 PLCB3
## 167
## 168
## Up_regulated
## 1 ADORA2A, PSMA5, PSMA1, PSMA3, PSMB6, PSMB3, PSMB5, PSMB1, PSMB4, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD3, PSMD9, PSMD11, PSMD6, PSMD7, HSPA5, DDIT3, EIF2S1, SLC18A1, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, NDUFS3, NDUFS4, NDUFS6, NDUFS8, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, ATP5PD, LRRK2, HTRA2, PARK7, BCL2L1, KLC2, TUBB3, TUBB4A, DUSP1, NFE2L2, MAPK9
## 2 STIP1, HSPA5, EIF2S1, DDIT3, PPP3CB, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, NDUFS3, NDUFS4, NDUFS6, NDUFS8, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, ATP5PD, PSMA5, PSMA1, PSMA3, PSMB6, PSMB3, PSMB5, PSMB1, PSMB4, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD3, PSMD9, PSMD11, PSMD6, PSMD7, CAV1, PIK3CB, MAPK9, CREB5, EGR1, CSNK2B, KLC2, TUBB3, TUBB4A
## 8 SOCS3, PIK3CB, GSK3A, ADIPOR1, PRKAA1, PRKAA2, PRKAG1, PRKAG3, MAPK9, TRAF2, EIF2S1, DDIT3, CASP7, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, NDUFS3, NDUFS4, NDUFS6, NDUFS8, UQCRC1, UQCR10, COX6A1, COX6C, COX8A
## 9 KCNJ5, MAPK9, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, NDUFS3, NDUFS4, NDUFS6, NDUFS8
## 12 CREB5, SMARCC2, SMARCD1, ACTL6A, DPF1, PRKAA1, PRKAA2, PRKAG1, PRKAG3, FGFR1, SOS2, MLST8, ACSL3, NDUFS3, NDUFS4, NDUFS6, NDUFS8, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, ATP5PD, ATP5MF, ATP5MG, CPT2
## 14 NDUFS3, NDUFS4, NDUFS6, NDUFS8, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, ATP5PD, ATP5MF, ATP5MG, ATP6V1A, ATP6V1D, ATP6V0B, PPA1
## 18 MAPK9, CPT2, PIK3CB, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, NDUFS3, NDUFS4, NDUFS6, NDUFS8, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, ATP5PD
## 21 GSTT1, MGST3, NDUFV1, NDUFA2, NDUFA5, NDUFA9, NDUFA12, NDUFB4, NDUFB5, NDUFB9, NDUFS3, NDUFS4, NDUFS6, NDUFS8, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, ATP5PD, SOD2, AKR1A1, NOX4, SOS2, MAPK9, PIK3CB, PRKD2, NFE2L2
## 3 SMAD4, PRKAA1, PRKAA2, PRKAG1, PRKAG3, SKP2, SETD7, MAPK9, PIK3CB, FOXO1, FOXO6, IL10, SOS2, CDK2, CCNB1, CCND1, CCNG2, CDKN1A, PLK1, PLK4, SOD2, G6PC3, S1PR1, S1PR4
## 4 PSMD3, PSMD9, PSMD11, PSMD6, PSMD7, PSMC1, PSMC5, PSMC6, PSMC3, PSMC4, PSME3, PSMA5, PSMA1, PSMA3, PSMB6, PSMB3, PSMB5, PSMB1, PSMB4
## 15 PSMA5, PSMA1, PSMA3, PSMB6, PSMB3, PSMB5, PSMB1, PSMB4, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD3, PSMD9, PSMD11, PSMD6, PSMD7, TRAF2, MAPK9, ATXN1L, TBPL1, NRBF2, WIPI2, WIPI1, PIK3CB
## 5 CCND1, E2F1, E2F4, TFDP2, SMAD4, ZBTB17, CDKN2C, CDKN1A, CCNE1, CDK2, SKP1, SKP2, CCNA2, CDC45, CDC7, CDK1, CCNB1, PLK1, PKMYT1, ANAPC2, ANAPC4, ANAPC7, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, PTTG1, ESPL1, BUB3, MAD2L1, MAD2L2, CHEK1, SFN, ORC1, ORC2, ORC3, ORC5, ORC6, MCM2, MCM4, MCM5, MCM7
## 7 PKMYT1, CDK1, CDK2, PLK1, SKP1, ANAPC2, ANAPC4, ANAPC7, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, FBXO43, PTTG1, ESPL1, CCNB1, MAD2L1, MAD2L2, CCNE1, PPP2CA, PPP2CB, PPP3CB
## 11 PIK3CB, MAPK9, CDK2, CDK1, CCNA2, PKMYT1, CCNB1, PLK1, MAD2L1, MAD2L2, ANAPC2, ANAPC4, ANAPC7, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15
## 24 UBE2D2, SMURF1, TRAF6, MAP3K1, BIRC2, SKP1, SKP2, ELOC, CUL4B, CUL5, SOCS3, ANAPC11, ANAPC2, ANAPC4, ANAPC7, ANAPC10, CDC26, ANAPC13, ANAPC15
## 6 CHEK1, CDKN1A, CCND1, CCNE1, CDK2, SFN, CCNB1, CDK1, GTSE1, TNFRSF10A, BCL2L1, EI24, SERPINE1, CD82, RRM2, STEAP3, CCNG2
## 10 MTMR1, MTMR8, MTMR14, INPP5F, INPP5E, PIK3CB, PIK3CG, FIG4, IMPA2, ISYNA1, INPP1, INPP5K, ALDH6A1
## 13 INPP5F, INPP5E, PIK3CB, MTMR1, MTMR8, MTMR14, PIP4P2, INPP1, IMPA2
## 16 NUDT5, PGM2, NT5DC4, IMPDH2, ENTPD4, RRM2, HDDC2, HDDC3, PDE1B, PDE6A, PDE10A, AK4, PDE8A
## 23 ENTPD4, UCK1, NT5DC4, RRM2, HDDC2, TK1, UPB1
## 17 IL10, STAT2, SOCS3, BCL2L1, PIM1, CCND1, CDKN1A, STAM2, SOS2, PIK3CB
## 19 FGF2, FGF23, CSF1, EFNA3, EFNA5, FGFR1, FLT4, SOS2, RRAS2, RASA1, RASA2, RAC3, PAK4, PIK3CB, BCL2L1, RGL1, RGL2, MAPK9, PLA2G1B, RAB5A
## 39 PPP3CB, RASA1, RASA2, FGF2, FGF23, CSF1, EFNA3, EFNA5, FGFR1, FLT4, SOS2, RRAS2, MKNK1, RAC3, TRAF2, IRAK1, TRAF6, STK3, MAP3K1, MAP3K7, MAPK9, DDIT3, DUSP1, DUSP4, DUSP2, DUSP5, DUSP6
## 58 F2R, ADORA2A, FGF2, FGF23, CSF1, EFNA3, EFNA5, FGFR1, FLT4, RAPGEF6, PRKD2, RAC3, TLN2, ITGA2B, PIK3CB
## 20 PIK3CB, CREB5, FOXO1, SOD2, ADIPOR1, CAMKK2, PRKAA1, PRKAA2, PRKAG1, PRKAG3
## 25 PPP1R3B, PIK3CB, SOCS3, MAPK9, PRKAA1, PRKAA2, PRKAG1, PRKAG3, FOXO1, G6PC3, SLC2A2, CREB5
## 27 MAP3K7, CAMKK2, ADIPOR1, PRKAA1, PRKAA2, PRKAG1, PRKAG3, PFKFB3, FBP2, G6PC3, CREB5, CCND1, CCNA2, FOXO1, SCD5, PPP2CA, PPP2CB, PPP2R3C, RAB2A, RAB8A, PIK3CB
## 29 CREB5, PPP4C, PPP3CB, FOXO1, G6PC3, PRKAA1, PRKAA2, PRKAG1, PRKAG3, SLC2A2, FBP2
## 46 PIK3CB, PPP1R3B, FLOT2, FLOT1, PRKAA1, PRKAA2, PRKAG1, PRKAG3, FOXO1, G6PC3, FBP2, SOS2, MKNK1, SOCS3, MAPK9
## 47 PIK3CB, FOXO1, SOD2, PRKAA1, PRKAA2, PRKAG1, PRKAG3
## 61 C5AR1, IRAK1, TRAF6, MAP3K7, SCD5, ADIPOR1, CAMKK2, PRKAA1, PRKAA2, PRKAG1, PRKAG3, FOXO1, FABP1, ALDH2, NOX4, CCND1, MAPK9
## 71 TRAF2, MAPK9, SOCS3, ACSL3, G6PC3, ADIPOR1, CAMKK2, PRKAA1, PRKAA2, PRKAG1, PRKAG3
## 22 TLN2, XPO1, PPP3CB, MAD2L1, BUB3, ANAPC2, ANAPC4, ANAPC7, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, PTTG1, ESPL1, CCND1, CDKN1A, CCNA2, CCNE1, CDK2, E2F1, CHEK1, PIK3CB, MAP3K1, MAPK9, BCL2L1, SMAD4, TBPL1, EGR1, EGR2, CREB5, CDKN2C
## 65 CREB5, PIK3CB, CCNE1, CDK2, EGR2, EGR3, CDKN1A, CDK1, TBPL1, CCND1, CCNA2, SKP2, TRAF2, PSMC1, HDAC10, RASA2, CHEK1
## 26 FABP1, HMGCS1, SCD5, ACSL3, CPT2, PLIN4, AQP7
## 147 ACAT2, ACAT1, ECHS1, ACSL3, CPT2, CYP2U1, ALDH2
## 28 RAB5A, RAB7B, DYNLL1, DYNLRB1, DCTN2, DCTN3, DCTN6, ACTR1B, ACTR10, TUBB3, TUBB4A, FYCO1, ARL8A, KLC2, RAB9B, STX10, ELMO2, CYFIP1, BRK1, ACTR3, ARPC1A, ARPC2, PIK3CB, PIK3CG, IRAK1, TRAF6, MAP3K7, CSE1L, KPNA3, MAPK9, SKP1, TRAF2, BIRC2, TNFRSF10A, CASP7
## 49 ELMO2, ACTR3, ARPC1A, ARPC2, TLN2, PIK3CB, FOXO1, FOXO6, GSK3A, BCL2L1, TRAF2, MAP3K7, TRAF6, MAPK9, UBE2D2, SKP1, MAP1LC3B, SEPTIN3, WIPI2, WIPI1, TECPR1
## 57 FN1, ELMO2, RAC3, ACTR3, ARPC1A, ARPC2, WIPF3, GIT2, SKAP2, IRAK1, TRAF6, TRAF2, MAP3K7, MAPK9, PIK3CB, IL10
## 74 CYFIP1, BRK1, ACTR3, ARPC1A, ARPC2, F2R, ARHGEF11, TUBB3, TUBB4A, WIPF3, IRAK1, TRAF6, TRAF2, MAP3K7, MAPK9, TNFRSF10A, CASP7, SEC24B
## 30 TRAF2, BIRC2, MAP3K7, MAPK9, CREB5, CASP10, CASP7, CSF1, SOCS3, JUNB, PIK3CB, DAB2IP
## 31 SKP1, PIK3CB, PPP3CB, RAC3, PAK4, BCL2L1, IRAK1, TRAF6, MAP3K7, MAPK9, TRAF2, TAP1, AP1S2, ELOC, CUL5, CUL4B, CHEK1, CCNB1, CDK1
## 37 PIK3CB, SOS2, RAC3, TRAF2, PPP3CB, ARHGEF11, CCND1, CREB5, TAP1, CDKN1A, E2F1
## 45 CSF1, PIK3CB, TNFRSF11A, TRAF2, TRAF6, MAP3K7, MAPK9, JUNB, PPP3CB, STAT2, SOCS3
## 52 PIK3CB, BCL2L1, MAPK9, SOD2, CYP2A6, HSPD1, IRAK1, TRAF6, MAP3K7, HSPA5, DDIT3, EIF2S1, TRAF2, NFE2L2, PPP3CB, TNFRSF10A, CASP7
## 73 TLR3, STAT2, TRAF2, CDKN1A, E2F1, MAP1LC3B, PIK3CG, PIK3CB, MAPK9, PPP3CB, FGF2, CCND1
## 85 TNFRSF10A, CASP10, CASP7, HTRA2, SPTAN1, LMNB2, PARP2, PARP3, TRAF2, EIF2S1, DDIT3, BIRC2, BCL2L1, DAB2IP, MAPK9, PIK3CB
## 32 IRAK1, TRAF6, TRAF2, BIRC2, TNFRSF11A, MAP3K7, BCL2L1, CSNK2B
## 33 SLC18A1, PPP3CB, CREB5, MAPK9, KCNJ5, PPP2CA, PPP2CB, PPP2R3C, GSK3A, LRTOMT
## 55 CREB5, PIK3CB, MAPK9, SOS2
## 56 PAX8, CREB5, HSPA5, LRP2
## 60 SLC8A3, PPP2CA, PPP2CB, PPP2R3C, MYH6, AGTR2, PPP1R1A, CREB5, PIK3CG
## 64 CREB5, SOS2, PIK3CB, JUNB, SOCS3, MAP3K1, MAPK9
## 68 SLC2A2, KCNN1, CREB5
## 76 KCNJ4, CHRM4, PIK3CG, CHRNA7, CREB5, PIK3CB
## 82 PRKD2, CREB5, KCNJ5
## 95 FGF23, FGFR1, EGR1, CREB5, CDKN1A, ARHGEF11, MMP25
## 101 CREB5, SOS2, PIK3CB, KCNJ5
## 111 PDE8A, CREB5
## 121 KCNJ5, KCNN1, PIK3CB, GNRH2
## 133 ADRA2A, ADRA2B, PPP3CB, MYH6, SLC8A3, CNGB1, PIK3CG, CREB5
## 34 TLR3, TRAF6, EIF2AK1, EIF2S1, SOCS3, STAT2, RSAD2, PPP2CA, PPP2CB, SOS2, PIK3CB, CDKN1A, CDK2, E2F1, TRAF2, PSME3, CCND1
## 40 CDKN1A, MAPK9, EGR2, EGR3, MAP3K1, PIK3CB, CASP10, CCNA2, CDK2, CCNE1, E2F1, STAT2, SOS2, SMAD4, CREB5, IRAK1, TRAF6, MAP3K7, TLR3
## 42 IRAK1, TRAF6, CSNK2B, MAP3K7, MAPK9, STAT2, EIF2AK1, RAB9B, EIF2S1, BCL2L1, CCND1, CCNE1, CDK2, PIK3CB
## 43 IRAK1, TRAF6, MAP3K7, STAT2, ISG15, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD3, PSMD11, PSMD6, PSMD7, TAP1, HES1, CDKN1A, PIK3CB, MAPK9, TRAF2, SKP2, CCND1, CCNA2, CCNE1, CDK2, E2F1
## 53 CDKN1A, ZBTB17, CCND1, CKS1B, CKS2, SKP2, CDK2, CCNE1, E2F1, LAMA4, LAMB3, FN1, ITGA2B, PIK3CB, BIRC2, BCL2L1, TRAF2, TRAF6
## 135 DNAJC3, EIF2S1, TLR3, SOCS3, STAT2, PIK3CB, TNFRSF10A, RSAD2, XPO1
## 35 IRAK1, TRAF6, MAPK9, PPP2CA, PPP2CB, IL10, PIK3CB, SERPINE1
## 50 IRAK1, TRAF6, MAP3K7, MAPK9, BCL2L1, BIRC2, LAMA4, LAMB3, PIK3CG, IL10
## 70 TLR3, PIK3CB, IRAK1, TRAF6, MAP3K7, MAPK9
## 83 CASP10, IL10, HSPA9, HSPD1, IRAK1, TRAF6, MAPK9, PLA2R1, SPHK2, RAB5A, ATP6V0B, LAMP1, PPP3CB
## 86 PIK3CB, IRAK1, TRAF6, MAP3K7, MAPK9, TLR3, ISG15, STAT2, C5AR1, C1S
## 99 IRAK1, TRAF6, MAP3K7, IL10, MARCKSL1
## 112 CASP7, C1S, IRAK1, TRAF6, MAPK9, IL10
## 130 RRAS2, PPP3CB, IL10, EGR2, EGR3, MAPK9, STAT2, PIK3CB
## 36 MED4, MED16, MED24, MED1, CCND1, MYH6, PIK3CB, FOXO1
## 160 MAP3K7, PIK3CB, C5AR1, ITGA2B, GP1BA, H2AX, MACROH2A2, H2AZ1, HDAC10
## 38 SOS2, PIK3CB, MAP3K1, MAPK9, TRAF6, IRAK1
## 63 GNRH2, MAP3K1, MAPK9, SOS2, EGR1
## 98 HTR2B, HRH1, MAPK9, PIK3CB
## 41 CASP10, TRAF2, MAP3K7, TRAF6, MAP3K1, MAPK9, ISG15, SIKE1, PIN1
## 48 MAP3K7, MAPK9, MAP1LC3B, BIRC2, TRAF2, TRAF6, BCL2L1, GPRC6A, STAT2
## 54 TRAF6, MAP3K7, MAPK9, MAPK4, MAPK6, MAPK15, TRAF2, LCN2
## 44 NT5DC4, SIRT2, SIRT4, SIRT7
## 51 DEGS1, SMPD1, ASAH2, TRAF2, MAPK9, PPP2CA, PPP2CB, PPP2R3C, PIK3CB, SPHK2, S1PR1, RAC3, S1PR3, S1PR4
## 59 SLC8A3, RRAS2, PIK3CG, EGR1, CCND1, MAP1LC3B, PRKAA1, PRKAA2, PRKAG1, PRKAG3, SPHK2, SMAD4, CCN2, SERPINE1
## 127 CCND1, KCNJ4, PPP3CB, CAMKK2, PRKAA1, PRKAA2, PRKAG1, PRKAG3, PIK3CG, KCNJ5, CDKN1A
## 62 GSTP1, CDK2, CCNE1, E2F1, FGFR1, PIK3CB, FOXO1, CDKN1A, CREB5, CCND1, SOS2
## 75 PIK3CB, RAC3, MAPK9, SOS2
## 79 PIK3CB, RAC3, BCL2L1, MAPK9, CCND1, E2F1, CDKN1A, SMAD4, BRCA2, RAD51
## 81 PIK3CB, SOS2, MAPK9, CCND1, SOCS3, TNFRSF11A, SLC2A2
## 89 CCND1, E2F1, PIK3CB, SOS2, CDKN1A
## 100 PAK4, MAPK9, SOS2, PIK3CB, CDKN1A
## 102 SPHK2, PPP3CB, PIK3CB, RAC3
## 106 PIK3CB, SOS2, PIM1, CCNA2, DUSP6, CCND1
## 108 FGF2, FGF23, FGFR1, CCND1, PIK3CB, CDKN1A, E2F1
## 113 PIK3CB, BCL2L1, SOS2, CDKN1A, CCND1, E2F1, SMAD4
## 115 SOS2, PIK3CB, CDKN1A, CCND1, E2F1
## 119 CCND1, PIK3CB, RAC3, MAPK9, SMAD4, CDKN1A, SOS2
## 128 SOS2, MAPK9, PIK3CB, RAC3, LYPLA1
## 131 PIK3CB, SOS2, CCND1, CDKN1A
## 134 RAC3, PPP3CB, SOS2, PIK3CB, CD22
## 140 ELOC, PIK3CB, SOS2, PAK4, CDKN1A
## 146 PIK3CB, MARCKSL1, SPHK2, ACTR3, ARPC1A, ARPC2
## 166 RAC3, PIK3CB, SOS2, PPP3CB, TNFRSF10A
## 66 CCR9, STAT2, SOS2, PIK3CB, PIK3CG, GSK3A, RAC3
## 67 SMAD4, FN1, NOX4, SERPINE1, MAPK9, PIK3CB, FOXO1, PIM1, CCND1, EGR1
## 69 F2R, FGF2, FGF23, FGFR1, FN1, ITGA2B, CHRM4, SOS2, RRAS2, PIK3CB, RAC3, PAK4, GIT1, CYFIP1, BRK1, ACTR3, ARPC1A, ARPC2, IQGAP3
## 155 COL9A3, LAMA4, LAMB3, FN1, ITGA2B, FLT4, TLN2, PIK3CB, RAC3, PAK4, MAPK9, CAV1, SOS2, CCND1, BIRC2
## 72 RRAS2, CCND1, PIK3CB, CAV1, CDKN1A, TIMP3, SDC1, FN1, FZD2, FZD8, SDC4, FGF2, FGFR1, SOS2, WNT5A, WNT11
## 91 MC1R, WNT5A, WNT11, FZD2, FZD8
## 107 KLF4, PIK3CB, SMAD1, SMAD5, SMAD4, WNT5A, WNT11, FZD2, FZD8, FGF2, FGFR1
## 109 CCND1, FGF2, FGF23, FGFR1, SOS2, PIK3CB, DLL3, HES1, FLT4, CDKN1A, WNT5A, WNT11, FZD2, FZD8, E2F1, BRCA2
## 110 CDX2, CDKN1A, WNT5A, WNT11, FZD2, FZD8, CCND1, SOS2, PIK3CB, CDK2, CCNE1, E2F1, SMAD4, FGF2, FGF23
## 120 CREB5, MEN1, ASH2L, RBBP5, WDR5, CDKN2C, CCND1, E2F1, CDK2, CCNE1, CDKN1A, PDE8A, WNT5A, WNT11, FZD2, FZD8
## 150 ATP6V1A, ATP6V1D, LAMTOR2, LAMTOR5, FNIP2, CASTOR2, SEH1L, SEC13, NPRL2, SKP2, MLST8, TTI1, PRKAA1, PRKAA2, WNT5A, WNT11, FZD2, FZD8, SOS2, PIK3CB
## 154 SOS2, PIK3CB, BCL2L1, E2F1, CDKN1A, CCND1, SMAD4, WNT5A, WNT11, FZD2, FZD8, NFE2L2, GSTT1, MGST3, GSTP1, TXNRD3, ACTL6A, SMARCD1, DPF1, SMARCC2, ARID2
## 77 PIK3CB, RRAS2, MLST8, PPP2CA, PPP2CB, WIPI2, WIPI1, RAB8A, PRKAA1, PRKAA2, MAPK9, BCL2L1, NRBF2, TRAF6, CAMKK2, MAP3K7, EIF2S1, MTMR14, RAB33B, MAP1LC3B, ATG4B, LAMP1, RAB7B, SNAP29
## 78 CHRNA7, E2F1, CCND1, PIK3CB, FGF2, CREB5, SOS2, KLF4, DLL3, PTGES3, KPNA3, GSTT1, MGST3
## 80 SLC2A2, PDK1, FGFR1, PIK3CB
## 142 MKNK1, PIK3CB, ELOC, SERPINE1, PDK1, PFKFB3, CDKN1A
## 163 SLC2A2, G6PC3, PIK3CB
## 84 MAPK9, NBR1, MAP1LC3B, BCL2L1, CSNK2B, FUNDC1, E2F1, RRAS2, RAB7B
## 87 CCND1, E2F1, E2F4, PIK3CB, FOXO1, CDKN1A, CDK2, CCNE1, RRAS2, CCNA2, LIN37, RBBP4, CDK1, CCNB1, RAD50, RAD9A, RAD9B, RAD1, HUS1, CHEK1, SERPINE1, PPP3CB
## 88 PIK3CB, TRAF6, CSNK2B, PPP3CB
## 96 DLL3, PPP3CB, MAPK9
## 103 PAK4, PPP3CB, SOS2, MAP3K7, MAPK9, PIK3CB, IL10
## 132 SMAD4, PPP3CB, MAPK9
## 90 F2R, TLN2, ITGA2B, PIK3CG, PIK3CB, GP5, GP1BA, GP9, SNAP23
## 92 SLC18A1, CREB5, CDK5
## 116 SLC18A1, CREB5, PPP3CB
## 145 SLC18A1, HDAC10, H2AX, MACROH2A2, H2AZ1, ADORA2A, CREB5, SOS2, CAMKK2
## 93 PDE1B, PPP3CB
## 97 KCNJ5, PER1
## 122 PPP3CB
## 124 PPP1R1A, PPP3CB
## 129
## 139 SOS2, TUBB3, TUBB4A, CDK1, HTR2B
## 141 PPP2CA, PPP2CB
## 149 SLC18A1, HTR2B, DUSP1, KCNJ5
## 151 HRH2
## 157 PLA2G1B, ARHGEF11, ADORA2A, RAMP3
## 94 SLC8A3, ADORA2A, HRH2, ORAI2, CHRNA7, F2R, HRH1, HTR2B, FGF2, FGF23, FGFR1, FLT4, TPCN1, SPHK2, PPP3CB, PDE1B
## 104 CAV1, SDC1, SDC4, NFE2L2, GSTT1, MGST3, GSTP1, PRKAA1, PRKAA2, PIK3CB, ITGA2B, DUSP1, MAP3K7, MAPK9, RAC3, SUMO3
## 105 CDKN1A, CCND1, E2F1
## 159 NCOA4, PAX8, CDKN1A, CCND1
## 114 TRAF2, BIRC2, MAPK9, SMPD1, VPS4A, TNFRSF10A, STAT2, TLR3, H2AX, MACROH2A2, H2AZ1
## 117 CASP7, BCL2L1, HTRA2, BIRC2, MAPK9
## 118 SOS2, RRAS2, PIK3CB, AGPAT2, AGPAT3, SPHK2, F2R, PIK3CG
## 123 AMOTL1, AMOTL2, LLGL1, PPP2CA, PPP2CB, MAP3K1, MAPK9, CCND1, ACTR3, ARPC1A, ARPC2, PRKAA1, PRKAA2, PRKAG1, PRKAG3, RAB8A, RAB8B, RAPGEF6
## 125 GREM1, BMP7, AMHR2, SMAD1, SMAD5, SMAD4, SMURF1, E2F4, TGIF2, PITX2, SKP1, PPP2CA, PPP2CB
## 126 AP2A1, AP2S1, SH3GLB2, EPS15, TRAF6, RNF41, SMURF1, ACTR3, ARPC1A, ARPC2, WIPF3, STAM2, VPS4A, CAV1, RAB5A, RUFY1, RAB8A, GIT1, GIT2
## 136 MYH6, UQCRC1, UQCR10, COX6A1, COX6C, COX8A, SLC8A3
## 137 PPP3CB, RAC3, PAK4, LRIG2, EFNA3, EFNA5, RASA1, SEMA3G, DPYSL5, CDK5, SEMA4F, WNT5A, PIK3CB, BMP7
## 138 IL10
## 143 BHLHE40, BHLHE41, PER1, CRY2, NPAS2, PRKAA1, PRKAA2, PRKAG1, PRKAG3, SKP1
## 156 ITGA2B, MYH6, PRKAA1, PRKAA2, PRKAG1, PRKAG3, SLC8A3
## 144 MAPK9, GIT1, ATP6V1A, ATP6V1D, ATP6V0B
## 152 ATP6V1A, ATP6V1D, ATP6V0B
## 148 WNT5A, WNT11, FZD2, FZD8, CSNK2B, RUVBL1, SMAD4, MAP3K7, CCND1, SKP1, PRICKLE1, RAC3, MAPK9, PPP3CB
## 162 LIMD1, STK3, PPP2CA, PPP2CB, LATS2, LLGL1, CCN2, SMAD4, SERPINE1, BMP7, SMAD1, WNT5A, WNT11, FZD2, FZD8, CCND1, BIRC2
## 153 ADORA2A, CNGB1, RRAS2, MAPK9, RAC3, PIK3CB, CREB5, F2R, FXYD1, PDE10A
## 158 PIK3CB, THY1
## 161 AQP7, PIK3CB
## 164
## 165 TAS1R1, PDE1B
## 167 CSF1, CD22, ITGA2B, GP9, GP1BA, GP5
## 168 CCNA2, DUSP6, SMAD1, CDKN2C, BIRC2, BCL2L1, NSD2, PAX8, CDKN1A, ZBTB17, MEN1, DDIT3, FOXO1
## Down_regulated
## 1 UBA52, RPS27A, ADRM1, CALML4, ITPR3, ATF4, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, NDUFS2, COX4I2, COX5B, COX7A2L, ATP5F1A, ATP5MC3, ATP5PF, PINK1, APAF1, MFN2, KLC4
## 2 ATF4, ITPR3, APAF1, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, NDUFS2, COX4I2, COX5B, COX7A2L, ATP5F1A, ATP5MC3, ATP5PF, ADRM1, NOTCH1, CAV2, PIK3CD, RAC2, MAPK13, CREB3, ATF6B, KLC4
## 8 TNFRSF1A, NFKB1, PIK3CD, AKT2, ADIPOR2, MAPK13, ATF4, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, NDUFS2, COX4I2, COX5B, COX7A2L
## 9 GNAQ, PLCB2, ITPR3, GNB3, GNG3, MAPK13, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, NDUFS2
## 12 ADRB3, CREB3, KDM1A, SMARCA2, SMARCE1, MAPK13, PRKG2, RPS6KA1, RPS6KB1, NDUFS2, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, COX4I2, COX5B, COX7A2L, ATP5F1A, ATP5MC3, ATP5PF, CPT1C
## 14 NDUFS2, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, COX4I2, COX5B, COX7A2L, ATP5F1A, ATP5MC3, ATP5PF
## 18 RAC2, NFKB1, MAPK13, COL1A2, PIK3CD, AKT2, GYS2, GYS1, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, NDUFS2, COX4I2, COX5B, COX7A2L, ATP5F1A, ATP5MC3, ATP5PF, G6PD, PLCB2
## 21 GSTA4, GSTT1, NDUFA3, NDUFA6, NDUFA8, NDUFA11, NDUFA13, NDUFB2, NDUFB3, NDUFB6, NDUFS2, COX4I2, COX5B, COX7A2L, ATP5F1A, ATP5MC3, ATP5PF, CYP1A1, EPHX2, NOX1, MAP2K1, MAPK13, PIK3CD, AKT2, NFKB1, ABL2
## 3 PIK3CD, AKT2, SGK3, MAP2K1, MAPK13, TNFSF10, BCL6, BNIP3, GABARAPL1, PCK2, FBXO25, FBXO32
## 4 ADRM1, PSME1
## 15 GNAQ, PLCB2, ITPR3, ADRM1, KAT5, RB1CC1, BECN1, ATG2A, PIK3CD, AKT2
## 5 CCND3, CDK4, HDAC2, CDC27, ANAPC16, SMC3, STAG1, BUB1, FZR1, CDC14B, CDC25A
## 7 MAP2K1, RPS6KA1, MAPK13, CDC27, ANAPC16, SMC3, BUB1, ITPR3, CALML4
## 11 PIK3CD, MAPK13, MAP2K1, RPS6KA1, CDC25A, AKT2, BUB1, FZR1, CDC27, ANAPC16
## 24 UBA52, RPS27A, RCHY1, PIAS2, FZR1, CDC27, ANAPC16
## 6 CCND3, CDK4, PIDD1, APAF1, SESN1, SESN2, RCHY1
## 10 MTMR2, MTMR4, PI4KA, PIK3CD, INPP5D, PIK3C2B, PLCB2, PLCG2, MINPP1, TPI1
## 13 PI4KA, PIK3CD, INPP5D, MTMR2, MTMR4, PIP4P1, PIK3C2B, PLCB2, PLCG2, IP6K1, BPNT2, ITPR3, CALML4
## 16 PRPS2, NME6, NME3, ENTPD3, ENTPD8, ENTPD6, NUDT16, PDE1A, PDE5A, PDE6G, AK8
## 23 CAD, NME6, NME3, ENTPD3, ENTPD8, ENTPD6, CTPS1, CTPS2
## 17 IL21R, CLCF1, IL6ST, IL11RA, IL31RA, IL20RA, IL20RB, IL12B, JAK3, TYK2, STAT4, STAT5B, IRF9, CCND3, PIAS2, PIK3CD, AKT2
## 19 FGF3, NTF3, NTF4, EFNA4, FGFR3, FLT3, SHC1, PLCG2, RASGRP2, ZAP70, GNB3, GNG3, CALML4, RASAL3, RAC2, PAK3, PIK3CD, AKT2, NFKB1, TBK1, RALBP1, SHOC2, MAP2K1, PLA2G6, ETS2, ABL2
## 39 CACNA1I, RASGRP2, FGF3, NTF3, NTF4, EFNA4, FGFR3, FLT3, MAP2K1, RPS6KA1, ATF4, ELK4, TNFRSF1A, RAC2, TAB2, MAP3K3, MAP3K6, MAP2K6, MAPK13, HSPB1, AKT2, NFKB1
## 58 CALML4, F2RL3, P2RY1, LPAR1, LPAR3, GNAQ, PLCB2, RASGRP2, FGF3, EFNA4, FGFR3, MAGI1, LCP2, RAC2, PFN2, ARAP3, CTNND1, MAP2K1, MAP2K6, MAPK13, PIK3CD, AKT2
## 20 PIK3CD, AKT2, CREB3, ATF4, ATF6B, RB1CC1, RPS6KB1, EIF4EBP1, ADIPOR2, NFKB1, SESN1, SESN2
## 25 RPS6KA1, PPP1R3E, PIK3CD, AKT2, RPS6KB1, GYS2, GYS1, TNFRSF1A, NFKB1, PCK2, CREB3
## 27 CAB39, ADIPOR2, PCK2, CREB3, EEF2K, GYS2, GYS1, CPT1C, PPP2R2A, PIK3CD, AKT2, RPS6KB1, EIF4EBP1
## 29 AKT2, ATF4, CREB3, PPP4R3A, GNAQ, PLCB2, ITPR3, PCK2, CPT1C, GYS2, GYS1, PHKA2, PHKG2, CALML4
## 46 PIK3CD, AKT2, GYS2, GYS1, PPP1R3E, PHKG2, PHKA2, CALML4, EXOC7, TRIP10, HK1, HK2, PCK2, RPS6KB1, EIF4EBP1, SHC1, MAP2K1
## 47 PIK3CD, AKT2, RPS6KB1, HDAC2
## 61 TAB2, NFKB1, IL12B, TRAF3, TBK1, IL17RC, TNFRSF1A, RIPK1, TAB3, TRA2B, ADIPOR2, ADH5, ALDH7A1, CPT1C, AKT2, MAP2K6, MAPK13
## 71 TNFRSF1A, NFKB1, AKT2, PCK2, ADIPOR2, CPT1C
## 22 KAT5, MAP2K1, CD4, JAK3, STAT5B, CDC27, ANAPC16, CDK4, CCND3, PIK3CD, AKT2, TNFRSF1A, CD3D, CD3E, MAP3K3, NFKB1, ELK4, ETS2, CREB3, ATF4, ATF6B, KAT2B, KAT2A, POLB
## 65 ATF4, CREB3, ATF6B, STAT5B, PIK3CD, NFKB1, CCND3, TRAF3, TRAF5, JAK3, HDAC2, HDAC3, HDAC6, IRF9, KAT2B, KAT2A, CDK4, POLB, IL6ST
## 26 ACAA1, CPT1C, ANGPTL4, PCK2
## 147 ACAA1, CPT1C, ADH5, ALDH7A1
## 28 DYNC2LI1, DYNLRB2, KLC4, M6PR, PFN2, EXOC7, FHOD1, NCKAP1L, ARPC3, PAK3, PIK3CD, PIK3C2B, TLR2, TAB2, TAB3, NFKB1, NOD1, RIPK2, MAP2K1, MAP2K6, MAPK13, FBXO22, TNFRSF1A, RIPK1, TNFSF10, AKT2
## 49 HCLS1, ARPC3, ROCK1, PFN2, PIK3CD, AKT2, RPS6KB1, PLCB2, PLCG2, ITPR3, HK1, HK2, BNIP3, TNFRSF1A, TRAF5, RIPK1, TAB2, TAB3, NFKB1, MALT1, BCL10, NOD1, RIPK2, TBK1, MAPK13, CBX3, BECN1, CALCOCO2, UBA52, RPS27A, TECPR1
## 57 RAC2, ARPC3, GNAQ, ARHGEF1, ARHGEF28, ROCK1, RPS6KA1, LIMK1, TAB2, NFKB1, MAP2K1, MAP2K6, MAPK13, TBK1, PIK3CD, AKT2, CD4, CD8A, ZAP70, LCP2
## 74 NCKAP1L, ARPC3, ARHGEF1, MYO1F, MYO5C, LPAR1, ROCK1, HCLS1, TNFRSF1A, RIPK1, TAB2, TAB3, NFKB1, MAPK13, TNFSF10, PAK3, CLDN19, CLDN11
## 30 TNFRSF1A, BAG4, TRAF5, RIPK1, TAB2, TAB3, MAP2K6, MAPK13, NFKB1, MAP2K1, CREB3, ATF4, ATF6B, PGAM5, NOD2, VCAM1, TRAF3, PIK3CD, AKT2
## 31 CD4, PIK3CD, AKT2, RPS6KB1, NFKB1, MAP2K1, GNAQ, PLCG2, ITPR3, CALML4, GNB3, GNG3, RAC2, PAK3, LIMK1, TLR2, TAB2, MAPK13, TBK1, TNFRSF1A, RIPK1, TRAF5, MAP2K6, CD3E, CD3D, AP1S1
## 37 PIK3CD, AKT2, EIF4EBP1, RPS6KB1, NFKB1, MAP2K1, RAC2, TBK1, TNFRSF1A, RIPK1, TRAF5, GNB3, GNG3, GNAQ, PLCB2, ITPR3, CALML4, CCL4, ARHGEF1, ROCK1, PTGER1, PTGER4, MAP2K6, MAPK13, ATF4, CREB3, ATF6B, CDK4
## 45 PIK3CD, AKT2, TNFRSF1A, TAB2, NFKB1, MAP2K1, MAP2K6, MAPK13, FOSL2, NOX1, LCP2, PLCG2, TYK2, IRF9
## 52 ARHGEF1, PIK3CD, AKT2, POU2F3, CYP1A1, NOX1, MAP2K6, MAPK13, NFKB1, VCAM1, TLR2, TAB2, TRAF3, TBK1, IL12B, ERO1A, ATF4, PLCB2, CALML4, TNFSF10, TNFRSF1A, APAF1
## 73 TRAF3, TBK1, TYK2, IRF9, MAPK13, MAP2K6, TNFRSF1A, NFKB1, CDK4, UBA52, RPS27A, BECN1, GNB3, GNG3, MAP2K1, PIK3CD, AKT2, PLCG2, ITPR3, CALML4, IL6ST
## 85 TNFSF10, TNFRSF1A, APAF1, PARP4, AIFM1, ITPR3, ATF4, RIPK1, NFKB1, PIDD1, PIK3CD, AKT2, MAP2K1
## 32 ZAP70, PLCG2, CARD14, BCL10, MALT1, TNFRSF1A, RIPK1, TRAF5, TRAF3, TAB2, TAB3, TNFSF13B, PIDD1, NFKB1, CCL4, VCAM1, CCL13
## 33 GNAQ, PLCB2, ITPR3, CALML4, ATF4, CREB3, ATF6B, MAPK13, GNB3, GNG3, PPP2R2A, AKT2
## 55 GNB3, GNG3, ATF4, CREB3, ATF6B, NFKB1, PIK3CD, MAP2K1, AKT2, COL1A2, COL4A6, RXFP3, PLCB2, MAPK13, SHC1
## 56 GNAQ, PLCB2, TTF1, ATF4, CREB3, ATF6B, ITPR3, GPX3, GPX8
## 60 ADRB1, ADRB2, CALML4, PPP2R2A, TPM1, MYH6, GNAQ, PLCB2, ATF4, CREB3, ATF6B, MAPK13, AKT2
## 64 ATF4, CREB3, ATF6B, GNAQ, PLCB2, ITPR3, PLCG2, SHC1, MAP2K1, STAT5B, PIK3CD, AKT2, MAP2K6, MAPK13
## 68 KCNMB2, ATF4, CREB3, ATF6B, PDX1, GNAQ, PLCB2, ITPR3, VAMP2
## 76 GNAQ, PLCB2, ITPR3, GNB3, GNG3, MAP2K1, ATF4, CREB3, PIK3CD, AKT2
## 82 GNAQ, PLCB2, ITPR3, ATF4, CREB3, ATF6B, CACNA1I, CALML4
## 95 GNAQ, PLCB2, ITPR3, GATA3, MAP2K1, CREB3, ATF4, ATF6B, ARHGEF1
## 101 NCOA1, ATF4, CREB3, ATF6B, SHC1, MAP2K1, PIK3CD, AKT2, GNAQ, PLCB2, ITPR3, CALML4
## 111 NR5A1, ATF4, CREB3, ATF6B, CYP11B1, GNAQ, PLCB2, ITPR3, CACNA1I
## 121 GNAQ, PLCB2, ITPR3, CACNA1I, MAP2K1, PIK3CD, AKT2
## 133 GNAQ, MYH6, PRKG2, KCNMB2, GTF2IRD1, PLCB2, ITPR3, ROCK1, CALML4, PDE5A, AKT2, ADRB1, ADRB2, ADRB3, ATF4, CREB3, ATF6B, MAP2K1
## 34 CLDN19, CLDN11, TRAF3, TBK1, RIPK1, NFKB1, TYK2, IRF9, PPP2R2A, MAP2K1, PIK3CD, AKT2, CDK4, TNFRSF1A, APAF1
## 40 PIK3CD, AKT2, NFKB1, APAF1, JAK3, TYK2, STAT4, STAT5B, CREB3, ATF4, ATF6B, MAP2K1, TLR2, TAB2, MAP2K6, MAPK13, TRAF3, TBK1
## 42 TRAF3, TBK1, NFKB1, TLR2, TAB2, IL12B, TYK2, IRF9, RCHY1, APAF1, CCND3, CDK4, CD3D, CD3E, PIK3CD, AKT2, JAK3, STAT5B
## 43 TLR2, TAB2, NFKB1, TRAF3, TBK1, TYK2, IRF9, APAF1, CD3E, CD3D, ADRM1, HDAC2, CIR1, TRAF5, PIK3CD, AKT2, RIPK1, MAP2K6, MAPK13, ENTPD3, ENTPD8, JAK3, PLCG2, CCND3, CDK4
## 53 APAF1, CDK4, COL4A6, ITGA2, PIK3CD, AKT2, NFKB1, TRAF3, TRAF5
## 135 PRSS3, NLRX1, NFKB1, CALCOCO2, TRAF3, TBK1, IL12B, TYK2, IRF9, PIK3CD, AKT2, CCND3, CDK4, TNFSF10, TNFRSF1A, APAF1, MAP2K1
## 35 TLR2, MAPK13, NFKB1, IL12B, PPP2R2A, TNFRSF1A, GNAQ, PLCB2, PIK3CD, AKT2, CD3D, CD3E
## 50 TAB2, MAP2K6, MAPK13, NFKB1, IL12B, TLR2, TNFRSF1A, AKT2, ALOX5, TYK2
## 70 TLR2, PIK3CD, AKT2, TAB2, NFKB1, MAP2K1, MAP2K6, MAPK13, IL12B, CCL4, RIPK1, TBK1, TRAF3
## 83 TNFRSF1A, APAF1, AKT2, CD74, MALT1, BCL10, NOD2, RIPK2, TLR2, NFKB1, MAPK13, IL12B, CALML4, LAMP2
## 86 MAS1, NFKB1, IL12B, TNFRSF1A, IL6ST, TYK2, RPS27A, UBA52, PIK3CD, PLCG2, MAPK13, TLR2, TAB2, TRAF3, TBK1, IRF9
## 99 TLR2, TAB2, NFKB1, IL12B, MAPK13
## 112 CALML4, NFKB1, MAPK13, IL12B, IRF8, NOD1
## 130 IL12B, PLCG2, ITPR3, CALML4, BCL10, MALT1, NFKB1, MAPK13, IRF9, IL17D, PIK3CD, AKT2
## 36 MAP2K1, HDAC2, HDAC3, KAT2B, KAT2A, NCOA1, MED13, MYH6, NOTCH1, NOTCH2, NOTCH3, BMP4, PLCB2, PLCG2, PIK3CD, AKT2
## 160 MAP2K1, RAC2, PLCB2, PLCG2, PIK3CD, AKT2, NFKB1, TLR2, MAPK13, MACROH2A1, HDAC2, HDAC3, HDAC6
## 38 NTF4, NTF3, MAP2K1, RPS6KA1, ATF4, MAP3K3, MAPK13, SHC1, PIK3CD, AKT2, NFKB1, PLCG2, CALML4, PRDM4, RIPK2
## 63 ATF4, GNAQ, PLCB2, ITPR3, CALML4, MAP3K3, MAP2K6, MAPK13, MAP2K1
## 98 GNAQ, PLA2G6, PLCB2, ITPR3, CALML4, MAP2K6, MAPK13, PLCG2, PIK3CD, PTGER4, TRPV4, F2RL1
## 41 TRAF3, AZI2, TBK1, RIPK1, NFKB1, MAPK13, IL12B, NLRX1
## 48 NOD1, RIPK2, NFKB1, NOD2, TAB2, TAB3, MAPK13, GABARAPL1, TRAF5, TRAF3, TBK1, NLRX1, PLCB2, ITPR3, DHX33, MFN2, RIPK1, TYK2, IRF9
## 54 TRAF3IP2, NFKB1, CCL11, IL17RC, TRAF3, TBK1, TAB2, TAB3, MAPK13, USP25, TRAF5, IL17C, IL17B, IL17D
## 44 NADSYN1, SIRT2, SIRT5, NADK2
## 51 SPTLC1, DEGS2, SGMS2, TNFRSF1A, ACER1, MAPK13, AKT2, PPP2R2A, PIK3CD, PLCB2, SGPP2, ABCC1, SGPL1, S1PR2, MAP2K1, RAC2, GNAQ, ROCK1, NFKB1
## 59 GNB3, GNG3, GNAQ, PLCB2, ITPR3, CALML4, MAP2K1, RPS6KB1, AKT2, NOTCH3, BECN1
## 127 GNAQ, MAP2K1, PLCB2, EEF2K, ITPR3, CALML4, ROCK1
## 62 PIK3CD, AKT2, ATF4, CREB3, NFKB1, MAP2K1, SRD5A2
## 75 INPP5D, PLCG2, PIK3CD, AKT2, RAC2, MAP2K6, MAPK13, LCP2, MAP2K1, ALOX5
## 79 PIK3CD, RAC2, NFKB1, AKT2, MAP2K1, RALBP1, RPS6KB1, CDK4
## 81 SHC1, PIK3CD, AKT2, MAP2K1, MAPK13, STAT5B, NFKB1, CSN2
## 89 CDK4, PIK3CD, AKT2, MAP2K1, PLCG2, JAK3, STAT5B
## 100 PLCG2, STAT5B, ABL2, PAK3, SHC1, MAP2K1, PIK3CD, AKT2, RPS6KB1, EIF4EBP1
## 102 SH2D2A, PLCG2, MAP2K1, MAPK13, HSPB1, PIK3CD, RAC2, AKT2
## 106 FLT3, PIK3CD, AKT2, NFKB1, EIF4EBP1, RPS6KB1, MAP2K1, STAT5B
## 108 FGF3, MAP2K1, CDK4, PIK3CD, AKT2
## 113 PIK3CD, AKT2, NFKB1, MAP2K1, SHC1, STAT5B, CDK4, HDAC2
## 115 PLCG2, CALML4, SHC1, MAP2K1, PIK3CD, AKT2, CDK4
## 119 PIK3CD, AKT2, MAP2K1, RAC2, RPS6KB1
## 128 MAP2K1, PIK3CD, AKT2, RPS6KB1, EIF4EBP1, RAC2, CHPT1, PLPP3, GPCPD1
## 131 PIK3CD, AKT2, MAP2K1
## 134 RAC2, PLCG2, MAP2K1, BCL10, MALT1, NFKB1, PIK3CD, AKT2, INPP5D, PIK3AP1
## 140 PIK3CD, AKT2, MAP2K1, PAK3
## 146 PIK3CD, AKT2, RPS6KB1, PLCG2, MAP2K1, PLA2G6, PLPP3, ARPC3, RAC2, LIMK1, ASAP3, INPP5D
## 166 RAC2, MAP2K1, ZAP70, LCP2, PLCG2, PIK3CD, SHC1, SH2D1B, TNFSF10
## 66 CXCL14, CCL4, CCL8, CCL11, CCL13, CCL15, CCL23, CCL28, CXCR6, CCR6, CCR7, JAK3, STAT5B, SHC1, MAP2K1, PIK3CD, AKT2, NFKB1, RAC2, ROCK1, GNB3, GNG3, GNAQ, PLCB2, PLCG2, RASGRP2, GRK3
## 67 COL1A2, COL4A6, NOX1, PLCB2, PLCG2, VCAM1, MAPK13, NFKB1, PIK3CD, AKT2, STAT5B, CDK4
## 69 LPAR1, FGF3, FGFR3, ITGA2, ITGB4, ITGB7, PIK3CD, MAP2K1, AKT2, ARHGEF1, RAC2, PAK3, ROCK1, LIMK1, NCKAP1L, ABI2, ARPC3, PFN2, SSH1, SSH3, SPATA13
## 155 COL1A2, COL4A6, COL6A2, ITGA2, ITGB4, ITGB7, ROCK1, AKT2, PIK3CD, RAC2, PAK3, CAV2, SHC1, MAP2K1, CCND3
## 72 HCLS1, MAP2K1, ARHGEF1, ROCK1, PIK3CD, AKT2, ITPR3, RPS6KB1, CAV2, TLR2, IL12B, TFAP4, COL1A2, ITGA2, FZD5, FZD10, PLCG2, WNT9A, WNT10B, MAPK13
## 91 CREB3, WNT9A, WNT10B, FZD5, FZD10, GNAQ, MAP2K1, PLCB2, CALML4
## 107 IL6ST, JAK3, SOX2, MAP2K1, PIK3CD, AKT2, BMP4, ID4, MAPK13, WNT9A, WNT10B, FZD5, FZD10, FGFR3
## 109 NCOA1, FGF3, SHC1, MAP2K1, PIK3CD, AKT2, RPS6KB1, DLL3, NOTCH1, NOTCH2, NOTCH3, WNT9A, WNT10B, FZD5, FZD10, FRAT2, CDK4
## 110 WNT9A, WNT10B, FZD5, FZD10, FRAT2, SHC1, MAP2K1, PIK3CD, AKT2, RPS6KB1, FGF3
## 120 ATF4, CREB3, ATF6B, CDK4, MAP2K1, USP8, NR5A1, CYP11B1, GNAQ, PLCB2, ITPR3, CACNA1I, WNT9A, WNT10B, FZD5, FZD10
## 150 FNIP1, SESN2, CASTOR1, WDR24, EIF4EBP1, RPS6KB1, CAB39, WNT9A, WNT10B, FZD5, FZD10, TNFRSF1A, MAP2K1, RPS6KA1, PIK3CD, AKT2, PRR5L
## 154 PLCG2, SHC1, MAP2K1, PIK3CD, AKT2, RPS6KB1, CDK4, WNT9A, WNT10B, FZD5, FZD10, FRAT2, GSTA4, GSTT1, SMARCE1, SMARCA2
## 77 PIK3CD, AKT2, MAP2K1, BNIP3, RPS6KB1, IGBP1, RB1CC1, ATG2A, SUPT20H, TBK1, BECN1, DAPK2, MTMR4, GABARAPL1, ATG4A, LAMP2, VAMP8
## 78 CDC25A, PIK3CD, AKT2, NFKB1, MAP2K1, ADRB1, ADRB2, ADRB3, ATF4, CREB3, ATF6B, RPS6KA1, CCND3, EIF4EBP1, RPS6KB1, STAT5B, BCL6, NOTCH2, FGF3, DLL3, CYP1A1, EPHX2, GSTA4, GSTT1
## 80 FGFR3, FLT3, MAP2K1, G6PD, HK1, HK2, PIK3CD, AKT2
## 142 NFKB1, MAP2K1, PIK3CD, AKT2, EIF4EBP1, RPS6KB1, PLCG2, HK1, HK2, PGK1
## 163 HK1, HK2, PIK3CD, AKT2, PLCB2
## 84 ATF4, PINK1, UBA52, RPS27A, MFN2, RHOT2, USP8, CALCOCO2, NBR1, TBK1, GABARAPL1, BECN1, PGAM5, BNIP3, BNIP3L
## 87 CDK4, CCND3, PIK3CD, AKT2, LIN9, MAP2K1, MAP2K6, MAPK13, CDC25A, TRAF3IP2, NFKB1, EIF4EBP1, ZFP36L2, TRPV4, CALML4, ITPR3
## 88 MAP2K1, PIK3CD, AKT2, RPS6KB1, NFKB1, TLR2, BATF3, CD4, CD3E, CD3D, ZAP70, MAP3K3, MAP2K6, MAPK13
## 96 DLL3, NOTCH3, NFKB1, IL12B, TYK2, STAT4, CD4, CD3E, CD3D, ZAP70, MAPK13, JAK3, STAT5B, GATA3, NOTCH1, NOTCH2
## 103 CD3D, CD3E, CD4, CD8A, ZAP70, LCP2, PAK3, MAPK13, MAP2K1, BCL10, MALT1, NFKB1, PIK3CD, AKT2, CDK4
## 132 MAPK13, IL21R, JAK3, IL6ST, TYK2, CD4, CD3E, CD3D, ZAP70, NFKB1, GATA3, STAT5B
## 90 TBXA2R, F2RL3, ARHGEF1, ROCK1, ITPR3, P2RY1, GNAQ, PLCB2, RASGRP2, COL1A2, ITGA2, PIK3CD, LCP2, PLCG2, AKT2, PRKG2, MAPK13, PTGS1, VAMP8
## 92 ATF4, CREB3, ATF6B, NFKB1
## 116 CALML4, ATF4, CREB3, ATF6B, HDAC2
## 145 HDAC2, HDAC3, HDAC6, MACROH2A1, GNB3, GNG3, ATF4, CREB3, ATF6B, SHC1, MAP2K1, CALML4
## 93 ADRB1, ADRB2, ADRB3, PTGER4, PDE1A, EDN3, GNAQ, PLCB2, ITPR3, CALML4, PRKG2
## 97 CALML4, ITPR3, GNB3, GNG3, CACNA1I, PRKG2, GNAQ, PLCB2, PER3
## 122 GNAQ, PLCB2, ITPR3, GNB3, GNG3, GRK3
## 124 CALML4, ATF4, MAP2K1, RPS6KA1, ITPR3, GNAQ, PLCB2
## 129 ADRB1, ADRB2, ADRB3, VAMP2, GNAQ, PLCB2, ITPR3, CALML4, PRKG2
## 139 LPAR1, MAP2K1, ADRB1, GNAQ, PLCB2, ITPR3, PRKG2
## 141 PRKG2, MAP2K1, GNAQ, PLCB2, ITPR3
## 149 GNAQ, PLCB2, ITPR3, ALOX5, PTGS1, GNB3, GNG3, MAP2K1
## 151 GNAQ, PLCB2, ITPR3, CALML4, KCNJ10
## 157 EDN3, GNAQ, PLA2G6, KCNMB2, CALML4, PLCB2, ITPR3, MAP2K1, ARHGEF1, ROCK1
## 94 ADRB1, ADRB2, ADRB3, CACNA1I, CASQ1, CYSLTR1, LTB4R2, PTGER1, TBXA2R, GNAQ, FGF3, FGFR3, PLCB2, PLCG2, ITPR3, CALML4, PHKG2, PHKA2, PDE1A
## 104 CAV2, CALML4, TRPV4, GSTA4, GSTT1, PIK3CD, AKT2, TNFRSF1A, NFKB1, MAP2K6, MAPK13, VCAM1, BMP4, NOX1, RAC2, SUMO1
## 105 FGFR3, MAP2K1, DAPK2, CDK4
## 159 MAP2K1
## 114 TNFRSF1A, TRAF5, RIPK1, SPATA2, PGAM5, CHMP2A, TNFSF10, JAK3, TYK2, STAT4, STAT5B, IRF9, USP21, AIFM1, MACROH2A1
## 117 TNFRSF1A, APAF1, BECN1
## 118 SHC1, PIK3CD, AKT2, PLCG2, AGPAT4, AGPAT5, MAP2K1, PLPP3, LPAR1, LPAR3, PLCB2
## 123 CRB3, CLDN19, CLDN11, F11R, MPP4, TJP3, LLGL2, PPP2R2A, CDK4, HCLS1, ARPC3, ROCK1, IGSF5, MAGI1
## 125 NBL1, BMP4, BMP5, ZFYVE16, ID4, ROCK1, RPS6KB1
## 126 AP2A2, ZFYVE16, FGFR3, EPN1, GRK3, ARPC3, USP8, CHMP2A, CAV2, EHD3, ASAP3, ARAP3
## 136 TPM1, MYH6, COX4I2, COX5B, COX7A2L
## 137 NTN1, PLCG2, RAC2, PAK3, ROCK1, EFNA4, SEMA3B, LIMK1, DPYSL2, PLXNB1, PIK3CD, SSH1, SSH3
## 138 TLR2, NFKB1, NOD2, IL12B, STAT4, IL21R, GATA3
## 143 PER3
## 156 ITGA2, ITGB4, ITGB7, TPM1, MYH6
## 144 PLCG2, F11R, IGSF5, MAPK13, NFKB1, NOD1
## 152 ERO1A, PLCG2
## 148 WNT9A, WNT10B, WIF1, DKK2, DKK4, SERPINF1, LGR4, LGR6, RNF43, FZD5, FZD10, FRAT2, NKD2, CTNNBIP1, SOX17, CCND3, VANGL2, RAC2, PLCB2
## 162 FRMD6, RASSF6, PPP2R2A, LLGL2, BMP4, BMP5, WNT9A, WNT10B, FZD5, FZD10, NKD2, CCND3, SOX2
## 153 GPHA2, ADRB1, ADRB2, EDN3, CALML4, RAC2, ARAP3, PIK3CD, AKT2, MAP2K1, CREB3, NFKB1, ROCK1
## 158 F11R, CLDN19, CLDN11, VCAM1, PIK3CD, CTNND1, MAPK13, PLCG2, THY1, ROCK1, RAC2
## 161 ADRB1, ADRB2, ADRB3, PRKG2, PIK3CD, AKT2, PTGS1
## 164 RPS27A, UBA52
## 165 GNB3, PLCB2, ITPR3, P2RY1, PDE1A
## 167 CD34, FLT3, CD2, CD4, CD8A, CD3D, CD3E, IL11RA, ITGA2
## 168 HDAC2, CCNT1, FLT3, BCL6, ITGB7, ELK4, NFKB1
## all_pathway_genes
## 1 ADORA2A, GNAL, GNAS, DRD2, GNAI1, GNAI3, GNAI2, ADCY5, PRKACA, PRKACB, PRKACG, DRD1, UBA1, UBA7, UBA52, RPS27A, UBB, UBC, UBE2L3, UBE2L6, UBE2J2, UBE2J1, UBE2G2, UBE2G1, PRKN, SNCA, GPR37, SEPTIN5, SNCAIP, PSMA6, PSMA2, PSMA4, PSMA7, PSMA8, PSMA5, PSMA1, PSMA3, PSMB6, PSMB7, PSMB3, PSMB2, PSMB5, PSMB1, PSMB4, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD1, PSMD3, PSMD9, PSMD12, PSMD11, PSMD6, PSMD7, PSMD13, PSMD4, PSMD14, PSMD8, ADRM1, SEM1, UCHL1, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, MAPT, RYR3, ITPR1, ITPR2, ITPR3, PLCG1, HSPA5, ATF6, DDIT3, ERN1, XBP1, EIF2AK3, EIF2S1, ATF4, TH, MAOB, MAOA, SLC6A3, SLC18A1, SLC18A2, SLC11A2, SLC39A2, SLC39A3, SLC39A1, SLC39A4, SLC39A5, SLC39A6, SLC39A7, SLC39A8, SLC39A9, SLC39A10, SLC39A11, SLC39A12, SLC39A13, SLC39A14, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFC1, NDUFC2, NDUFC2-KCTD14, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, ATP5F1A, ATP5F1B, ATP5F1C, ATP5F1D, ATP5F1E, ATP6, ATP5PB, ATP5MC1, ATP5MC2, ATP5MC3, ATP5PD, ATP5PO, ATP5PF, ATP8, PINK1, MCU, LRRK2, HTRA2, TRAP1, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, CYCS, APAF1, CASP9, CASP3, PARK7, BCL2L1, BAX, MFN1, MFN2, KIF5A, KIF5B, KIF5C, KLC3, KLC1, KLC2, KLC4, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3, TUBB6, TUBB, TUBB1, TUBB2A, TUBB3, TUBB4A, TUBB8, TUBB2B, TUBB4B, TP53, DUSP1, NFE2L2, TXN, TXN2, DAXX, MAP3K5, MAPK8, MAPK10, MAPK9, SOD1, KEAP1
## 2 PRNP, NCAM1, NCAM2, LAMC1, SOD1, STIP1, PRKACA, PRKACB, PRKACG, BAX, FYN, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S, HSPA5, EIF2AK3, EIF2S1, ATF4, DDIT3, RYR1, RYR2, RYR3, ITPR1, ITPR2, ITPR3, CASP12, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, BAD, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, APAF1, CYCS, CASP9, CASP3, MCU, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFC1, NDUFC2, NDUFC2-KCTD14, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, ATP5F1A, ATP5F1B, ATP5F1C, ATP5F1D, ATP5F1E, ATP6, ATP5PB, ATP5MC1, ATP5MC2, ATP5MC3, ATP5PD, ATP5PO, ATP5PF, ATP8, PSMA6, PSMA2, PSMA4, PSMA7, PSMA8, PSMA5, PSMA1, PSMA3, PSMB6, PSMB7, PSMB3, PSMB2, PSMB5, PSMB1, PSMB4, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD1, PSMD3, PSMD9, PSMD12, PSMD11, PSMD6, PSMD7, PSMD13, PSMD4, PSMD14, PSMD8, ADRM1, SEM1, C5, C6, C7, C8A, C8B, C8G, C9, C1QA, C1QB, C1QC, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, NOTCH1, CAV1, CAV2, CAV3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PRKCD, CYBB, CYBA, NCF4, NCF1, NCF2, RAC1, RAC2, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, MAPK1, MAPK3, CREB1, ATF2, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, EGR1, CCL5, IL1A, IL1B, IL6, TNF, GSK3B, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, KIF5A, KIF5B, KIF5C, KLC3, KLC1, KLC2, KLC4, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3, TUBB6, TUBB, TUBB1, TUBB2A, TUBB3, TUBB4A, TUBB8, TUBB2B, TUBB4B
## 8 IL6, IL6R, SOCS3, TNF, TNFRSF1A, NFKB1, RELA, INS, INSR, IRS1, IRS2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, GSK3A, GSK3B, NR1H3, RXRA, SREBF1, MLX, MLXIP, MLXIPL, PKLR, LEP, LEPR, ADIPOQ, ADIPOR1, ADIPOR2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, MAPK11, MAPK12, MAPK13, MAPK14, PPARA, PPARG, CDC42, RAC1, MAP3K11, MAPK8, MAPK10, MAPK9, ITCH, ERN1, TRAF2, MAP3K5, FOS, JUN, IL1A, IL1B, IKBKB, XBP1, CEBPA, CYP2E1, FASLG, CXCL8, TGFB1, EIF2AK3, EIF2S1, ATF4, DDIT3, BCL2L11, BAX, FAS, CASP8, BID, CYCS, CASP3, CASP7, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFC1, NDUFC2, NDUFC2-KCTD14, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A
## 9 SLC17A6, SLC17A8, SLC17A7, GRIA1, GRIA2, GRIA3, GRIA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRM1, GRM5, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, NAPEPLD, PRKCA, PRKCB, PRKCG, DAGLA, DAGLB, PTGS2, ABHD6, FAAH, CNR1, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, KCNJ3, KCNJ6, KCNJ9, KCNJ5, CACNA1A, CACNA1B, MAPK1, MAPK3, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, MGLL, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFC1, NDUFC2, NDUFC2-KCTD14, SLC32A1, RIMS1, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB3, GABRB2, GABRG1, GABRG2, GABRG3, GABRD, GABRE, GABRQ, GABRP, GABRR1, GABRR2, GABRR3
## 12 ADRB3, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, ADCY10, PRKACA, PRKACB, PRKACG, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, PRDM16, ZNF516, KDM1A, UCP1, KDM3A, KDM3B, SMARCA2, SMARCA4, SMARCB1, SMARCC1, SMARCC2, SMARCD1, SMARCD2, SMARCD3, SMARCE1, ACTG1, ACTB, ACTL6A, ACTL6B, ARID1B, ARID1A, DPF1, DPF3, PPARG, MAP3K5, MAP2K3, MAPK11, MAPK12, MAPK13, MAPK14, PPARGC1A, ATF2, SIRT6, FGF21, PLIN1, LIPE, PNPLA2, MGLL, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, GCG, BMP8B, BMP8A, CNR1, NPPA, NPPB, NPR1, PRKG1, PRKG2, KLB, FGFR1, FRS2, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, TSC1, TSC2, RHEB, RPTOR, MTOR, MLST8, AKT1S1, RPS6KB1, RPS6KB2, RPS6, ACSL6, ACSL4, ACSL1, ACSL5, ACSL3, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFC1, NDUFC2, NDUFC2-KCTD14, NDUFAF1, NDUFAF2, NDUFAF3, NDUFAF4, NDUFAF5, NDUFAF6, NDUFAF7, NDUFAF8, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX1, COX2, COX3, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, COX10, COX11, COX14, COX15, COX16, COX17, COX18, COX19, COX20, COA1, COA3, COA4, COA5, COA6, COA7, ATP5F1A, ATP5F1B, ATP5F1C, ATP5F1D, ATP5F1E, ATP5PO, ATP6, ATP5PB, ATP5MC1, ATP5MC2, ATP5MC3, ATP5PD, ATP5ME, ATP5MF, ATP5PF, ATP8, ATP5MG, CPT2, SLC25A29, SLC25A20, CPT1A, CPT1B, CPT1C
## 14 ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFC1, NDUFC2, NDUFC2-KCTD14, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX10, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, COX11, COX15, COX17, CYCS, ATP5F1A, ATP5F1B, ATP5F1C, ATP5F1D, ATP5F1E, ATP5PO, ATP6, ATP5PB, ATP5MC1, ATP5MC2, ATP5MC3, ATP5PD, ATP5ME, ATP5MF, ATP5MG, ATP5PF, ATP8, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C2, ATP6V1C1, ATP6V1D, ATP6V1E2, ATP6V1E1, ATP6V1F, ATP6V1G1, ATP6V1G3, ATP6V1G2, ATP6V1H, TCIRG1, ATP6V0A2, ATP6V0A4, ATP6V0A1, ATP6V0C, ATP6V0B, ATP6V0D1, ATP6V0D2, ATP6V0E1, ATP6V0E2, ATP6AP1, ATP4A, ATP4B, ATP12A, PPA2, PPA1, LHPP
## 18 SLC2A1, SLC2A4, GFPT2, GFPT1, CAMK2A, CAMK2D, CAMK2B, CAMK2G, TNNI3, RYR2, PLN, ATP2A1, ATP2A3, ATP2A2, SP1, AGT, REN, CMA1, PRKCB, AGER, CYBB, NCF1, CYBA, NCF2, NCF4, RAC1, RAC2, AGTR1, NFKB1, RELA, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, MMP2, MMP9, COL1A1, COL1A2, COL3A1, TGFB1, TGFB2, TGFB3, CD36, PPARA, CPT1B, PDK2, PDK3, PDK4, PRKCA, PRKCD, PTPA, PPP1CA, PPP1CB, PPP1CC, CTSD, PRKCZ, CPT2, INS, INSR, IRS1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, AKT1, AKT2, AKT3, MTOR, GSK3B, GYS2, GYS1, TBC1D4, MPC1L, MPC1, MPC2, PDHA2, PDHA1, PDHB, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFC1, NDUFC2, NDUFC2-KCTD14, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, ATP5F1A, ATP5F1B, ATP5F1C, ATP5F1D, ATP5F1E, ATP6, ATP5PB, ATP5MC1, ATP5MC2, ATP5MC3, ATP5PD, ATP5PO, ATP5PF, ATP8, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, PRKCG, NOS3, GAPDH, PARP1, G6PD, GSR, TGFBR1, TGFBR2, SMAD2, SMAD3, PLCB1, PLCB2, PLCB3, PLCB4, ACE
## 21 AS3MT, GSTA5, GSTA2, GSTA4, GSTO2, GSTM4, GSTT2, GSTT1, GSTM3, MGST1, MGST3, GSTM1, GSTM5, MGST2, GSTA1, GSTM2, GSTA3, GSTO1, GSTT2B, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, NDUFV1, NDUFV2, NDUFV3, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA4L2, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFAB1, NDUFA11, NDUFA12, NDUFA13, NDUFB1, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB6, NDUFB7, NDUFB8, NDUFB9, NDUFB10, NDUFB11, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFC1, NDUFC2, NDUFC2-KCTD14, SDHA, SDHB, SDHC, SDHD, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, ATP5F1A, ATP5F1B, ATP5F1C, ATP5F1D, ATP5F1E, ATP6, ATP5PB, ATP5MC1, ATP5MC2, ATP5MC3, ATP5PD, ATP5PO, ATP5PF, ATP8, SOD2, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, SOD1, CAT, SLC26A1, SLC26A2, SLC26A6, SLC26A9, CYP1A2, CYP2E1, CYP2F1, CYP1A1, CYP1B1, EPHX1, EPHX2, EPHX3, EPHX4, AKR1A1, AKR1C1, AKR1C2, AKR1C3, AKR1C4, NQO1, CBR1, AHR, LPO, NOX4, CYBA, NOX1, NCF1, NCF2, EGF, EGFR, HGF, MET, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, MAP3K5, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, JUN, FOS, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, RAC1, PDPK1, AKT1, AKT2, AKT3, FOXO3, BAD, PTPN1, PTEN, CHUK, IKBKB, IKBKG, NFKBIA, RELA, NFKB1, PRKCD, PTPRJ, ACP1, PTPN11, SRC, ABL1, ABL2, PRKD1, PRKD3, PRKD2, PTK2, PLD1, PLD2, MAP3K14, HIF1A, ARNT, VEGFA, KEAP1, NFE2L2, HMOX1
## 3 TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD4, SMAD3, STK11, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, NLK, SKP2, MDM2, SETD7, CREBBP, EP300, SIRT1, USP7, SLC2A4, MAPK8, MAPK10, MAPK9, STK4, IGF1, IGF1R, INS, INSR, IRS1, IRS2, IRS4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, CHUK, IKBKB, PTEN, AKT1, AKT2, AKT3, SGK1, SGK2, SGK3, C8orf44-SGK3, FOXO1, FOXO3, FOXO4, FOXO6, GRM1, HOMER1, HOMER2, HOMER3, AGAP2, CSNK1E, TPTEP2-CSNK1E, IL6, IL10, STAT3, EGF, EGFR, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, BRAF, RAF1, ARAF, MAP2K1, MAP2K2, MAPK1, MAPK3, MAPK11, MAPK12, MAPK13, MAPK14, CDK2, PRMT1, FOXG1, CCNB1, CCNB2, CCNB3, CCND1, CCND2, CCNG2, CDKN2B, CDKN2D, CDKN1A, CDKN1B, RBL2, PLK1, PLK2, PLK3, PLK4, GADD45A, GADD45B, GADD45G, FASLG, BCL2L11, TNFSF10, BCL6, BNIP3, ATG12, GABARAP, GABARAPL1, GABARAPL2, CAT, SOD2, ATM, PCK1, PCK2, G6PC1, G6PC2, G6PC3, IL7R, KLF2, S1PR1, S1PR4, RAG1, RAG2, FBXO25, FBXO32
## 4 PSMD3, PSMD9, PSMD12, PSMD11, PSMD6, PSMD7, PSMD13, PSMD14, PSMD8, SEM1, PSMD4, PSMD2, PSMD1, ADRM1, PSMC2, PSMC1, PSMC5, PSMC6, PSMC3, PSMC4, PSME1, PSME2, PSME3, PSME4, PSMA6, PSMA2, PSMA4, PSMA7, PSMA8, PSMA5, PSMA1, PSMA3, PSMB6, PSMB7, PSMB3, PSMB2, PSMB5, PSMB1, PSMB4, PSMB9, PSMB10, PSMB8, PSMB11, IFNG, PSMF1, POMP
## 15 TRPC3, GRM1, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, GRIA1, GRIA2, GRIA3, CACNA1A, ITPR1, ITPR2, ITPR3, ATXN2L, ATXN2, ATXN3, ATXN3L, RYR1, PDYN, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, MCU, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, CYCS, AFG3L2, OMA1, OPA1, FGF14, SPTBN2, PSMA6, PSMA2, PSMA4, PSMA7, PSMA8, PSMA5, PSMA1, PSMA3, PSMB6, PSMB7, PSMB3, PSMB2, PSMB5, PSMB1, PSMB4, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD1, PSMD3, PSMD9, PSMD12, PSMD11, PSMD6, PSMD7, PSMD13, PSMD4, PSMD14, PSMD8, ADRM1, SEM1, ERN1, TRAF2, MAP3K5, MAPK8, MAPK10, MAPK9, ATXN1L, ATXN1, KAT5, RORA, ATP2A1, ATP2A3, ATP2A2, SLC1A6, CIC, PUM2, PUM1, TBPL2, TBPL1, TBP, RBPJL, RBPJ, SP1, GTF2B, NFYA, XBP1, MYOD1, MTOR, ULK1, ULK2, ATG101, ATG13, RB1CC1, AMBRA1, BECN1, BECN2, PIK3R4, ATG14, NRBF2, PIK3C3, ATG2A, ATG2B, WIPI2, WIPI1, KCNC3, KCND3, RELN, VLDLR, DAB1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, TWNK, ATXN8OS, ATXN10, BEAN1, NOP56
## 5 CCND1, CCND2, CCND3, CDK4, CDK6, RB1, RBL1, RBL2, ABL1, HDAC1, HDAC2, E2F1, E2F2, E2F3, E2F4, E2F5, TFDP1, TFDP2, GSK3B, TGFB1, TGFB2, TGFB3, SMAD2, SMAD3, SMAD4, MYC, ZBTB17, CDKN2A, CDKN2B, CDKN2C, CDKN2D, CDKN1B, CDKN1C, CDKN1A, CCNE1, CCNE2, CDK2, SKP1, CUL1, RBX1, SKP2, CCNA2, CCNA1, CDC6, CDC45, CDC7, DBF4, DBF4B, CDK1, CCNB1, CCNB2, CCNB3, CDC25B, CDC25C, YWHAZ, YWHAB, YWHAQ, YWHAE, YWHAH, YWHAG, PLK1, WEE1, WEE2, PKMYT1, CCNH, CDK7, ANAPC1, ANAPC2, CDC27, ANAPC4, ANAPC5, CDC16, ANAPC7, CDC23, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, ANAPC16, CDC20, PTTG1, PTTG2, ESPL1, SMC1A, SMC1B, SMC3, STAG2, STAG1, RAD21, TTK, BUB1, BUB3, BUB1B, MAD1L1, MAD2L1, MAD2L2, FZR1, CDC14B, CDC14A, ATR, ATM, TP53, CHEK1, CHEK2, CREBBP, EP300, PRKDC, MDM2, GADD45A, GADD45B, GADD45G, PCNA, SFN, CDC25A, ORC1, ORC2, ORC3, ORC4, ORC5, ORC6, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7
## 7 INS, IGF1, IGF1R, PGR, AR, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, AURKA, CPEB1, CPEB2, CPEB3, CPEB4, MOS, MAP2K1, MAPK1, MAPK3, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, PKMYT1, YWHAZ, YWHAB, YWHAQ, YWHAE, YWHAH, YWHAG, SPDYA, SPDYC, SPDYE2B, SPDYE18, SPDYE11, SPDYE16, SPDYE17, SPDYE1, SPDYE4, SPDYE3, SPDYE2, SPDYE5, SPDYE6, SPDYE15, CDK1, CDK2, MAPK11, MAPK12, MAPK13, MAPK14, PPP1CA, PPP1CB, PPP1CC, SLK, PLK1, CDC25C, CCNB2, RBX1, CUL1, SKP1, BTRC, FBXW11, FBXO5, ANAPC1, ANAPC2, CDC27, ANAPC4, ANAPC5, CDC16, ANAPC7, CDC23, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, ANAPC16, CDC20, FBXO43, PTTG1, PTTG2, ESPL1, REC8, STAG3, SMC1A, SMC1B, SMC3, CCNB1, BUB1, MAD2L1, MAD2L2, MAD1L1, CCNE1, CCNE2, SGO1, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PPP2R5A, PPP2R1B, PPP2R1A, PPP2CA, PPP2CB, PLCZ1, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, CAMK2A, CAMK2D, CAMK2B, CAMK2G
## 11 PGR, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, GNAI1, GNAI3, GNAI2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, AURKA, CPEB1, CPEB2, CPEB3, CPEB4, SPDYA, SPDYC, SPDYE2B, SPDYE18, SPDYE11, SPDYE16, SPDYE17, SPDYE1, SPDYE4, SPDYE3, SPDYE2, SPDYE5, SPDYE6, SPDYE15, CDK2, CDK1, CCNA2, CCNA1, MOS, HSP90AA1, HSP90AB1, MAP2K1, MAPK1, MAPK3, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, PKMYT1, CCNB1, CCNB2, CCNB3, STK10, PLK1, CDC25A, CDC25B, CDC25C, INS, IGF1, IGF1R, AKT1, AKT2, AKT3, PDE3B, KRAS, ARAF, BRAF, RAF1, BUB1, MAD1L1, MAD2L1, MAD2L2, FZR1, ANAPC1, ANAPC2, CDC27, ANAPC4, ANAPC5, CDC16, ANAPC7, CDC23, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, ANAPC16, KIF22
## 24 UBB, UBC, UBA52, RPS27A, UBA1, SAE1, UBA2, UBA3, UBA7, UBA6, UBE2A, UBE2B, UBE2C, UBE2D4, UBE2D1, UBE2D2, UBE2D3, UBE2E3, UBE2E1, UBE2E2, UBE2F, UBE2G1, UBE2G2, UBE2H, UBE2I, UBE2J1, UBE2J2, UBE2L3, UBE2L6, UBE2M, UBE2NL, UBE2N, UBE2O, UBE2Q1, UBE2Q2, UBE2QL1, UBE2R2, CDC34, UBE2S, UBE2U, UBE2W, UBE2Z, UBE2K, BIRC6, UBE3A, UBE3B, UBE3C, SMURF1, SMURF2, ITCH, WWP1, WWP2, TRIP12, NEDD4, NEDD4L, HUWE1, UBR5, HERC1, HERC2, HERC3, HERC4, UBE4A, UBE4B, STUB1, PPIL2, PRPF19, UBOX5, MDM2, CBL, CBLB, CBLC, PRKN, SIAH1, PML, TRAF6, MAP3K1, COP1, RCHY1, BIRC2, BIRC3, XIAP, BIRC7, PIAS1, PIAS2, PIAS3, PIAS4, SYVN1, NHLRC1, AIRE, MGRN1, BRCA1, FANCL, MID1, TRIM32, TRIM37, RBX1, CUL1, SKP1, BTRC, FBXW11, SKP2, FBXW7, FBXO2, FBXO4, CUL2, ELOC, ELOB, VHL, CUL3, KEAP1, KLHL9, KLHL13, RHOBTB2, RHOBTB1, CUL4B, CUL4A, DDB1, DDB2, ERCC8, DET1, RNF7, CUL5, SOCS1, SOCS3, CUL7, FBXW8, ANAPC11, ANAPC2, CDC20, FZR1, ANAPC1, CDC27, ANAPC4, ANAPC5, CDC16, ANAPC7, CDC23, ANAPC10, CDC26, ANAPC13, ANAPC15, ANAPC16
## 6 ATM, CHEK2, ATR, CHEK1, GORAB, CDKN2A, MDM2, MDM4, TP53, CDKN1A, CCND1, CCND2, CCND3, CDK4, CDK6, CCNE1, CCNE2, CDK2, SFN, RPRM, CCNB1, CCNB2, CDK1, GADD45A, GADD45B, GADD45G, GTSE1, FAS, PIDD1, TNFRSF10A, TNFRSF10B, CASP8, BID, BAX, PMAIP1, BBC3, TP53AIP1, SIVA1, BCL2L1, BCL2, TP53I3, EI24, SHISA5, PERP, ZMAT3, SIAH1, CYCS, APAF1, CASP9, CASP3, AIFM2, IGFBP3, IGF1, SERPINE1, ADGRB1, CD82, THBS1, SERPINB5, DDB2, RRM2B, RRM2, SESN1, SESN3, SESN2, PTEN, TSC2, STEAP3, COP1, RCHY1, CCNG1, CCNG2, PPM1D, TP73
## 10 PIK3C3, MTM1, MTMR1, MTMR2, MTMR3, MTMR4, MTMR8, MTMR6, MTMR7, MTMR14, PI4KA, PI4KB, PI4K2A, PI4K2B, SACM1L, INPP5F, PIP5K1C, PIP5K1A, PIP5K1B, PIP5KL1, OCRL, INPP5B, INPP5E, SYNJ1, SYNJ2, PIK3CA, PIK3CD, PIK3CB, PIK3CG, PTEN, INPP5D, INPPL1, PIK3C2G, PIK3C2A, PIK3C2B, INPP4A, INPP4B, PIKFYVE, FIG4, PIP4K2C, PIP4K2A, PIP4K2B, PLCB1, PLCB2, PLCB3, PLCB4, PLCD1, PLCD3, PLCD4, PLCE1, PLCG1, PLCG2, PLCZ1, PLCH1, PLCH2, IMPA2, IMPA1, CDIPT, ISYNA1, INPP1, INPP5A, INPP5K, INPP5J, MINPP1, ITPKB, ITPKA, ITPKC, ITPK1, IPMK, IPPK, MIOX, ALDH6A1, TPI1
## 13 PI4KA, PI4KB, PI4K2A, PI4K2B, SACM1L, INPP5F, PIP5K1C, PIP5K1A, PIP5K1B, OCRL, INPP5B, INPP5E, SYNJ1, SYNJ2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, INPP5D, INPPL1, INPP4A, INPP4B, PIKFYVE, MTM1, MTMR1, MTMR2, MTMR3, MTMR4, MTMR8, MTMR6, MTMR7, MTMR14, PIP4K2C, PIP4K2A, PIP4K2B, PIP4P1, PIP4P2, PIK3C3, PIK3C2G, PIK3C2A, PIK3C2B, PLCB1, PLCB2, PLCB3, PLCB4, PLCD1, PLCD3, PLCD4, PLCE1, PLCG1, PLCG2, PLCZ1, IPMK, ITPKB, ITPKA, ITPKC, INPP5A, ITPK1, IPPK, IP6K1, IP6K2, IP6K3, PPIP5K1, PPIP5K2, INPP1, IMPA2, IMPA1, BPNT2, DGKZ, DGKD, DGKI, DGKA, DGKE, DGKB, DGKH, DGKG, DGKQ, DGKK, CDS1, CDS2, CDIPT, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4
## 16 NUDT9, ADPRM, NUDT5, PGM1, PGM2, PRPS1L1, PRPS2, PRPS1, PPAT, GART, PFAS, PAICS, ADSL, ATIC, APRT, NT5C2, NT5C1A, NT5C1B, NT5C, NT5M, NT5C1B-RDH14, NT5DC4, NT5E, PNP, LACC1, HPRT1, IMPDH1, IMPDH2, NME6, NME7, NME2, NME4, NME1, NME3, NME1-NME2, AK9, ENTPD3, ENTPD8, ENTPD1, CANT1, ENTPD4, ENTPD5, ENTPD6, NUDT16, ITPA, XDH, NUDT2, GMPS, GMPR, GMPR2, GDA, GUK1, RRM1, RRM2B, RRM2, HDDC2, DGUOK, DCK, HDDC3, PRUNE1, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, ADCY10, GUCY1A2, GUCY1A1, GUCY1B1, GUCY2C, GUCY2D, GUCY2F, NPR1, NPR2, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE5A, PDE6A, PDE6B, PDE6C, PDE6D, PDE6G, PDE6H, PDE9A, PDE10A, PDE11A, ADSS1, ADSS2, AMPD2, AMPD3, AMPD1, ADK, ADA, ADA2, AK7, AK4, AK5, AK2, AK1, AK8, AK6, AK3, ENTPD2, NTPCR, ENPP1, ENPP3, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8B, PDE8A, FHIT, ENPP4, PAPSS2, PAPSS1, URAD, ALLC
## 23 CAD, DHODH, UMPS, CMPK1, CMPK2, NME6, NME7, NME2, NME4, NME1, NME3, NME1-NME2, AK9, ENTPD3, ENTPD8, ENTPD1, CANT1, ENTPD4, ENTPD5, ENTPD6, ENPP1, ENPP3, ASMTL, NUDT2, CTPS1, CTPS2, UCK1, UCK2, UCKL1, NT5C2, NT5C1A, NT5C1B, NT5C, NT5M, NT5C1B-RDH14, NT5DC4, NT5E, UPP2, UPP1, NT5C3A, NT5C3B, CDA, RRM1, RRM2B, RRM2, DCTPP1, HDDC2, DCK, DCTD, DTYMK, DUT, TYMP, TK2, TK1, TYMS, DPYD, DPYS, UPB1
## 17 IL2, IL4, IL7, IL9, IL15, IL21, TSLP, IL2RA, IL2RB, IL2RG, IL4R, IL7R, IL9R, IL15RA, IL21R, CRLF2, IL3, IL5, CSF2, IL3RA, IL5RA, CSF2RA, CSF2RB, IL6, IL11, IL13, IL27, IL31, OSM, LIF, CNTF, CTF1, CLCF1, IL6R, IL6ST, IL11RA, IL13RA1, IL13RA2, IL27RA, IL31RA, OSMR, LIFR, CNTFR, IL10, IL19, IL22, IL20, IL24, IL26, IL10RA, IL10RB, IL20RA, IL20RB, IL22RA1, IL22RA2, IL12A, IL12B, IL23A, IL12RB1, IL12RB2, IL23R, EPO, GH1, GH2, CSH1, CSH2, PRL, THPO, CSF3, LEP, EPOR, GHR, PRLR, MPL, CSF3R, LEPR, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNE, IFNK, IFNL1, IFNL2, IFNL3, IFNW1, IFNAR1, IFNAR2, IFNLR1, IFNG, IFNGR1, IFNGR2, EGF, PDGFA, PDGFB, EGFR, PDGFRA, PDGFRB, JAK1, JAK2, JAK3, TYK2, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6, IRF9, CISH, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS7, SOCS6, BCL2, MCL1, BCL2L1, PIM1, MYC, CCND1, CCND2, CCND3, CDKN1A, AOX1, GFAP, STAM2, STAM, PTPN2, PTPN6, CREBBP, EP300, PIAS1, PIAS2, PIAS3, PIAS4, FHL1, PTPN11, GRB2, SOS1, SOS2, HRAS, RAF1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR
## 19 EGF, TGFA, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, NGF, BDNF, NTF3, NTF4, INS, IGF1, IGF2, PDGFA, PDGFB, PDGFC, PDGFD, CSF1, KITLG, FLT3LG, VEGFA, VEGFB, PGF, VEGFC, VEGFD, HGF, ANGPT1, ANGPT2, ANGPT4, EFNA1, EFNA2, EFNA3, EFNA4, EFNA5, EGFR, FGFR1, FGFR2, FGFR3, FGFR4, NGFR, NTRK1, NTRK2, INSR, IGF1R, PDGFRA, PDGFRB, CSF1R, KIT, FLT3, FLT1, FLT4, KDR, MET, TEK, EPHA2, GRB2, GAB1, GAB2, SHC1, SHC2, SHC3, SHC4, PTPN11, SOS1, SOS2, PLCG1, PLCG2, RASGRP1, RASGRP2, RASGRP3, RASGRP4, ZAP70, LAT, HTR7, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, PRKACA, PRKACB, PRKACG, RASGRF1, RASGRF2, GRIN1, GRIN2A, GRIN2B, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, HRAS, KRAS, NRAS, MRAS, RRAS, RRAS2, NF1, RASA1, RASA2, RASA3, RASA4, RASA4B, SYNGAP1, RASAL1, RASAL2, RASAL3, RASSF1, RASSF5, STK4, TIAM1, RAC1, RAC2, RAC3, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, RHOA, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, IKBKG, CHUK, IKBKB, NFKB1, RELA, BAD, BCL2L1, FOXO4, FASLG, RALGAPA1, RALGAPA2, RALGAPB, RALGDS, RGL1, RGL2, RALA, RALB, PLD1, PLD2, EXOC2, TBK1, REL, MAPK8, MAPK10, MAPK9, RALBP1, CDC42, AFDN, SHOC2, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PLA1A, PLA2G10, PLA2G2D, PLA2G2E, PLA2G3, PLA2G2F, PLA2G12A, PLA2G12B, PLA2G1B, PLA2G5, PLA2G2A, PLA2G2C, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PLA2G6, PLAAT3, PLAAT2, ELK1, ETS1, ETS2, BRAP, KSR1, KSR2, RAPGEF5, RAP1A, RAP1B, PLCE1, PRKCA, PRKCB, PRKCG, RIN1, ABL1, ABL2, RAB5A, RAB5B, RAB5C, ARF6
## 39 CACNA1A, CACNA1B, CACNA1C, CACNA1D, CACNA1E, CACNA1F, CACNA1G, CACNA1H, CACNA1I, CACNA1S, CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, CACNB1, CACNB2, CACNB3, CACNB4, CACNG1, CACNG2, CACNG3, CACNG4, CACNG5, CACNG6, CACNG7, CACNG8, PRKACA, PRKACB, PRKACG, PRKCA, PRKCB, PRKCG, GNA12, GNG12, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, RASGRF1, RASGRF2, RASGRP1, RASGRP2, RASGRP3, RASGRP4, RAPGEF2, NF1, RASA1, RASA2, RAP1A, RAP1B, EGF, TGFA, EREG, AREG, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, NGF, BDNF, NTF3, NTF4, INS, IGF1, IGF2, PDGFA, PDGFB, PDGFC, PDGFD, CSF1, KITLG, FLT3LG, VEGFA, VEGFB, PGF, VEGFC, VEGFD, HGF, ANGPT1, ANGPT2, ANGPT4, EFNA1, EFNA2, EFNA3, EFNA4, EFNA5, EGFR, ERBB2, ERBB3, ERBB4, FGFR1, FGFR2, FGFR3, FGFR4, NGFR, NTRK1, NTRK2, INSR, IGF1R, PDGFRA, PDGFRB, CSF1R, KIT, FLT3, FLT1, FLT4, KDR, MET, TEK, EPHA2, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RRAS, RRAS2, MRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, LAMTOR3, MAPK1, MAPK3, MKNK1, MKNK2, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, ATF4, ELK1, ELK4, MYC, SRF, FOS, MAPT, STMN1, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, TNF, IL1A, IL1B, TGFB1, TGFB2, TGFB3, TNFRSF1A, IL1R1, IL1RAP, TGFBR1, TGFBR2, FASLG, FAS, CD14, RAC1, RAC2, RAC3, CDC42, TRADD, CASP3, TRAF2, DAXX, MYD88, IRAK1, IRAK4, TRAF6, GADD45A, GADD45B, GADD45G, TAB1, TAB2, ECSIT, MAP4K3, MAP4K4, MAP4K1, PAK1, PAK2, STK4, STK3, MAP4K2, MAP3K8, MAP3K1, MAP3K11, MAP3K2, MAP3K3, MAP3K13, MAP3K12, MAP3K20, MAP3K6, MAP3K5, MAP3K7, MAP3K4, TAOK2, TAOK3, TAOK1, MAP2K4, MAP2K7, MAP2K3, MAP2K6, MAPK8IP1, MAPK8IP2, MAPK8IP3, FLNA, FLNC, FLNB, CRK, CRKL, ARRB1, ARRB2, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, MAPKAPK5, MAPKAPK2, MAPKAPK3, RPS6KA5, RPS6KA4, CDC25B, NFATC1, NFATC3, JUN, JUND, ATF2, TP53, DDIT3, MAX, MEF2C, HSPB1, AKT1, AKT2, AKT3, PPM1A, PTPRR, PTPN5, PTPN7, DUSP1, DUSP4, DUSP2, DUSP7, DUSP8, DUSP5, DUSP16, DUSP6, DUSP9, DUSP10, DUSP3, PPP5C, PPM1B, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, MECOM, MAP2K5, MAPK7, NR4A1, MAP3K14, CHUK, IKBKB, IKBKG, NLK, NFKB1, NFKB2, RELA, RELB
## 58 RAP1A, RAP1B, MRAS, RAPGEF5, DOCK4, GRIN1, GRIN2A, GRIN2B, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, F2R, F2RL3, P2RY1, FPR1, LPAR1, LPAR2, LPAR3, LPAR4, LPAR5, ADORA2A, ADORA2B, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, RAPGEF3, RAPGEF4, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, RASGRP3, RASGRP2, EGF, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, NGF, INS, IGF1, PDGFA, PDGFB, PDGFC, PDGFD, CSF1, KITLG, VEGFA, VEGFB, PGF, VEGFC, VEGFD, HGF, ANGPT1, ANGPT2, ANGPT4, EFNA1, EFNA2, EFNA3, EFNA4, EFNA5, EGFR, FGFR1, FGFR2, FGFR3, FGFR4, NGFR, INSR, IGF1R, PDGFRA, PDGFRB, CSF1R, KIT, FLT1, FLT4, KDR, MET, TEK, EPHA2, CRK, CRKL, RAPGEF1, BCAR1, CDH1, CTNNB1, MAGI1, MAGI2, MAGI3, RAPGEF2, RAPGEF6, LAT, FYB1, LCP2, SKAP1, PLCG1, PRKCA, PRKCB, PRKCG, PRKD1, PRKD3, PRKD2, DRD2, CNR1, GNAI1, GNAI3, GNAI2, GNAO1, RAP1GAP, SIPA1L1, SIPA1, SIPA1L2, SIPA1L3, ID1, THBS1, RALGDS, RALA, RALB, RAC1, RAC2, RAC3, APBB1IP, TLN1, TLN2, ITGA2B, ITGB3, PFN3, PFN1, PFN2, PFN4, VASP, ENAH, EVL, ACTG1, ACTB, ARAP3, RHOA, SRC, FARP2, CDC42, VAV3, VAV1, VAV2, TIAM1, PARD3, PARD6A, PARD6G, PARD6B, PRKCZ, PRKCI, AFDN, CTNND1, KRIT1, RGS14, RASSF5, ITGAL, ITGAM, ITGB2, ITGB1, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, PLCE1, HRAS, KRAS, NRAS, RRAS
## 20 INS, INSR, IGF1, IGF1R, IRS1, IRS2, IRS4, HRAS, KRAS, NRAS, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, ATF2, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, ATF4, CREB5, ATF6B, EHMT2, EHMT1, FOXO1, FOXO3, SOD2, CAT, ATG5, KL, TSC1, TSC2, RHEB, MTOR, RPTOR, AKT1S1, ULK1, ATG13, RB1CC1, ATG101, RPS6KB1, RPS6KB2, EIF4EBP1, EIF4E, EIF4E2, EIF4E1B, ADIPOQ, ADIPOR1, ADIPOR2, APPL1, CAMKK2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, SIRT1, BAX, TP53, NFKB1, RELA, PPARG, PPARGC1A, STK11, SESN1, SESN3, SESN2, CAMK4
## 25 INS, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, PPP1CA, PPP1CB, PPP1CC, PPP1R3A, PPP1R3C, PPP1R3D, PPP1R3B, PPP1R3E, INSR, IRS1, PTPN1, PTPN11, PTPRF, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, PRKCB, IL6, STAT3, SOCS3, GSK3B, GYS2, GYS1, TNF, TNFRSF1A, MAPK8, MAPK10, MAPK9, IKBKB, NFKBIA, NFKB1, RELA, NOS3, PRKCZ, TBC1D4, SLC2A4, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, ACACB, CPT1B, AGT, SLC27A1, SLC27A4, SLC27A2, SLC27A3, SLC27A5, SLC27A6, CD36, PRKCQ, PRKCD, PTPA, SREBF1, IRS2, TRIB3, PYGL, PYGM, PYGB, FOXO1, PCK1, PCK2, G6PC1, G6PC2, G6PC3, SLC2A2, NR1H3, NR1H2, PPARGC1B, MLX, MLXIP, MLXIPL, CPT1A, PRKCE, PPARGC1A, PPARA, PDPK1, PTEN, OGA, OGT, SLC2A1, GFPT2, GFPT1, CRTC2, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5
## 27 MAP3K7, STK11, CAB39, CAB39L, STRADA, STRADB, LEP, LEPR, CAMKK2, ADRA1A, ADIPOQ, ADIPOR1, ADIPOR2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, PFKFB1, PFKFB2, PFKFB3, PFKFB4, FBP1, FBP2, PFKM, PFKP, PFKL, HNF4A, G6PC1, G6PC2, G6PC3, PCK1, PCK2, CRTC2, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, PPARGC1A, ELAVL1, CCND1, CCNA2, CCNA1, EEF2K, EEF2, FOXO1, FOXO3, SIRT1, SLC2A4, GYS2, GYS1, LIPE, HMGCR, SREBF1, FASN, ACACA, SCD, SCD5, ACACB, MLYCD, CPT1A, CPT1B, CPT1C, CIDEA, PPP2CA, PPP2CB, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3B, PPP2R3C, PPP2R3A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PPP2R5A, TBC1D1, RAB2A, RAB8A, RAB10, RAB11B, RAB14, CFTR, CD36, IGF1, IGF1R, INS, INSR, IRS1, IRS2, IRS4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, TSC2, TSC1, RHEB, MTOR, RPTOR, AKT1S1, RPS6KB1, RPS6KB2, EIF4EBP1, PPARG, ULK1
## 29 AKT1, AKT2, AKT3, PDE3B, GCG, GCGR, GNAS, ADCY2, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, PPP4R3A, PPP4R3B, PPP4R3C, PPP4C, CRTC2, SIK2, CREBBP, EP300, PPARGC1A, SIK, SIK1, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, CAMK2A, CAMK2D, CAMK2B, CAMK2G, FOXO1, SIRT1, PPARA, PRMT1, G6PC1, G6PC2, G6PC3, PCK1, PCK2, CPT1A, CPT1B, CPT1C, GYS2, GYS1, PHKB, PHKA2, PHKA1, PHKG1, PHKG2, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PYGL, PYGM, PYGB, PFKFB1, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, ACACA, ACACB, SLC2A1, SLC2A2, GCK, FBP1, FBP2, PFKM, PFKP, PFKL, PGAM1, PGAM2, PGAM4, PKM, PDHA2, PDHA1, PDHB, LDHAL6A, LDHAL6B, LDHA, LDHB, LDHC
## 46 INS, INSR, IRS1, IRS2, IRS4, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, PDPK1, AKT1, AKT2, AKT3, GSK3B, GYS2, GYS1, PPP1CA, PPP1CB, PPP1CC, PPP1R3A, PPP1R3C, PPP1R3D, PPP1R3B, PPP1R3E, PPP1R3F, PHKG1, PHKG2, PHKB, PHKA2, PHKA1, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PYGL, PYGM, PYGB, PDE3B, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR2A, PRKAR2B, PRKAR1B, LIPE, PRKCZ, PRKCI, SLC2A4, FLOT2, FLOT1, SH2B2, SORBS1, CBL, CBLB, CRK, CRKL, RAPGEF1, RHOQ, EXOC7, TRIP10, SREBF1, ACACA, ACACB, FASN, PKLR, HK3, HK1, HK2, HKDC1, GCK, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, FOXO1, PPARGC1A, G6PC1, G6PC2, G6PC3, FBP1, FBP2, PCK1, PCK2, MTOR, RPTOR, RPS6KB1, RPS6KB2, RPS6, EIF4EBP1, EIF4E, EIF4E2, EIF4E1B, TSC1, TSC2, RHEB, BAD, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, MKNK1, MKNK2, ELK1, SOCS1, SOCS2, SOCS3, SOCS4, PTPN1, PTPRF, MAPK8, MAPK10, MAPK9, IKBKB, INPPL1, INPP5A
## 47 INS, INSR, IGF1, IGF1R, IRS1, IRS2, IRS4, HRAS, KRAS, NRAS, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, FOXO1, FOXO3, SOD2, CAT, ATG5, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, MTOR, RPTOR, AKT1S1, RPS6KB1, RPS6KB2, SIRT1, SOD1, EIF4EBP2, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, CRYAB, HDAC1, HDAC2, FOXA2, CLPB
## 61 C1QA, C1QB, C1QC, C2, C4A, C4B, C3, C3AR1, C5, C5AR1, LBP, CD14, LY96, TLR4, TIRAP, MYD88, IRAK4, IRAK1, TRAF6, TAB1, TAB2, MAP3K7, CHUK, IKBKB, IKBKG, NFKBIA, RELA, NFKB1, TNF, IL1B, IL6, IL12A, IL12B, CXCL8, TICAM1, TRAF3, IKBKE, TBK1, IRF3, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IL17A, IL17RA, IL17RC, CXCL1, CXCL2, CXCL3, FASLG, FAS, FADD, TNFRSF1A, TRADD, CASP8, CASP3, RIPK1, TAB3, SREBF1, FASN, ACACA, SCD, SCD5, LPIN1, LPIN3, LPIN2, MIR217, SIRT1, TRA2A, TRA2B, ADIPOQ, ADIPOR1, ADIPOR2, CAMKK2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, FOXO1, FOXO3, PPARGC1A, PPARA, CPT1A, ACADVL, ACADM, ACOX3, ACOX1, FABP1, ADH1A, ADH1B, ADH1C, ADH7, ADH4, ADH5, ADH6, ALDH2, ALDH3A2, ALDH1B1, ALDH7A1, ALDH9A1, CYP2E1, ACACB, MLYCD, CPT1B, CPT1C, NOX4, AKT1, AKT2, AKT3, GSK3B, CTNNB1, TCF7, TCF7L1, TCF7L2, LEF1, CCND1, MAP3K5, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAP3K14
## 71 TNF, TNFRSF1A, TRADD, TNFRSF1B, TRAF2, MTOR, MAPK8, MAPK10, MAPK9, CHUK, IKBKB, IKBKG, NFKBIA, NFKBIB, NFKBIE, NFKB1, RELA, SOCS3, IRS1, IRS2, IRS4, AKT1, AKT2, AKT3, CD36, ACSL6, ACSL4, ACSL1, ACSL5, ACSL3, ACSBG1, ACSBG2, PRKCQ, LEP, LEPR, JAK2, STAT3, POMC, AGRP, NPY, PPARGC1A, PCK1, PCK2, G6PC1, G6PC2, G6PC3, PTPN11, PPARA, RXRA, RXRB, RXRG, ADIPOQ, ADIPOR1, ADIPOR2, STK11, CAMKK2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, ACACB, CPT1A, CPT1B, CPT1C, SLC2A1, SLC2A4
## 22 SLC2A1, NRP1, MYC, TRRAP, KAT5, CCND2, ITGAL, ITGB2, ICAM1, HRAS, KRAS, NRAS, MAP2K1, MAP2K2, MAPK1, MAPK3, CD4, TLN1, TLN2, RANBP3, RAN, XPO1, CALR, CANX, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, IL2RB, IL2RG, JAK1, JAK3, STAT5A, STAT5B, IL2, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, B2M, FDPS, VDAC1, SLC25A4, SLC25A5, SLC25A6, SLC25A31, VDAC2, VDAC3, TSPO, VAC14, RANBP1, MAD1L1, MAD2L1, BUB1B, BUB3, ANAPC1, ANAPC2, CDC27, ANAPC4, ANAPC5, CDC16, ANAPC7, CDC23, ANAPC10, ANAPC11, CDC26, ANAPC13, ANAPC15, ANAPC16, CDC20, PTTG1, PTTG2, ESPL1, CCNB2, CDKN2B, CDKN2A, CDK4, CCND1, CCND3, CDKN1A, CCNA2, CCNA1, CCNE1, CCNE2, CDK2, RB1, E2F1, E2F2, E2F3, ATM, ATR, CHEK1, CHEK2, TP53, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, DLG1, PTEN, TNF, TNFRSF1A, MAP3K1, MAP2K4, MAPK8, MAPK10, MAPK9, JUN, MMP7, IL1R1, IL1R2, CD3D, CD3E, CD3G, MAP3K3, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, GPS2, LTBR, CD40, TNFRSF13C, MAP3K14, RELB, NFKB2, ZFP36, IL2RA, IL15, IL15RA, IL6, CSF2, LTA, BCL2L1, XIAP, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, NFYB, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, SRF, ELK4, ELK1, SPI1, ETS1, ETS2, TBPL2, TBPL1, TBP, FOS, EGR1, FOSL1, EGR2, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, ATF2, ATF4, CREB5, ATF6B, CRTC1, CRTC2, CRTC3, CREBBP, EP300, KAT2B, KAT2A, TCF3, POLB, LCK, BAX, CDKN2C, TERT, MSX1, MSX2
## 65 SRC, HRAS, KRAS, NRAS, MAPK1, MAPK3, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, DDB1, YWHAZ, YWHAB, YWHAQ, YWHAE, YWHAH, YWHAG, JAK1, STAT3, STAT5A, STAT5B, CASP3, HPN, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, RELA, REL, NFKB2, NFKB1, TP53, CCNE1, CCNE2, CDK2, EGR2, EGR3, VDAC3, LTBR, SP100, HNRNPK, CDKN1A, DDX3X, EIF2AK2, PRKACA, PRKACB, PRKACG, H2BC15, H2BC9, H2BC14, H2BW1, H2BC1, H2BC18, H2BC17, H2BC3, H2BC8, H2BC13, H2BC4, H2BC5, H2BC6, H2BC10, H2BC21, H2BC11, H2BC12, H2BC26, H2BC7, H2BW2, H2BK1, H2BC12L, H4C16, H4C15, H4C9, H4C4, H4C6, H4C12, H4C11, H4C3, H4C8, H4C2, H4C5, H4C13, H4C14, H4C1, H4C7, BAX, GRB2, TRADD, CDK1, TBPL2, TBPL1, TBP, USP7, MDM2, RBPJL, RBPJ, SNW1, GTF2H1, GTF2H2, GTF2H2C_2, GTF2H2C, GTF2H3, GTF2H4, GTF2E1, GTF2E2, SND1, CREBBP, EP300, GTF2B, CCND1, CCND2, CCND3, CDK6, CCNA2, CCNA1, SKP2, MRPS18B, TRAF1, TRAF2, TRAF3, TRAF5, JAK3, LYN, SYK, ATP6V0D1, ATP6V0D2, UBE3A, DLG1, SCRIB, PXN, BAK1, IRF3, PSMC1, RB1, RBL1, RBL2, CDKN1B, UBR4, JUN, CHD4, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HDAC10, HDAC11, PKM, IRF9, DNAJA3, KAT2B, KAT2A, GTF2A1L, GTF2A1, GTF2A2, SRF, IKBKG, NFKBIA, RASA2, CDC42, RAC1, RHOA, GSN, SCIN, ACTN1, ACTN4, CDK4, CDKN2A, CDKN2B, CHEK1, CDC20, MAD1L1, VAC14, RANBP1, POLB, IRF7, IL6ST, CCR5, CCR8, CCR3, CCR4, MAPKAPK2, CASP8, BAD, PMAIP1, C3, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E
## 26 CD36, SLC27A1, SLC27A4, SLC27A2, SLC27A5, SLC27A6, FABP1, FABP2, FABP3, FABP4, FABP5, FABP6, FABP7, PPARA, RXRA, RXRB, RXRG, PPARD, PPARG, HMGCS1, HMGCS2, APOA1, APOA2, APOC3, APOA5, PLTP, ME3, ME1, FADS2, SCD, SCD5, CYP7A1, CYP8B1, NR1H3, CYP27A1, DBI, LPL, ACSL6, ACSL4, ACSL1, ACSL5, ACSL3, ACSBG1, ACSBG2, OLR1, EHHADH, ACAA1, SCP2, ACOX3, ACOX1, ACOX2, CPT1A, CPT1B, CPT1C, CPT2, ACADL, ACADM, ANGPTL4, SORBS1, PLIN1, PLIN2, PLIN4, PLIN5, ADIPOQ, MMP1, UCP1, ILK, PDPK1, UBC, PCK1, PCK2, GK2, GK, AQP7, AQP7B
## 147 ACAT2, ACAT1, ACAA1, ACAA2, HADHB, HADH, HADHA, EHHADH, ECHS1, ACOX3, ACOX1, ACADS, ACADM, ACADL, ACADSB, ACADVL, GCDH, ACSL6, ACSL4, ACSL1, ACSL5, ACSL3, ACSBG1, ACSBG2, CPT1A, CPT1B, CPT1C, CPT2, ECI1, ECI2, CYP2U1, ADH1A, ADH1B, ADH1C, ADH7, ADH4, ADH5, ADH6, ALDH2, ALDH3A2, ALDH1B1, ALDH7A1, ALDH9A1
## 28 PODXL, PTPRC, RAB5A, RAB5B, RAB5C, PIK3C3, RAB7A, RAB7B, PLEKHM1, VPS11, VPS16, VPS18, VPS33A, VPS39, VPS41, RILP, DYNC1H1, DYNC2H1, DYNC1I1, DYNC1I2, DYNC1LI2, DYNC1LI1, DYNC2LI1, DYNLL1, DYNLL2, DYNLRB1, DYNLRB2, DYNLT1, DYNLT3, DCTN1, DCTN2, DCTN3, DCTN4, DCTN5, DCTN6, ACTR1A, ACTR1B, ACTR10, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3, TUBB6, TUBB, TUBB1, TUBB2A, TUBB3, TUBB4A, TUBB8, TUBB2B, TUBB4B, FYCO1, ARL8A, ARL8B, PLEKHM2, KIF5A, KIF5B, KIF5C, KLC3, KLC1, KLC2, KLC4, ACBD3, RHOA, M6PR, RAB9A, RAB9B, GCC2, STX10, PFN3, PFN1, PFN2, PFN4, FLNA, FLNC, FLNB, EXOC7, EXOC5, EXOC4, EXOC2, RALA, ACTG1, ACTB, S100A10, ANXA2, AHNAK, AHNAK2, RHOJ, ARHGEF26, RHOG, ELMO1, ELMO2, ROCK2, MYL2, MYL5, MYL7, MYL9, MYL10, MYL12B, MYL12A, MYL11, FHOD1, CDC42, RAC1, NCKAP1, NCKAP1L, CYFIP1, CYFIP2, ABI1, BRK1, WASF3, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, PAK1, PAK3, MYO6, PIK3CA, PIK3CD, PIK3CB, PIK3CG, PIK3C2G, PIK3C2A, PIK3C2B, CYTH3, CYTH4, CYTH2, CYTH1, ARF6, ARF1, SNX18, SNX33, SNX9, WASL, DNM2, TLR6, TLR2, TIRAP, MYD88, CD14, TLR4, LY96, TLR5, TLR9, IRAK1, IRAK4, TRAF6, MAP3K7, TAB1, TAB2, TAB3, IKBKG, CHUK, IKBKB, NFKBIA, NFKB1, RELA, NOD1, HSP90AA1, HSP90AB1, HSP90B1, RIPK2, CSE1L, KPNA1, KPNA3, KPNA4, RPS3, HRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, FOS, JUN, TNF, IL1B, IL6, CXCL8, CTNNB1, TCF7, TCF7L1, TCF7L2, LEF1, MYC, PKN1, FBXO22, SKP1, TNFRSF1A, TRAF2, TRADD, BIRC2, BIRC3, RIPK1, GAPDH, TNFSF10, TNFRSF10A, TNFRSF10B, FADD, CASP8, RIPK3, BAX, BAK1, CYCS, BCL2, CASP3, CASP7, RHOB, RHOH, RRAS, AKT1, AKT2, AKT3, MLKL, TXN, TXN2, NLRP3, NAIP, NLRC4, PYCARD, CASP1, IL18, CASP4, CASP5, GSDMD
## 49 CD44, ITGA5, ITGB1, SRC, PTK2, CRK, CRKL, BCAR1, CTTN, HCLS1, PXN, ELMO1, ELMO2, DOCK1, RAC1, WASF1, WASF2, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, ACTG1, ACTB, RHOA, DIAPH1, ROCK1, ROCK2, MYL2, MYL5, MYL7, MYL9, MYL10, MYL12B, MYL12A, MYL11, ACTN1, ACTN4, ILK, TLN1, TLN2, VCL, CDC42, WASL, PFN3, PFN1, PFN2, PFN4, EGFR, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, CYTH3, CYTH4, CYTH2, CYTH1, ARF6, ARF1, AKT1, AKT2, AKT3, FOXO1, FOXO3, FOXO4, FOXO6, GSK3A, GSK3B, RPS6KB1, RPS6KB2, MDM2, PLCB1, PLCB2, PLCB3, PLCB4, PLCD1, PLCD3, PLCD4, PLCE1, PLCG1, PLCG2, PLCZ1, ITPR1, ITPR2, ITPR3, CAST, CAPN1, CAPN2, CAPNS1, ATM, TP53, BCL2L1, BCL2, HK3, HK1, HK2, HKDC1, VDAC1, BAX, CYCS, BNIP3, PPID, CASP4, IL1B, IL18, TNF, TNFRSF1A, TRADD, TRAF2, TRAF5, RIPK1, MAP3K7, TAB1, TAB2, TAB3, IKBKG, CHUK, IKBKB, NFKBIA, NFKBIB, NFKB1, RELA, CXCL8, TIFA, IL1R1, CD14, TLR4, TLR5, TRAF6, PRKCD, PRKCE, PRKCQ, MALT1, BCL10, NOD1, ARHGEF2, RIPK2, MAPK8, MAPK10, MAPK9, JUN, UBE2V1, UBE2V2, UBE2NL, UBE2N, RBCK1, RNF31, SHARPIN, TNIP1, UBE2D4, UBE2D1, UBE2D2, UBE2D3, RBX1, CUL1, SKP1, BTRC, FBXW11, CGAS, STING1, MYD88, TBK1, IRF3, IFNB1, U2AF1, U2AF1L5, U2AF1L4, CCL5, CSF2, MAPK1, MAPK3, MAPK11, MAPK12, MAPK13, MAPK14, RPS6KA5, H3-5, H3-3B, H3C4, H3C3, H3C1, H3-3A, H3-4, H3C14, H3C15, H3C13, H3C6, H3C11, H3C8, H3C12, H3C10, H3C2, H3C7, CBX3, BECN1, BECN2, ATG14, PIK3R4, PIK3C3, RRAGA, RRAGB, RRAGC, RRAGD, MTOR, RPTOR, AKT1S1, ATG16L1, ATG5, ATG12, MAP1LC3C, MAP1LC3B, MAP1LC3A, MAP1LC3B2, C3, SQSTM1, CALCOCO2, UBA52, RPS27A, UBB, UBC, SEPTIN2, SEPTIN9, SEPTIN12, SEPTIN3, SEPTIN6, SEPTIN11, SEPTIN8, SEPTIN7, WIPI2, WIPI1, TECPR1, FNBP1, FNBP1L, GLMN, NLRP3, NAIP, NLRC4, PYCARD, CASP1
## 57 FN1, ITGA4, ITGA5, ITGB1, RHOG, SRC, PTK2, PTK2B, CRK, CRKL, BCAR1, ELMO1, ELMO2, DOCK1, IGH, FCGR2A, RAC1, RAC2, RAC3, PIP5K1C, PIP5K1A, PIP5K1B, ARF6, WASL, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, ACTG1, ACTB, WIPF2, WIPF1, WIPF3, BAIAP2, WASF2, PXN, GIT2, ARHGEF7, CDC42, WAS, GNAQ, ARHGEF12, ARHGEF1, ARHGEF28, RHOA, ROCK1, ROCK2, FYB1, SKAP2, NLRP3, NLRC4, PKN1, PKN2, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, MEFV, LIMK1, PYCARD, CASP1, IL18, IL1B, TLR4, MYD88, IRAK4, IRAK1, TRAF6, TRAF2, TAB1, TAB2, MAP3K7, IKBKG, CHUK, IKBKB, NFKBIA, NFKB1, RELA, MAP2K1, MAP2K2, MAPK1, MAPK3, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, FOS, JUN, TICAM1, TBK1, IRF3, TNF, IL6, CXCL8, IFNB1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, GSK3B, CCL2, CD4, CD8A, CD8B, CD8B2, LCK, ZAP70, LAT, LCP2, VAV3, VAV1, VAV2, PLCG1, NFATC1, NFATC2, NFATC3, IL2, IL10
## 74 IGH, SRC, FCGR2A, RAC1, CYTH3, CYTH4, CYTH2, CYTH1, ARF6, ARF1, NCKAP1, NCKAP1L, CYFIP1, CYFIP2, ABI1, BRK1, WASF1, WASF2, WASF3, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, ACTG1, ACTB, ARHGEF1, RHOA, CDC42, MYO1H, MYO1B, MYO1F, MYO1A, MYO1C, MYO1D, MYO1E, MYO1G, MYO5A, MYO5B, MYO5C, MYO6, MYO10, MYH9, MYH10, MYH11, MYH14, WASL, NHERF1, EZR, F2, LPAR1, LPAR2, LPAR4, LPAR5, F2R, GNA12, GNA13, ARHGEF11, ARHGEF12, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3, TUBB6, TUBB, TUBB1, TUBB2A, TUBB3, TUBB4A, TUBB8, TUBB2B, TUBB4B, ARHGEF2, ROCK1, ROCK2, FYN, ABL1, BAIAP2L1, BAIAP2, NCK1, NCK2, WIPF2, WIPF1, WIPF3, CTTN, HCLS1, NCL, ITGB1, IL1B, IL1R1, TLR4, TIRAP, MYD88, TLR5, IRAK1, IRAK4, PTPN6, PTPN11, TRAF6, TNF, TNFRSF1A, TRADD, GAPDH, TRAF2, RIPK1, MAP3K7, TAB1, TAB2, TAB3, IKBKG, CHUK, IKBKB, NFKBIA, NFKBIB, NFKB1, RELA, RPS3, MAPK1, MAPK3, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, FOS, JUN, IL6, CXCL8, TNFSF10, TNFRSF10A, TNFRSF10B, FASLG, FAS, FADD, CASP8, TMBIM6, BAK1, BAX, CYCS, CASP9, CASP3, CASP7, ABCF2, NAIP, NLRP4, NLRP3, PYCARD, CASP1, CASP4, IL18, PAK1, PAK2, PAK3, RAB1A, SEC24B, SEC24A, SEC24C, SEC24D, TMED10, OCLN, CLDN4, CLDN3, CLDN7, CLDN19, CLDN16, CLDN14, CLDN15, CLDN17, CLDN20, CLDN11, CLDN18, CLDN22, CLDN5, CLDN10, CLDN8, CLDN6, CLDN2, CLDN1, CLDN9, CLDN23, CLDN34, CLDN25, CLDN24, TJP1
## 30 TNF, TNFRSF1A, BAG4, TRADD, TRAF2, TRAF5, RIPK1, BIRC2, BIRC3, MAP3K7, TAB1, TAB2, TAB3, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, JUN, FOS, ITCH, CFLAR, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, CEBPB, MAP3K5, MAP3K14, IKBKG, IKBKB, CHUK, NFKBIA, RELA, NFKB1, MAP3K8, MAP2K1, MAPK1, MAPK3, RPS6KA5, RPS6KA4, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, ATF2, ATF4, CREB5, ATF6B, RIPK3, MLKL, PGAM5, DNM1L, FADD, CASP8, CASP10, CASP7, CASP3, CCL2, CCL5, CCL20, CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL10, CX3CL1, CSF1, CSF2, FAS, IL18R1, JAG1, IL1B, IL6, IL15, LIF, LTA, BCL3, SOCS3, TNFAIP3, TRAF1, JUNB, MMP3, MMP9, MMP14, EDN1, VEGFC, VEGFD, NOD2, ICAM1, SELE, VCAM1, PTGS2, TNFRSF1B, TRAF3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, DAB2IP, IRF1, IFNB1
## 31 CD4, BTRC, FBXW11, SKP1, CUL1, RBX1, CXCR4, CCR5, GNAI1, GNAI3, GNAI2, GNAO1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTK2, PTK2B, PXN, CRK, CRKL, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, NFKB1, RELA, FOS, JUN, BAD, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, GNAQ, GNA11, PLCG1, PLCG2, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, PRKCA, PRKCB, PRKCG, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, RAC1, RAC2, RAC3, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, LIMK1, LIMK2, CFL1, CFL2, TNF, TNFRSF1B, BCL2L1, TLR2, TLR4, MYD88, IRAK4, IRAK1, TRAF6, TAB1, TAB2, MAP3K7, CHUK, IKBKB, IKBKG, NFKBIA, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, CGAS, STING1, TBK1, IRF3, APOBEC3H, APOBEC3F, APOBEC3A_B, APOBEC3D, APOBEC3A, APOBEC3C, APOBEC3G, APOBEC3B, SAMHD1, TRIM5, BST2, TNFRSF1A, RIPK1, TRADD, TRAF5, TRAF2, MAP2K3, MAP2K6, MAP2K7, FASLG, FAS, FADD, CASP8, BID, BAX, BAK1, BCL2, CYCS, CASP9, CASP3, CD3E, CD3G, CD3D, CD247, TAP1, TAP2, TAPBP, PDIA3, CALR, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, AP1B1, AP1G1, AP1G2, AP1M1, AP1M2, AP1S1, AP1S2, AP1S3, B2M, ELOB, ELOC, CUL5, RNF7, DCAF1, DDB1, CUL4B, CUL4A, ATM, ATR, CHEK1, CDC25C, WEE1, WEE2, CCNB1, CCNB2, CCNB3, CDK1
## 37 PDGFRA, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, TSC1, TSC2, RHEB, MTOR, EIF4EBP1, RPS6KB1, RPS6KB2, CHUK, IKBKB, IKBKG, NFKB1, RELA, EGFR, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, ELK1, SP1, ITGAV, ITGB3, SRC, RAC1, RAC2, RAC3, RHOA, CGAS, STING1, TBK1, IRF3, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, TNF, TNFRSF1A, RIPK1, TRADD, TRAF5, TRAF2, IL1B, IL1R1, NFKBIA, CCL2, CCL5, CXCL8, IL6, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, PTGS2, GNAI1, GNAI3, GNAI2, GNAO1, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CCL3, CCL3L1, CCL3L3, CCL4, CCL4L2, CCL4L1, CX3CL1, GNA12, GNA13, ARHGEF1, ARHGEF11, ARHGEF12, AKAP13, ROCK1, ROCK2, CTNNB1, PTGER1, PTGER2, PTGER3, PTGER4, GNAS, GSK3B, CCND1, MYC, IL6R, JAK1, STAT3, VEGFA, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, CXCL12, CXCR4, PRKCA, PRKCB, PRKCG, PTK2B, PTK2, BCAR1, CRK, CRKL, PXN, IL10RA, IL10RB, CXCR2, CCR1, CCR3, CCR5, TAP1, TAP2, TAPBP, PDIA3, CALR, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, B2M, CDKN2A, MDM2, TP53, CDKN1A, CDK4, CDK6, RB1, E2F1, E2F2, E2F3, FASLG, FAS, FADD, CASP8, BID, BAX, BAK1, CYCS, CASP9, CASP3
## 45 CSF1, CSF1R, GRB2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, IFNG, IFNGR1, IFNGR2, STAT1, IL1A, IL1B, IL1R1, TNF, TNFRSF1A, TGFB1, TGFB2, TGFBR1, TGFBR2, TNFSF11, TNFRSF11A, TNFRSF11B, TRAF2, TRAF6, LCK, FYN, MAP3K14, CHUK, RELB, NFKB2, MAP3K7, TAB1, TAB2, IKBKG, IKBKB, NFKBIA, RELA, NFKB1, NFATC2, NFATC1, IFNB1, MAP2K1, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAP2K7, MAPK8, MAPK10, MAPK9, FOS, FOSB, FOSL2, FOSL1, JUN, JUND, JUNB, RAC1, NOX1, CYBA, NCF2, NCF1, NCF4, BTK, TEC, OSCAR, LILRB2, LILRB1, LILRB5, LILRB4, LILRA1, LILRB3, LILRA3, LILRA2, LILRA4, LILRA6, LILRA5, FCGR1A, FCGR2A, FCGR2B, FCGR2C, FCGR3A, FCGR3B, TREM2, SIRPA, SIRPG, SIRPB1, TYROBP, SYK, BLNK, LCP2, PLCG2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, CAMK4, CREB1, SPI1, MITF, CTSK, ACP5, CALCR, ITGB3, PPARG, IFNAR1, IFNAR2, JAK1, TYK2, STAT2, IRF9, SOCS1, SOCS3, GAB2, FHL2, CYLD, SQSTM1
## 52 APOB, APOA4, APOA1, LDLR, OLR1, ARHGEF1, MMP1, RHOA, ROCK2, NOS3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BAX, BAD, BCL2L1, BCL2, MAPK8, MAPK10, MAPK9, SOD2, PRKCA, POU2F1, POU2F2, POU2F3, CD40, CD40LG, CYP1A1, CYP2A6, CYP2A7, CYP2B6, CYP2C8, CYP2C9, CYP2J2, AGER, NOX1, CYBB, NCF1, CYBA, NCF2, NCF4, RAC1, SRC, JAK2, STAT3, CDC42, MAP2K4, MAP2K7, FOS, JUN, CCL2, ICAM1, CXCL8, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, HRAS, KRAS, NRAS, MAPK1, MAPK3, RELA, NFKB1, SELE, SELP, VCAM1, MMP3, MMP9, FAS, IL1B, IL6, TNF, HSPD1, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, HSPA4, HSP90AA1, HSP90AB1, HSP90B1, TLR2, LBP, CD14, LY96, TLR4, TIRAP, MYD88, IRAK4, IRAK1, TRAF6, TAB1, TAB2, MAP3K7, CHUK, IKBKB, IKBKG, NFKBIA, TICAM2, TICAM1, TRAF3, MIB1, MIB2, TANK, IKBKE, TBK1, IRF7, IRF3, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, CD36, PPARG, RXRA, RXRB, RXRG, LYN, PTK2, VAV3, VAV1, VAV2, TLR6, RAP1A, RAP1B, CCL5, CCL3, CCL3L1, CCL3L3, CXCL1, CXCL2, CXCL3, IL12A, IL12B, NLRP3, IL18, HSPA5, ATF6, DDIT3, ERO1A, ITPR1, CAMK2A, CAMK2D, CAMK2B, CAMK2G, EIF2AK3, EIF2S1, ATF4, ERN1, TRAF2, MAP3K5, XBP1, ABCA1, ABCG1, NFE2L2, PYCARD, CASP1, VLDLR, PDPK1, GSK3B, NFATC1, NFATC2, NFATC3, PLCB1, PLCB2, PLCB3, PLCB4, PLCG1, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, TNFSF10, TNFRSF10A, TNFRSF10B, TNFRSF1A, FASLG, CASP8, BID, CYCS, APAF1, CASP9, CASP6, CASP3, CASP7, TP53
## 73 C3, TLR3, TICAM1, TRAF3, IKBKE, TBK1, IRF7, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IRF3, CREBBP, EP300, IFNB1, IFNAR1, IFNAR2, JAK1, TYK2, STAT1, STAT2, IRF9, EIF2AK2, MAPK11, MAPK12, MAPK13, MAPK14, MAPKAPK2, MAP2K6, ZFP36, IL6, CSF2, CCR3, CCR5, CCR1, CCR4, CCR8, FAS, FADD, CASP8, BID, BAX, BAK1, CYCS, CASP9, CASP3, TNFRSF1A, TRADD, TRAF2, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, TP53, CDKN1A, CDK4, CDK6, RB1, E2F1, E2F2, E2F3, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, IFNGR1, ICAM1, CD86, MICB, MICA, CLEC2B, UBA52, RPS27A, UBB, UBC, BECN1, BECN2, ATG14, PIK3C3, ATG3, MAP1LC3C, MAP1LC3B, MAP1LC3A, MAP1LC3B2, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, HIF1A, JUN, FOS, PIK3CG, PIK3R5, PIK3R6, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, PREX1, RAC1, MAPK8, MAPK10, MAPK9, CD200R1L, CD200R1, SYK, SRC, HCK, LYN, MAP2K4, MAP2K7, PLCG2, PLCG1, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, CXCL8, PTGS2, CXCL1, CXCL2, CXCL3, RCAN1, FGF2, VEGFA, PDGFB, ANGPT2, IL6ST, JAK2, STAT3, GSK3B, CTNNB1, TCF7, TCF7L1, TCF7L2, LEF1, CREB1, CCND1, MYC
## 85 TNFSF10, TNFRSF10A, TNFRSF10B, FASLG, FAS, FADD, TNF, TNFRSF1A, TRADD, CFLAR, CASP8, CASP10, CASP6, CASP3, CASP7, BID, BAX, BAK1, DIABLO, SEPTIN4, HTRA2, CYCS, APAF1, CASP9, PRF1, GZMB, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3, MCL1, ACTG1, ACTB, SPTA1, SPTAN1, LMNA, LMNB1, LMNB2, PARP1, PARP2, PARP3, PARP4, DFFA, DFFB, ENDOG, AIFM1, ERN1, TRAF2, ITPR1, ITPR2, ITPR3, CAPN1, CAPN2, CASP12, EIF2AK3, EIF2S1, ATF4, DDIT3, CTSB, CTSC, CTSD, CTSF, CTSH, CTSK, CTSL, CTSO, CTSS, CTSV, CTSW, CTSZ, BIRC2, BIRC3, XIAP, BIRC5, BCL2L11, BCL2L1, BCL2, DAXX, RIPK1, DAB2IP, MAP3K5, MAPK8, MAPK10, MAPK9, BAD, JUN, FOS, TP53, HRK, MAP3K14, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, PTPN13, GADD45A, GADD45B, GADD45G, TRAF1, BCL2A1, ATM, PIDD1, TP53AIP1, BBC3, PMAIP1, CASP2, NGF, NTRK1, IL3, IL3RA, CSF2RB, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3
## 32 LCK, ZAP70, LAT, PLCG1, PRKCQ, IGH, SYK, LYN, BLNK, BTK, PLCG2, PRKCB, CARD10, CARD11, CARD14, BCL10, MALT1, IL1B, IL1R1, MYD88, IRAK1, IRAK4, TRAF6, TNF, TNFRSF1A, RIPK1, TRADD, TRAF2, TRAF5, BIRC2, BIRC3, EDA, EDAR, EDARADD, CYLD, EDA2R, RIGI, TRIM25, LBP, CD14, TLR4, LY96, TIRAP, TICAM2, TICAM1, CD40LG, CD40, TRAF3, TNFSF11, TNFRSF11A, LTA, LTB, TNFSF14, LTBR, MAP3K14, MAP3K7, TAB1, TAB2, TAB3, TNFSF13B, TNFRSF13C, IKBKG, CHUK, IKBKB, PARP1, PIAS4, UBE2I, ATM, PIDD1, ERC1, NFKBIA, NFKB1, RELA, CFLAR, XIAP, BCL2L1, BCL2, GADD45A, GADD45B, GADD45G, TRAF1, BCL2A1, NFKB2, CXCL8, TNFAIP3, PTGS2, CCL4, CCL4L2, CCL4L1, CXCL1, CXCL2, CXCL3, VCAM1, PLAU, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, RELB, CCL13, CCL19, CCL21, CXCL12, ICAM1
## 33 TH, DDC, SLC18A1, SLC18A2, DRD1, DRD5, CALY, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, PPP3CA, PPP3CB, PPP3CC, PRKCA, PRKCB, PRKCG, FOS, GNAS, GNAL, ADCY5, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, PPP1R1B, PPP1CA, PPP1CB, PPP1CC, SCN1A, CACNA1C, CACNA1D, CACNA1A, CACNA1B, KCNJ3, KCNJ6, KCNJ9, KCNJ5, DRD3, DRD4, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, DRD2, ARRB1, ARRB2, PPP2CA, PPP2CB, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3B, PPP2R3C, PPP2R3A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PPP2R5A, AKT1, AKT2, AKT3, GSK3A, GSK3B, GRIN2A, GRIN2B, GRIA1, GRIA2, GRIA3, GRIA4, KIF5A, KIF5B, KIF5C, CLOCK, BMAL1, SLC6A3, MAOB, MAOA, COMT, LRTOMT
## 55 RLN1, RLN2, RXFP1, GNAO1, GNAI1, GNAI3, GNAI2, GNAS, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, ADCY5, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, VEGFA, VEGFB, VEGFC, VEGFD, NFKBIA, NFKB1, RELA, NOS2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PRKCZ, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, MMP2, MMP9, AKT1, AKT2, AKT3, NOS3, NOS1, EDN1, EDNRB, MMP1, MMP13, TGFB1, TGFBR1, TGFBR2, SMAD2, ACTA2, COL1A1, COL1A2, COL3A1, COL4A2, COL4A4, COL4A6, COL4A1, COL4A5, COL4A3, INSL3, RXFP2, RLN3, RXFP3, ADCY1, ADCY2, ADCY3, ADCY4, ADCY6, ADCY7, ADCY8, ADCY9, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, MAP2K4, MAP2K7, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, JUN, FOS, HRAS, KRAS, NRAS, SRC, SHC1, SHC2, SHC3, SHC4, SOS1, SOS2, ARRB1, ARRB2, EGFR, GRB2, INSL5, RXFP4, GNA15
## 56 TSHB, CGA, TSHR, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, TTF1, TTF2, PAX8, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, TG, HSPA5, HSP90B1, CANX, PDIA4, ASGR1, ASGR2, ITPR1, ITPR2, ITPR3, SLC5A5, SLC26A4, TPO, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, IYD, DUOXA2, DUOX1, DUOX2, GPX6, GPX7, GPX2, GPX3, GPX1, GPX5, GPX8, GSR, ALB, TTR, SERPINA7, LRP2
## 60 ADRB1, ADRB2, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, SLC9A1, KCNQ1, KCNE1, KCNE1B, ATP2B1, ATP2B3, ATP2B4, ATP2B2, SLC8A1, SLC8A2, SLC8A3, SCN5A, SCN7A, SCN1B, SCN4B, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNB1, CACNB2, CACNB3, CACNB4, CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, CACNG1, CACNG2, CACNG3, CACNG4, CACNG5, CACNG6, CACNG7, CACNG8, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, RYR2, PPP2CA, PPP2CB, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3B, PPP2R3C, PPP2R3A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PPP2R5A, PPP1CA, PPP1CB, PPP1CC, TNNC1, TNNI3, TNNT2, TPM1, TPM2, TPM3, TPM4, ACTC1, MYH7, MYH6, MYL2, MYL3, MYL4, PLN, ATP2A1, ATP2A3, ATP2A2, AGT, AGTR1, AGTR2, ADRA1A, ADRA1B, ADRA1D, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PPP1R1A, MAPK1, MAPK3, RPS6KA5, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, CREM, BCL2, RAPGEF3, RAPGEF4, MAPK11, MAPK12, MAPK13, MAPK14, GNAI1, GNAI3, GNAI2, PIK3CG, PIK3R5, PIK3R6, AKT1, AKT2, AKT3
## 64 GHRH, GHRHR, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, ADCY10, SST, SSTR1, SSTR2, SSTR3, SSTR5, GNAI1, GNAI3, GNAI2, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, CREBBP, EP300, POU1F1, FOS, GH1, GH2, CSH1, CSH2, GHRL, GHSR, MRAP2, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, ITPR1, ITPR2, ITPR3, CACNA1S, CACNA1C, CACNA1D, CACNA1F, GHR, JAK2, PLCG1, PLCG2, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, STAT1, STAT3, STAT5A, STAT5B, IRS1, IRS2, IRS4, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, MTOR, GSK3B, IGF1, JUNB, SOCS1, SOCS2, SOCS3, IGFALS, IGFBP3, PTK2, BCAR1, CRK, CRKL, MAP3K1, MAP2K3, MAP2K4, MAP2K6, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14
## 68 SLC2A1, SLC2A2, GCK, TRPM4, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, ABCC8, KCNJ11, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CAMK2A, CAMK2D, CAMK2B, CAMK2G, KCNMA1, KCNU1, KCNMB1, KCNMB2, KCNMB3, KCNMB4, KCNN1, KCNN2, KCNN3, KCNN4, GCG, GLP1R, GIP, GPR119, ADCYAP1, ADCYAP1R1, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, PDX1, INS, RAPGEF4, RIMS2, PCLO, RAB3A, CCK, CCKAR, CHRM3, FFAR1, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR3, RYR2, VAMP2, STX1A, SNAP25, PRKCA, PRKCB, PRKCG
## 76 CHAT, ACHE, SLC18A3, CHRM1, CHRM3, CHRM5, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5, KCNJ2, KCNJ12, KCNJ18, KCNJ4, KCNJ14, CHRM2, CHRM4, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, KCNJ3, KCNJ6, PIK3CG, PIK3R5, PIK3R6, HRAS, KRAS, NRAS, MAP2K1, MAPK1, MAPK3, FOS, CHRNA7, CHRNA4, CHRNB2, CHRNA3, CHRNB4, CHRNA6, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, JAK2, FYN, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BCL2, CACNA1A, CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S, SLC5A7
## 82 AGT, AGTR1, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, PRKCE, PRKD1, PRKD3, PRKD2, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, ATF1, DAGLA, DAGLB, KCNK3, KCNK9, KCNJ5, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, CACNA1G, CACNA1H, CACNA1I, CACNA1C, CACNA1D, CACNA1F, CACNA1S, ORAI1, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK1D, CAMK1G, CAMK1, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, ATP2B1, ATP2B3, ATP2B4, ATP2B2, LIPE, LDLR, SCARB1, POMC, MC2R, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CYP11B2, STAR, NR4A2, NR4A1, CYP11A1, HSD3B1, HSD3B2, CYP21A2, NPPA, NPR1, PDE2A
## 95 CASR, GNAI1, GNAI3, GNAI2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, GCM1, GCM2, MAFB, GATA3, SP1, VDR, RXRA, RXRB, RXRG, FGF23, FGFR1, KL, MAPK1, MAPK3, EGR1, PTH, PTHLH, PTH1R, ARRB1, ARRB2, ARAF, BRAF, RAF1, MAP2K1, PRKCA, PRKCB, PRKCG, TRPV5, SLC34A1, SLC34A2, SLC34A3, NHERF1, GNAS, PDE4A, PDE4B, PDE4C, PDE4D, PRKACA, PRKACB, PRKACG, CYP27B1, CYP24A1, MEF2A, MEF2C, MEF2D, SOST, NR4A2, NACA, JUND, BGLAP, LRP5, LRP6, CREB1, ATF2, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, ATF4, CREB5, ATF6B, TNFSF11, BCL2, CDKN1A, FOS, RUNX2, MMP13, GNA12, GNA13, ARHGEF1, ARHGEF11, AKAP13, RHOA, PLD1, PLD2, MMP14, MMP15, MMP16, MMP17, MMP24, MMP25, HBEGF, EGFR
## 101 ESR1, ESR2, HSP90AA1, HSP90AB1, HSP90B1, FKBP4, FKBP5, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, NCOA1, NCOA2, NCOA3, BCL2, EBAG9, KRT9, KRT10, KRT12, KRT13, KRT14, KRT15, KRT16, KRT17, KRT18, KRT19, KRT31, KRT32, KRT33A, KRT33B, KRT34, KRT35, KRT40, KRT39, KRT23, KRT25, KRT28, KRT24, KRT27, KRT20, KRT38, KRT37, KRT36, KRT26, CTSD, TFF1, PGR, TGFA, RARA, FOS, JUN, SP1, GPER1, GNAS, SRC, MMP2, MMP9, HBEGF, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, EGFR, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, GABBR1, GABBR2, GNAI1, GNAI3, GNAI2, GNAO1, KCNJ3, KCNJ6, KCNJ9, KCNJ5, POMC, OPRM1, PRKCD, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, NOS3, GRM1
## 111 POMC, MC2R, MRAP, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PDE8B, PDE8A, PRKACA, PRKACB, PRKACG, NR0B1, NR5A1, NR4A1, SP1, PBX1, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, CYP11B1, CYP17A1, STAR, NCEH1, AGT, AGTR1, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, KCNK2, CACNA1G, CACNA1H, CACNA1I, CACNA1C, CACNA1D, CACNA1F, CACNA1S, ORAI1, KCNA4, KCNK3, LDLR, SCARB1, CYP11A1, HSD3B1, HSD3B2, CYP21A2
## 121 KISS1, KISS1R, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, ITPR1, ITPR2, ITPR3, HCN1, HCN2, HCN3, CACNA1G, CACNA1H, CACNA1I, TRPC1, TRPC4, TRPC5, KCNJ11, KCNJ3, KCNJ6, KCNJ9, KCNJ5, GABBR1, GABBR2, KCNN1, KCNN2, KCNN3, KCNN4, CACNA1S, CACNA1C, CACNA1D, CACNA1F, ARRB1, ARRB2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, GNRH1, GNRH2, ESR2, GPER1, LHB, SPP1, CGA
## 133 AGTR1, EDNRA, EDNRB, ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, GNAQ, GNA11, GNA12, GNA13, TRPC6, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, MEF2A, BORCS8-MEF2B, MEF2B, MEF2C, MEF2D, NFATC1, NFATC2, NFATC3, NFATC4, SRF, GATA4, MYH7, MYH6, NPPB, NPPA, NPR1, NPPC, NPR2, PRKG1, PRKG2, CACNA1C, CACNA1D, CACNA1F, CACNA1S, KCNMA1, KCNU1, KCNMB1, KCNMB2, KCNMB3, KCNMB4, SLC8A1, SLC8A2, SLC8A3, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, ATP2B1, ATP2B3, ATP2B4, ATP2B2, RGS2, GTF2IRD1, GTF2I, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, IRAG1, PLN, ATP2A1, ATP2A3, ATP2A2, RHOA, ROCK1, ROCK2, PPP1R12A, PPP1CA, PPP1CB, PPP1CC, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, MYLK, MYLK2, MYLK3, MYLK4, MYL9, CNGA1, CNGB1, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PDE2A, PDE3A, PDE3B, PDE5A, GUCY1A2, GUCY1A1, GUCY1B1, KNG1, BDKRB2, OPRD1, ADORA1, ADORA3, GNAI1, GNAI3, GNAI2, INS, INSR, IRS1, IRS2, IRS4, PIK3CG, PIK3R5, PIK3R6, AKT1, AKT2, AKT3, NOS3, ADRB1, ADRB2, ADRB3, PRKCE, KCNJ8, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, BAD, VASP, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3
## 34 LDLR, SCARB1, CD81, CLDN4, CLDN3, CLDN7, CLDN19, CLDN16, CLDN14, CLDN15, CLDN17, CLDN20, CLDN11, CLDN18, CLDN22, CLDN5, CLDN10, CLDN8, CLDN6, CLDN2, CLDN1, CLDN9, CLDN23, CLDN34, CLDN25, CLDN24, OCLN, OAS1, OAS2, OAS3, RNASEL, RIGI, MAVS, TRAF3, TBK1, IKBKE, IRF3, IRF7, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNG, TLR3, TICAM1, TRAF6, RIPK1, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, TNF, CXCL10, EIF2AK1, EIF2AK2, EIF2AK3, EIF2AK4, IFIT1, IFIT1B, EIF3E, EIF2S1, STAT3, SOCS3, IFNAR1, IFNAR2, JAK1, TYK2, STAT1, STAT2, IRF9, MX1, MX2, RSAD2, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2CA, PPP2CB, PIAS1, EGF, EGFR, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, BRAF, RAF1, ARAF, YWHAZ, YWHAB, YWHAQ, YWHAE, YWHAH, YWHAG, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, GSK3B, CTNNB1, BAD, CDKN1A, TP53, CDK2, CDK4, CDK6, RB1, E2F1, E2F2, E2F3, TNFRSF1A, TRADD, TRAF2, FASLG, FAS, FADD, CASP8, CASP3, CFLAR, BID, BAX, BAK1, CYCS, APAF1, CASP9, PSME3, RXRA, PPARA, NR1H3, CCND1, MYC
## 40 HSPG2, SLC10A1, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD3, CDKN1A, MAPK8, MAPK10, MAPK9, MYC, EGR2, EGR3, CREBBP, EP300, FASLG, DDB1, DDB2, MAP3K1, YWHAZ, YWHAB, YWHAQ, MAP2K4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, MMP9, BCL2, BAD, FAS, FADD, CASP8, CASP10, BID, BAX, APAF1, CYCS, CASP9, CASP3, CASP12, BIRC5, TP53, CCNA2, CCNA1, CDK2, CCNE1, CCNE2, RB1, E2F1, E2F2, E2F3, ATP6AP1, PRKCA, PRKCB, PRKCG, NFATC1, NFATC2, NFATC3, NFATC4, TNF, JAK1, JAK2, JAK3, TYK2, STAT3, STAT1, STAT2, STAT4, STAT5A, STAT5B, STAT6, VDAC3, PTK2B, SRC, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, JUN, SMAD4, ATF2, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, ATF4, CREB5, ATF6B, CXCL8, PCNA, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, FOS, ELK1, TLR2, MYD88, TIRAP, TLR4, IRAK4, IRAK1, TRAF6, TAB1, TAB2, MAP3K7, IL6, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAP2K7, TICAM2, TLR3, TICAM1, RIGI, IFIH1, MAVS, TRAF3, IKBKE, TBK1, DDX3X, IRF3, IRF7, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNAR1
## 42 CD46, MSN, SLAMF1, CLEC4M, CD209, RIGI, IFIH1, MAVS, TRAF3, IKBKE, TBK1, IRF3, CHUK, IKBKB, IKBKG, NFKBIB, NFKBIA, NFKB1, RELA, TLR7, TLR9, MYD88, IRAK1, IRAK4, IRF7, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, TLR2, TLR4, TRAF6, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, TNFAIP3, MAP3K7, TAB2, MAPK8, MAPK10, MAPK9, JUN, FOS, IL1A, IL1B, IL6, IL12A, IL12B, IFNAR1, IFNAR2, RACK1, JAK1, TYK2, STAT1, STAT2, IRF9, OAS1, OAS2, OAS3, ADAR, MX1, MX2, EIF2AK1, EIF2AK2, EIF2AK3, EIF2AK4, RAB9A, RAB9B, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, EIF3H, EIF2S1, RCHY1, TP53, TP73, BBC3, FASLG, FAS, TRADD, FADD, CASP8, BID, BAX, BAK1, BCL2, BCL2L1, BAD, CYCS, APAF1, CASP9, CASP3, CDKN1B, CCND1, CCND2, CCND3, CCNE1, CCNE2, CDK4, CDK6, CDK2, CD3D, CD3E, CD3G, CD28, IL2, IL2RA, IL2RB, IL2RG, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, CBLB, AKT1, AKT2, AKT3, GSK3B, JAK3, STAT3, STAT5A, STAT5B, FCGR2B
## 43 CR2, CD19, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, TLR2, MYD88, IRAK4, IRAK1, TRAF6, TAB1, TAB2, MAP3K7, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, TNF, IL6, RIGI, MAVS, TRAF3, TBK1, IKBKE, IRF7, IRF3, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNAR1, IFNAR2, JAK1, TYK2, STAT1, STAT2, IRF9, EIF2AK2, OAS1, OAS2, OAS3, CXCL10, ISG15, FAS, FADD, CASP8, BID, BCL2L11, BCL2, BAX, BAK1, CYCS, APAF1, CASP9, CASP3, CD3E, CD3G, CD3D, CD247, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD1, PSMD3, PSMD12, PSMD11, PSMD6, PSMD7, PSMD13, PSMD4, PSMD14, PSMD8, ADRM1, SEM1, TAP1, TAP2, TAPBP, PDIA3, CALR, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, B2M, SNW1, SIN3A, HDAC1, HDAC2, NCOR2, SAP30, SAP30L, CIR1, RBPJL, RBPJ, HES1, FCER2, RUNX3, MYC, USP7, MDM2, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, DDB2, POLK, TRAF5, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MAP3K14, RELB, NFKB2, TRADD, NFKBIB, NFKBIE, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, TRAF2, RIPK1, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, JUN, ENTPD3, ENTPD8, ENTPD1, CD40, CD44, ITGAL, CD58, ICAM1, VIM, TNFAIP3, JAK3, STAT3, LYN, SYK, NEDD4, RAC1, IGH, BTK, BLNK, PLCG2, SKP2, CDKN1B, CCND1, CCND2, CCND3, CDK4, CDK6, CCNA2, CCNA1, CCNE1, CCNE2, CDK2, RB1, E2F1, E2F2, E2F3
## 53 FHIT, RARB, RXRA, RXRB, RXRG, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, BCL2, CYCS, APAF1, CASP9, CASP3, MYC, MAX, ZBTB17, CDKN2B, CDK4, CDK6, CCND1, CKS1B, CKS2, SKP2, CDKN1B, CDK2, CCNE1, CCNE2, RB1, E2F1, E2F2, E2F3, COL4A2, COL4A4, COL4A6, COL4A1, COL4A5, COL4A3, LAMA1, LAMA2, LAMA3, LAMA5, LAMA4, LAMB1, LAMB2, LAMB3, LAMB4, LAMC1, LAMC2, LAMC3, FN1, ITGA2, ITGA2B, ITGA3, ITGA6, ITGAV, ITGB1, PTK2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, AKT1, AKT2, AKT3, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, BIRC2, BIRC3, XIAP, BIRC7, BCL2L1, TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, PTGS2, NOS2
## 135 TPSD1, TPSAB1, TPSB2, PLG, PRSS3, PRSS2, PRSS1, TMPRSS2, TMPRSS4, TMPRSS11D, PRKCB, OAS1, OAS2, OAS3, RNASEL, DNAJB1, DNAJC3, EIF2AK2, EIF2S1, TRIM25, RIGI, IFIH1, NLRX1, MAVS, CHUK, IKBKB, IKBKG, NFKBIB, NFKBIA, NFKB1, RELA, CALCOCO2, TLR3, TICAM1, TRAF3, TBK1, IKBKE, IRF3, CREBBP, EP300, TLR4, TLR7, MYD88, IRAK4, IRF7, IL1A, IL1B, IL6, IL12A, IL12B, TNF, CXCL8, CCL2, CCL5, CXCL10, ICAM1, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNAR1, IFNAR2, JAK1, TYK2, SOCS3, STAT1, STAT2, IRF9, MX1, MX2, ADAR, PML, IFNG, IFNGR1, IFNGR2, JAK2, CIITA, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, NLRP3, PYCARD, CASP1, IL18, IL33, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, CCND3, CDK4, CDK6, TNFSF10, TNFRSF10A, TNFRSF10B, FASLG, FAS, TNFRSF1A, TRADD, FADD, CASP8, BID, BAX, BAK1, VDAC1, SLC25A4, SLC25A5, SLC25A6, SLC25A31, CYCS, APAF1, CASP9, CASP3, CPSF4, CPSF4L, PABPN1, PABPN1L, BCL2L2-PABPN1, NXF1, NXF2, NXF2B, NXF3, NXT1, NXT2, HNRNPUL1, RAE1, NUP98, RSAD2, FDPS, PRKCA, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, ACTG1, ACTB, RAB11A, RAB11B, XPO1, KPNA1, KPNA2, KPNA7, KPNA6, KPNA5
## 35 TLR4, TICAM1, TLR2, TLR6, TLR9, MYD88, IRAK1, IRAK4, TRAF6, MAP2K4, MAPK8, MAPK10, MAPK9, MAPK1, MAPK3, MAPK11, MAPK12, MAPK13, MAPK14, FOS, JUN, IKBKG, CHUK, IKBKB, NFKBIA, NFKB1, RELA, IFNB1, CCL5, CCL2, TNF, IL12A, IL12B, IL6, CXCL8, CCL3, CCL3L1, CCL3L3, IL1B, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2CA, PPP2CB, IFNG, IFNGR1, IFNGR2, TNFRSF1A, NOS2, C3, CALR, C1QA, C1QB, C1QC, IL10, TGFB1, TGFB2, TGFB3, ACE, KNG1, BDKRB2, GNAQ, GNA11, GNA14, GNA15, PLCB1, PLCB2, PLCB3, PLCB4, GNAI1, GNAI3, GNAI2, GNAO1, GNAS, GNAL, ADCY1, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, TGFBR2, TGFBR1, SMAD2, SERPINE1, FASLG, FAS, FADD, CASP8, CFLAR, CD3D, CD3E, CD3G, CD247, IL2
## 50 IFNG, IFNGR1, IFNGR2, JAK1, JAK2, STAT1, CIITA, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, IRGM, NOS2, SOCS1, MYD88, IRAK1, IRAK4, TRAF6, MAP3K7, TAB1, TAB2, MAPK1, MAPK3, MAPK8, MAPK10, MAPK9, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, CHUK, IKBKB, IKBKG, NFKBIA, NFKBIB, NFKB1, RELA, IL12A, IL12B, TNF, BCL2, BCL2L1, BIRC2, BIRC3, XIAP, BIRC7, LY96, TLR4, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, TLR2, LAMA1, LAMA2, LAMA3, LAMA5, LAMA4, LAMB1, LAMB2, LAMB3, LAMB4, LAMC1, LAMC2, LAMC3, ITGA6, ITGB1, LDLR, TNFRSF1A, CASP8, CASP3, CYCS, CASP9, GNAI1, GNAI3, GNAI2, GNAO1, PIK3CG, PIK3R5, PIK3R6, PDPK1, AKT1, AKT2, AKT3, BAD, CD40LG, CD40, PPIF, CCR5, ALOX5, IL10, IL10RA, IL10RB, TYK2, STAT3, TGFB1, TGFB2, TGFB3
## 70 TLR1, TLR2, TLR6, LBP, CD14, LY96, TLR3, TLR4, TLR5, TLR7, TLR8, CTSK, TLR9, RAC1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, TOLLIP, MYD88, TIRAP, FADD, CASP8, IRAK4, IRAK1, TRAF6, TAB1, TAB2, MAP3K7, IKBKG, CHUK, IKBKB, NFKBIA, NFKB1, RELA, MAP3K8, MAP2K1, MAP2K2, MAPK1, MAPK3, MAP2K3, MAP2K6, MAP2K4, MAP2K7, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, JUN, FOS, TNF, IL1B, IL6, IL12A, IL12B, CXCL8, CCL5, CCL3, CCL3L1, CCL3L3, CCL4, CCL4L2, CCL4L1, TICAM2, TICAM1, RIPK1, IRF5, IRF7, SPP1, IKBKE, TBK1, TRAF3, IRF3, CD40, CD80, CD86, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNAR1, IFNAR2, STAT1, CXCL10, CXCL9, CXCL11
## 83 TNF, TNFRSF1A, TRADD, FADD, CASP8, CASP10, CASP3, BID, BAX, CYCS, CASP9, APAF1, AKT1, AKT2, AKT3, BAD, BCL2, CAMK2A, CAMK2D, CAMK2B, CAMK2G, IFNG, IFNGR1, IFNGR2, JAK1, JAK2, STAT1, CIITA, RFX5, RFXANK, RFXAP, NFYA, NFYB, NFYC, CREB1, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, CD74, CREBBP, EP300, IL10, IL10RA, IL10RB, CTSS, CLEC4E, FCER1G, CLEC7A, SRC, SYK, CARD9, MALT1, BCL10, NOD2, RIPK2, HSPA9, HSPD1, LBP, TLR2, TLR1, TLR6, TLR4, CD14, TIRAP, MYD88, IRAK4, IRAK1, IRAK2, TRAF6, NFKB1, RELA, MAPK11, MAPK12, MAPK13, MAPK14, MAPK1, MAPK3, MAPK8, MAPK10, MAPK9, NOS2, IL6, IL12A, IL12B, IL18, IL23A, IL1A, IL1B, CEBPB, CEBPG, TLR9, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, CLEC4M, CD209, ARHGEF12, RHOA, LSP1, PLK3, KSR1, RAF1, TGFB1, TGFB2, TGFB3, CYP27B1, VDR, CAMP, C3, CR1, CR1L, ITGAX, ITGB2, ITGAM, PLA2R1, MRC1, MRC2, SPHK1, SPHK2, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PIK3C3, RAB5A, RAB5B, RAB5C, EEA1, RAB7A, CTSD, TCIRG1, ATP6V0A2, ATP6V0A4, ATP6V0A1, ATP6V0D1, ATP6V0D2, ATP6V1H, ATP6AP1, ATP6V0C, ATP6V0B, LAMP1, LAMP2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, CORO1A, IGH, FCGR1A, FCGR2A, FCGR2B, FCGR2C, FCGR3A, FCGR3B
## 86 TMPRSS2, ACE2, NRP1, ACE, MAS1, AGTR1, CYBB, NFKB1, RELA, TNF, IL6, IL1B, IL12A, IL12B, MMP3, MMP1, CCL2, CXCL8, ADAM17, TNFRSF1A, NFKBIA, NFKBIB, HBEGF, EGFR, IL6R, IL6ST, JAK1, TYK2, STAT3, IL2, CSF3, CSF2, CXCL10, RPS2, RPS3, RPS3A, RPS4Y1, RPS4X, RPS4Y2, RPS5, RPS6, RPS7, RPS8, RPS9, RPS10, RPS10-NUDT3, RPS11, RPS12, RPS13, RPS14, RPS15, RPS15A, RPS16, RPS17, RPS18, RPS19, RPS20, RPS21, RPS23, RPS24, RPS25, RPS26, RPS27, RPS27L, RPS27A, RPS28, RPS29, FAU, RPSA, RPL3L, RPL3, RPL4, RPL5, RPL6, RPL7, RPL7A, RPL8, RPL9, RPL10L, RPL10, RPL10A, RPL11, RPL12, RPL13, RPL13A, RPL14, RPL15, RPL17, RPL17-C18orf32, RPL18, RPL18A, RPL19, RPL21, RPL22L1, RPL22, RPL23, RPL23A, RSL24D1, RPL24, RPL26, RPL26L1, RPL27, RPL27A, RPL28, RPL29, RPL30, RPL31, RPL32, RPL34, RPL35, RPL35A, RPL36, RPL37, RPL37A, RPL38, RPL39, UBA52, RPL41, RPL36AL, RPL36A, RPL36A-HNRNPH2, RPLP0, RPLP1, RPLP2, IGH, FCGR2A, SYK, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, MAPK1, MAPK3, MAPK11, MAPK12, MAPK13, MAPK14, TLR2, TLR4, MYD88, TLR7, TLR8, IRAK4, IRAK1, TRAF6, MAP3K7, TAB2, MAPK8, MAPK10, MAPK9, FOS, JUN, CHUK, IKBKB, IKBKG, NLRP3, CASP1, TLR3, RIGI, ISG15, IFIH1, MAVS, TRAF3, IKBKE, TBK1, IRF3, CGAS, STING1, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNAR1, IFNAR2, STAT1, STAT2, IRF9, ADAR, OAS1, OAS2, OAS3, MX1, MX2, EIF2AK2, C5AR1, C3AR1, C3, CFB, CFD, C5, C6, C7, C8A, C8B, C8G, C9, SELP, VWF, C1QA, C1QB, C1QC, C1R, C1S, C2, C4A, C4B, MBL2, MASP1, MASP2, F2, F13A1, F13B, FGA, FGB, FGG
## 99 TLR2, TLR4, MYD88, IRAK1, IRAK4, TRAF6, MAP3K7, TAB1, TAB2, NFKBIB, NFKBIA, NFKB1, RELA, IL1A, IL1B, IL12A, IL12B, TNF, IL4, NOS2, IL10, TGFB1, TGFB2, TGFB3, C3, CR1, CR1L, ITGAM, ITGB2, IGH, FCGR1A, FCGR2A, FCGR2C, FCGR3A, FCGR3B, ITGA4, ITGB1, PTGS2, PRKCB, NCF1, NCF2, NCF4, CYBB, CYBA, MAPK1, MAPK3, ELK1, FOS, JUN, MAPK11, MAPK12, MAPK13, MAPK14, IFNG, IFNGR1, IFNGR2, JAK1, JAK2, STAT1, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, MARCKSL1, EEF1A1, EEF1A2, PTPN6
## 112 ITGA5, ITGB1, ITGAM, ITGB2, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, RHOA, CFL1, CFL2, CASP3, CASP7, CASP1, PYCARD, NLRP3, IL1B, C1QA, C1QB, C1QC, C1R, C1S, C2, C4A, C4B, C3, C5, SERPING1, C4BPA, C4BPB, LY96, TLR4, CD14, TIRAP, MYD88, IRAK4, IRAK1, TRAF6, NFKB1, RELA, TICAM2, TICAM1, IRF3, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, MAPK1, MAPK3, FOS, JUN, IL6, IL12A, IL12B, IL23A, TNF, IL10, IRF1, IRF8, SFTPA1, SFTPA2, GNAI1, GNAI3, GNAI2, CXCL8, CXCL5, CXCL6, NOD1, IL1A, NOS2
## 130 CLEC7A, LSP1, HRAS, KRAS, NRAS, MRAS, RRAS, RRAS2, RAF1, RELA, RELB, IL12A, IL12B, IL1B, SYK, PTPN11, MAP3K14, CHUK, NFKB2, PLCG2, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, IL2, IL10, EGR2, EGR3, PTGS2, PRKCD, MAPK1, MAPK3, NLRP3, PYCARD, CASP1, CARD9, BCL10, MALT1, CASP8, IKBKG, IKBKB, NFKBIA, NFKB1, TNF, IL6, IL23A, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, JUN, CBLB, CLEC6A, FCER1G, CLEC4M, CD209, ARHGEF12, RHOA, PAK1, KSR1, PLK3, SRC, IKBKE, STAT1, IRF9, STAT2, IL17D, CYLD, BCL3, CCL17, CCL22, MAPKAPK2, CLEC4E, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MDM2, IRF1, CLEC4D, CLEC1B
## 36 PRKACA, PRKACB, PRKACG, ITGAV, ITGB3, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, STAT1, TP53, ESR1, THRB, NCOR1, SIN3A, HDAC1, HDAC2, HDAC3, THRA, RXRA, RXRB, RXRG, KAT2B, KAT2A, NCOA1, NCOA2, NCOA3, CREBBP, EP300, MED4, MED12L, MED12, MED13L, MED13, MED14, MED16, MED17, MED24, MED27, MED30, MED1, CCND1, GATA4, RCAN1, HIF1A, MYC, MYH7, MYH6, ATP2A1, ATP2A3, ATP2A2, PLN, WNT4, CTNNB1, NOTCH1, NOTCH2, NOTCH3, NOTCH4, BMP4, PLCB1, PLCB2, PLCB3, PLCB4, PLCD1, PLCD3, PLCD4, PLCE1, PLCG1, PLCG2, PLCZ1, PRKCA, PRKCB, PRKCG, SLC9A1, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, SLC16A2, SLC16A10, SRC, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, GSK3B, MDM2, TSC2, RHEB, MTOR, TBC1D4, PFKFB2, BAD, FOXO1, CASP9, RCAN2, SLC2A1, PFKM, PFKP, PFKL, SLCO1C1, DIO1, DIO2, DIO3, ACTG1, ACTB
## 160 FCGR3A, FCGR3B, SYK, MAP3K7, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, SIGLEC9, CYBB, NCF1, CYBA, NCF2, NCF4, RAC1, RAC2, TLR7, TLR8, ELANE, MPO, ACTG1, ACTB, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, PADI4, IGH, FCGR1A, FCGR2A, ITGAM, ITGB2, ITGAL, CLEC7A, SRC, PLCB1, PLCB2, PLCB3, PLCB4, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, ATG7, FPR1, FPR3, FPR2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, NFKB1, RELA, C3, CR1, CR1L, C5, C5AR1, HMGB1, TLR2, TLR4, MAPK11, MAPK12, MAPK13, MAPK14, ITGA2B, ITGB3, FGA, FGB, FGG, GP1BA, VWF, SELP, SELPLG, AGER, CASP4, CASP1, GSDMD, HAT1, H2AX, H2AC20, H2AC12, H2AC1, H2AC25, H2AB3, H2AC8, H2AC4, MACROH2A2, MACROH2A1, H2AC19, H2AJ, H2AB1, H2AC17, H2AC18, H2AC11, H2AC21, H2AZ2, H2AC7, H2AZ1, H2AC15, H2AC6, H2AC13, H2AC14, H2AC16, H2AB2, H2BC15, H2BC9, H2BC14, H2BW1, H2BC1, H2BC18, H2BC17, H2BC3, H2BC8, H2BC13, H2BC4, H2BC5, H2BC6, H2BC10, H2BC21, H2BC11, H2BC12, H2BC26, H2BC7, H2BW2, H2BK1, H2BC12L, H4C16, H4C15, H4C9, H4C4, H4C6, H4C12, H4C11, H4C3, H4C8, H4C2, H4C5, H4C13, H4C14, H4C1, H4C7, H3-5, H3-3B, H3C4, H3C3, H3C1, H3-3A, H3-4, H3C14, H3C15, H3C13, H3C6, H3C11, H3C8, H3C12, H3C10, H3C2, H3C7, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HDAC10, HDAC11, AZU1, CTSG, CAMP, CLCN3, CLCN4, CLCN5, AQP9
## 38 NGF, BDNF, NTF4, NTF3, NTRK1, NTRK2, NTRK3, SH2B2, SH2B1, SH2B3, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, BRAF, MAP2K1, MAP2K2, MAPK1, MAPK3, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, RPS6KA5, ATF4, BCL2, KIDINS220, FRS2, CRK, CRKL, RAPGEF1, RAP1A, RAP1B, MAP3K3, MAP2K5, MAPK7, MAPK11, MAPK12, MAPK13, MAPK14, MAPKAPK2, SHC1, SHC2, SHC3, SHC4, GAB1, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, NFKBIB, NFKBIA, NFKBIE, NFKB1, RELA, FOXO3, FASLG, BAD, GSK3B, PDPK1, IRS1, PLCG1, PLCG2, PRKCD, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, ABL1, PTPN11, MATK, NGFR, ARHGDIB, ARHGDIA, ARHGDIG, RHOA, CDC42, RAC1, MAP3K1, MAP3K5, MAP2K7, MAPK8, MAPK10, MAPK9, JUN, TP53, BAX, TP73, TRAF6, ZNF274, PRDM4, MAGED1, BEX3, YWHAE, RIPK2, IRAK1, IRAK2, IRAK3, IRAK4, IKBKB, SORT1, PSEN1, PSEN2
## 63 GNRH1, GNRH2, GNRHR, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, ATF4, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, PRKCA, PRKCB, PRKCD, CACNA1C, CACNA1D, CACNA1F, CACNA1S, MAP3K1, MAP3K2, MAP3K3, MAP3K4, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAPK7, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PLD1, PLD2, SRC, CDC42, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, JUN, LHB, CGA, FSHB, PTK2B, MMP2, MMP14, HBEGF, EGFR, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, ELK1, EGR1
## 98 KNG1, BDKRB1, BDKRB2, HTR2A, HTR2B, HTR2C, HRH1, P2RY2, GNAQ, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PLA2G6, ALOX12, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PRKCE, PPP1CA, PPP1CB, PPP1CC, TRPA1, TRPV1, ASIC1, ASIC2, ASIC3, ASIC4, ASIC5, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, IL1B, IL1R1, IL1RAP, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, NGF, NTRK1, PLCG1, PLCG2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PRKCD, SRC, TRPM8, PTGER2, PTGER4, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, TRPV4, F2RL1, CYP2J2, PRKCA, PRKCB, PRKCG, PRKCH, PRKCQ, IGF1, TRPV2, TRPV3
## 41 RIGI, IFIH1, MAVS, DHX58, TRAF3, TANK, AZI2, TBKBP1, IKBKG, TBK1, IKBKE, IRF3, IRF7, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNW1, IFNE, IFNK, TRADD, FADD, RIPK1, CASP8, CASP10, CHUK, IKBKB, NFKBIB, NFKBIA, NFKB1, RELA, TRAF2, MAP3K7, TRAF6, MAP3K1, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, CXCL8, TNF, IL12A, IL12B, CXCL10, TRIM25, CYLD, RNF125, ISG15, ATG5, ATG12, NLRX1, STING1, OTUD5, SIKE1, DDX3X, PIN1, TKFC
## 48 NOD1, RIPK2, IKBKG, CHUK, IKBKB, NFKBIB, NFKBIA, NFKB1, RELA, IL1B, IL18, IL6, TNF, CXCL8, CXCL1, CXCL2, CXCL3, CCL2, CCL5, CAMP, DEFA1, DEFA3, DEFA4, DEFA5, DEFA6, DEFA1B, DEFB4A, DEFB4B, DEFB103A, DEFB103B, NOD2, MAP3K7, TAB1, TAB2, TAB3, MAPK1, MAPK3, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, JUN, ATG16L1, ATG5, ATG12, GABARAP, GABARAPL1, GABARAPL2, MAP1LC3C, MAP1LC3B, MAP1LC3A, MAP1LC3B2, SUGT1, SHARPIN, RBCK1, RNF31, XIAP, CARD6, TRIP6, ERBIN, BIRC2, BIRC3, TRAF2, TRAF5, TRAF6, CARD9, TNFAIP3, MAVS, TRAF3, TBK1, IKBKE, TANK, IRF3, IRF7, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, NLRX1, ANTXR2, ANTXR1, NLRP1, PYCARD, CASP1, BCL2, BCL2L1, CTSB, NLRP3, PANX1, P2RX7, TRPM2, TRPM7, TRPV2, CASR, GPRC6A, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, VDAC1, VDAC2, VDAC3, MCU, OAS1, OAS2, OAS3, RNASEL, DHX33, MFN1, MFN2, RIPK1, RIPK3, DNM1L, NAMPT, CYBB, CYBA, TXNIP, TXN, TXN2, NEK7, BRCC3, HSP90AA1, HSP90AB1, CARD8, PYDC1, PYDC2, MEFV, PSTPIP1, CASP8, FADD, CASP12, CARD18, CARD16, NLRP6, NLRP7, NLRP12, NAIP, NLRC4, PRKCD, GBP2, GBP5, AIM2, IFI16, TP53BP1, PYDC5, RHOA, PKN1, PKN2, YWHAE, GBP1, GBP3, GBP4, GBP7, CASP5, CASP4, GSDMD, IFNAR1, IFNAR2, JAK1, TYK2, STAT1, STAT2, IRF9, TLR4, TICAM1, MYD88, IRAK4, STING1
## 54 IL25, IL17RA, IL17RB, TRADD, FADD, CASP3, CASP8, TRAF3IP2, TRAF6, NFKB1, RELA, FOS, FOSB, JUN, JUND, FOSL1, IL4, IL5, IL13, CCL17, CCL11, IL17A, IL17F, IL17RC, TRAF3, ANAPC5, TNFAIP3, HSP90AA1, HSP90AB1, HSP90B1, TBK1, TAB2, TAB3, MAP3K7, IKBKG, CHUK, IKBKB, NFKBIA, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, MAPK1, MAPK3, MAPK4, MAPK6, MAPK7, MAPK15, CEBPB, TRAF4, IKBKE, USP25, TRAF5, TRAF2, SRSF1, ELAVL1, GSK3B, CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, CXCL10, CCL2, CCL7, CCL20, IL6, TNF, PTGS2, CSF3, CSF2, DEFB4A, DEFB4B, MUC5AC, MUC5B, S100A7, S100A7A, S100A8, S100A9, LCN2, MMP1, MMP3, MMP9, MMP13, IL17C, IL17RE, IL1B, IFNG, IL17B, IL17D
## 44 ASPDH, QPRT, NAPRT, PNP, NMRK1, NMRK2, NT5C2, NT5C1A, NT5C1B, NT5C, NT5M, NT5C1B-RDH14, NT5DC4, NT5E, NMNAT3, NMNAT1, NMNAT2, ENPP1, ENPP3, NUDT12, NADSYN1, NAMPT, CD38, BST1, SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7, NADK, NADK2, NNT, NNMT, AOX1
## 51 SPTLC1, SPTLC2, SPTLC3, CERS1, CERS2, CERS4, CERS3, CERS6, CERS5, DEGS1, DEGS2, SMPD1, SGMS1, SGMS2, TNF, TNFRSF1A, NSMAF, SMPD2, ASAH1, ASAH2, ACER2, ACER1, TRADD, TRAF2, CTSD, BID, BAX, MAP3K5, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, PRKCZ, AKT1, AKT2, AKT3, BCL2, PPP2CA, PPP2CB, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3B, PPP2R3C, PPP2R3A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PPP2R5A, TP53, FCER1A, MS4A2, FCER1G, FYN, GAB2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PLD1, PLD2, SPHK1, SPHK2, KNG1, ADORA1, ADORA3, BDKRB2, OPRD1, GNAI1, GNAI3, GNAI2, PLCB1, PLCB2, PLCB3, PLCB4, PRKCE, MAPK1, MAPK3, SGPP1, SGPP2, ABCC1, SGPL1, S1PR1, S1PR2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, PDPK1, NOS3, RAC1, RAC2, RAC3, S1PR3, GNAQ, PRKCA, PRKCB, PRKCG, S1PR4, S1PR5, GNA12, GNA13, RHOA, ROCK1, ROCK2, PTEN, NFKB1, RELA
## 59 ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, ADCY10, PRKACA, PRKACB, PRKACG, LIPE, APLN, APELA, APLNR, GNAI1, GNAI3, GNAI2, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, RYR1, RYR2, RYR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, NOS1, NOS2, NOS3, PRKCE, SLC9A1, SLC8A1, SLC8A2, SLC8A3, MYLK, MYLK2, MYLK3, MYLK4, MYL2, MYL3, MYL4, HRAS, KRAS, NRAS, RRAS, RRAS2, MRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, RPS6KB1, RPS6KB2, RPS6, PIK3CG, PIK3R5, PIK3R6, AKT1, AKT2, AKT3, MTOR, EGR1, SPP1, JAG1, NOTCH3, CCND1, PDE3B, PIK3C3, PIK3R4, BECN1, BECN2, MAP1LC3C, MAP1LC3B, MAP1LC3A, MAP1LC3B2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, PLIN1, PPARGC1A, UCP1, NRF1, TFAM, KLF2, SPHK1, SPHK2, GNA13, CAMK4, HDAC4, HDAC5, MEF2A, BORCS8-MEF2B, MEF2B, MEF2C, MEF2D, TGFBR1, SMAD2, SMAD3, SMAD4, ACTA2, CDH1, CCN2, AGTR1, SERPINE1, PLAT
## 127 OXT, OXTR, GNAQ, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PTGS2, MAP2K5, MAPK7, JUN, FOS, MEF2C, CCND1, ELK1, RYR1, RYR2, RYR3, CD38, TRPM2, KCNJ2, KCNJ12, KCNJ18, KCNJ4, KCNJ14, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, EEF2K, EEF2, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNB1, CACNB2, CACNB3, CACNB4, CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, CACNG1, CACNG2, CACNG3, CACNG4, CACNG5, CACNG6, CACNG7, CACNG8, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, RGS2, RCAN1, CAMKK2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, CAMK1D, CAMK1G, CAMK1, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, NOS3, GUCY1A2, GUCY1A1, GUCY1B1, NPPA, NPR1, NPR2, MYLK, MYLK2, MYLK3, MYLK4, MYL6B, MYL6, MYL9, ACTG1, ACTB, RHOA, ROCK1, ROCK2, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, PPP1R12B, PPP1R12C, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, GNAI1, GNAI3, GNAI2, GNAO1, PIK3CG, PIK3R5, PIK3R6, SRC, KCNJ3, KCNJ6, KCNJ9, KCNJ5, EGFR, CDKN1A
## 62 GSTP1, CDKN1B, CDK2, CCNE1, CCNE2, RB1, E2F1, E2F2, E2F3, TMPRSS2, ERG, PLAU, PLAT, MMP3, MMP9, ZEB1, IL1R2, SPINT1, ETV5, INS, PDGFA, PDGFB, PDGFC, PDGFD, EGF, TGFA, IGF1, INSRR, PDGFRA, PDGFRB, FGFR1, FGFR2, EGFR, ERBB2, IGF1R, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, PDPK1, NKX3-1, AKT1, AKT2, AKT3, CASP9, BAD, FOXO1, CDKN1A, MDM2, TP53, GSK3B, CREB1, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, CTNNB1, CREBBP, EP300, TCF7, TCF7L1, TCF7L2, LEF1, CCND1, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, BCL2, MTOR, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, SRD5A2, AR, HSP90AA1, HSP90AB1, HSP90B1, KLK3
## 75 IGH, FCER1A, MS4A2, FCER1G, SYK, LYN, BTK, INPP5D, PLCG1, PLCG2, PRKCA, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, RAC1, RAC2, RAC3, MAP2K4, MAP2K7, MAP2K3, MAP2K6, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, IL4, IL13, IL3, IL5, CSF2, TNF, LCP2, VAV3, VAV1, VAV2, FYN, GAB2, LAT, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, ALOX5, ALOX5AP
## 79 KRAS, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, ARHGEF6, RAC1, RAC2, RAC3, NFKB1, RELA, AKT1, AKT2, AKT3, CHUK, IKBKB, IKBKG, BAD, BCL2L1, CASP9, ARAF, BRAF, RAF1, MAP2K1, MAPK1, MAPK3, MAPK8, MAPK10, MAPK9, RALGDS, RALA, RALB, RALBP1, CDC42, PLD1, PLD2, TGFA, EGF, EGFR, ERBB2, MTOR, RPS6KB1, RPS6KB2, JAK1, STAT3, STAT1, VEGFA, CDKN2A, CDK4, CDK6, CCND1, RB1, E2F1, E2F2, E2F3, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, BRCA2, RAD51
## 81 PRL, PRLR, JAK2, SHC1, SHC2, SHC3, SHC4, SRC, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, FOXO3, GALT, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, FOS, MAPK8, MAPK10, MAPK9, MAPK11, MAPK12, MAPK13, MAPK14, CCND1, GSK3B, CISH, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS7, SOCS6, STAT1, STAT3, STAT5A, STAT5B, TNFSF11, TNFRSF11A, NFKB1, RELA, ELF5, CSN2, CGA, LHB, LHCGR, CYP17A1, ESR1, ESR2, IRF1, TH, SLC2A2, GCK, CCND2, INS
## 89 FHIT, RARB, RXRA, RXRB, RXRG, CDKN2A, CDK4, CDK6, CCND1, RB1, E2F1, E2F2, E2F3, KRAS, RASSF1, RASSF5, STK4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, BAD, CASP9, FOXO3, EGF, TGFA, EGFR, ERBB2, HGF, MET, GRB2, SOS1, SOS2, HRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, KIF5A, KIF5B, KIF5C, RET, EML4, ALK, JAK3, STAT3, STAT5A, STAT5B
## 100 EGF, TGFA, AREG, EGFR, ERBB2, PLCG1, PLCG2, CAMK2A, CAMK2D, CAMK2B, CAMK2G, PRKCA, PRKCB, PRKCG, CBL, CBLB, STAT5A, STAT5B, SRC, PTK2, CRK, CRKL, ABL1, ABL2, NCK1, NCK2, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, JUN, ELK1, BTC, HBEGF, EREG, ERBB3, NRG1, NRG2, ERBB4, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, MYC, GAB1, NRG3, NRG4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, EIF4EBP1, BAD, GSK3B, CDKN1B, CDKN1A
## 102 VEGFA, KDR, SH2D2A, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, SPHK1, SPHK2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC2, PTGS2, PTK2, SHC2, PXN, CDC42, MAPK11, MAPK12, MAPK13, MAPK14, MAPKAPK2, MAPKAPK3, HSPB1, SRC, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, RAC1, RAC2, RAC3, AKT1, AKT2, AKT3, NOS3, CASP9, BAD
## 106 KIT, FLT3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, CHUK, IKBKB, IKBKG, NFKB1, RELA, BAD, MTOR, EIF4EBP1, RPS6KB1, RPS6KB2, GRB2, SOS1, SOS2, HRAS, NRAS, KRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, STAT3, STAT5A, STAT5B, PIM1, PIM2, RUNX1, CSF1R, MPO, CSF2, IL3, RUNX1T1, PML, RARA, ZBTB16, CEBPA, PER2, SPI1, CD14, ITGAM, FCGR1A, CEBPE, BCL2A1, CCNA2, CCNA1, MYC, DUSP6, JUP, TCF7, TCF7L1, TCF7L2, LEF1, CCND1, PPARD
## 108 FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, HGF, IGF1, PDGFA, PDGFB, PDGFC, PDGFD, EGF, FGFR1, MET, IGF1R, PDGFRA, PDGFRB, EGFR, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, CCND1, CDK4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BAD, PTEN, CDKN2A, MDM2, TP53, CDKN1A, CDK6, RB1, E2F1, E2F2, E2F3, CDH1, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, MITF
## 113 BCR, ABL1, CRK, CRKL, CBL, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BAD, BCL2L1, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, MDM2, TP53, CDKN1B, GRB2, GAB2, PTPN11, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, ARAF, BRAF, MAP2K1, MAP2K2, MAPK1, MAPK3, SHC1, SHC2, SHC3, SHC4, MYC, STAT5A, STAT5B, CDKN2A, CDKN1A, CCND1, CDK4, CDK6, RB1, E2F1, E2F2, E2F3, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD3, SMAD4, MECOM, RUNX1, CTBP1, CTBP2, HDAC1, HDAC2
## 115 EGF, TGFA, EGFR, PDGFA, PDGFB, PDGFRA, PDGFRB, IGF1, IGF1R, PLCG1, PLCG2, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK1D, CAMK1G, CAMK1, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, PRKCA, PRKCB, PRKCG, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, PTEN, CDKN2A, MDM2, TP53, CDKN1A, CCND1, CDK4, CDK6, RB1, E2F1, E2F2, E2F3, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK
## 119 GSK3B, AXIN1, AXIN2, CTNNB1, APC, APC2, TCF7, TCF7L1, TCF7L2, LEF1, BIRC5, MYC, CCND1, KRAS, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BAD, CASP9, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, JUN, FOS, RALGDS, RALA, RALB, RAC1, RAC2, RAC3, RHOA, MAPK8, MAPK10, MAPK9, DCC, CASP3, APPL1, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, MLH1, MSH2, MSH3, MSH6, BAX, PMAIP1, BCL2L11, BBC3, BCL2, CYCS, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAK1, DDB2, POLK, EGF, TGFA, EREG, AREG, EGFR, GRB2, SOS1, SOS2, HRAS, NRAS, MTOR, RPS6KB1, RPS6KB2
## 128 EGF, PDGFA, PDGFB, PDGFC, PDGFD, EGFR, PDGFRA, PDGFRB, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, RALGDS, MAPK8, MAPK10, MAPK9, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, TSC1, TSC2, RHEB, MTOR, RPS6KB1, RPS6KB2, EIF4EBP1, PIP5K1C, PIP5K1A, PIP5K1B, WAS, RAC1, RAC2, RAC3, WASF1, WASF2, WASF3, SP1, PLD1, PLD2, SLC5A7, SLC44A1, SLC44A4, SLC44A5, SLC44A2, SLC44A3, SLC22A1, SLC22A2, SLC22A3, SLC22A5, SLC22A4, CHKA, CHKB, HIF1A, JUN, FOS, PCYT1B, PCYT1A, CHPT1, PLCG1, PLPP1, PLPP3, PLPP2, DGKZ, DGKD, DGKI, DGKA, DGKE, DGKB, DGKH, DGKG, DGKQ, DGKK, PRKCA, PRKCB, PRKCG, LYPLA1, GPCPD1
## 131 EGF, EGFR, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, PDPK1, ILK, AKT1, AKT2, AKT3, CASP9, BAD, FOXO3, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, ELK1, MLH1, CDH1, CTNNB1, CTNNA3, CTNNA1, CTNNA2, AXIN1, AXIN2, APC, APC2, GSK3B, TCF7, TCF7L1, TCF7L2, LEF1, MYC, CCND1, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, ERBB2
## 134 IGH, CD79A, CD79B, LYN, SYK, BTK, DAPP1, BLNK, VAV3, VAV1, VAV2, RAC1, RAC2, RAC3, PLCG2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, GRB2, SOS1, SOS2, RASGRP3, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, FOS, JUN, PRKCB, CARD11, BCL10, MALT1, CHUK, IKBKB, IKBKG, NFKB1, RELA, NFKBIA, NFKBIB, NFKBIE, IFITM1, CD81, CD19, CR2, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, GSK3B, FCGR2B, INPP5D, INPPL1, LILRB2, LILRB1, LILRB5, LILRB4, LILRA1, LILRB3, LILRA3, LILRA2, LILRA4, LILRA6, LILRA5, CD22, CD72, PTPN6, PIK3AP1
## 140 HIF1A, EPAS1, EGLN1, EGLN3, EGLN2, VHL, ELOC, ELOB, RBX1, CUL2, ARNT, ARNT2, CREBBP, EP300, SLC2A1, VEGFA, TGFB1, TGFB2, TGFB3, PDGFB, TGFA, HGF, MET, GAB1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BAD, CRK, CRKL, RAPGEF1, RAP1A, RAP1B, PTPN11, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, ETS1, JUN, RAC1, CDC42, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, PRCC, TFE3, CDKN1A, FH, FLCN
## 146 IGH, FCGR1A, FCGR2A, FCGR3A, FCGR3B, PTPRC, HCK, LYN, SYK, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, RPS6KB1, RPS6KB2, PLCG1, PLCG2, PRKCD, PRKCE, RAF1, MAP2K1, MAPK1, MAPK3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PLA2G6, MARCKS, MARCKSL1, PLD1, PLD2, PLPP1, PLPP3, PLPP2, SPHK1, SPHK2, PRKCA, PRKCB, PRKCG, NCF1, GSN, SCIN, VAV3, VAV1, VAV2, CDC42, WAS, VASP, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, RAC1, RAC2, WASF1, WASF2, WASF3, PAK1, LIMK1, LIMK2, CFL1, CFL2, PIP5K1C, PIP5K1A, PIP5K1B, ARF6, CRK, CRKL, DOCK1, ASAP1, ASAP3, ASAP2, FCGR2B, INPP5D, INPPL1, GAB2, LAT, DNM2, AMPH, BIN1, MYO10
## 166 HLA-A, HLA-B, HLA-C, HLA-G, HLA-E, KIR3DL2, KIR3DL1, KIR3DL3, KIR2DL2, KIR2DL1, KIR2DL3, KIR2DL5A, KLRC1, KLRD1, PTPN6, PTPN11, ICAM1, ICAM2, ITGAL, ITGB2, PTK2B, VAV3, VAV1, VAV2, RAC1, RAC2, RAC3, PAK1, MAP2K1, MAP2K2, MAPK1, MAPK3, TNF, CSF2, IFNG, KIR2DS1, KIR2DS3, KIR2DS4, KIR2DS5, KIR2DS2, KLRC2, KLRC3, NCR2, TYROBP, LCK, IGH, FCGR3A, FCGR3B, NCR1, NCR3, FCER1G, CD247, ZAP70, SYK, LCP2, LAT, PLCG1, PLCG2, SH3BP2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, FYN, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MICB, MICA, ULBP1, ULBP2, ULBP3, KLRK1, KLRC4-KLRK1, HCST, CD48, CD244, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, PRKCA, PRKCB, PRKCG, SH2D1B, SH2D1A, IFNGR1, IFNGR2, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNAR1, IFNAR2, TNFSF10, TNFRSF10A, TNFRSF10B, FASLG, FAS, GZMB, PRF1, CASP3, BID, RAET1G, RAET1L, RAET1E
## 66 CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, PPBP, CXCL8, CXCL9, CXCL10, CXCL11, CXCL12, CXCL13, CXCL16, PF4, PF4V1, CXCL14, XCL1, XCL2, CX3CL1, CCL1, CCL2, CCL3, CCL3L1, CCL3L3, CCL4, CCL4L2, CCL4L1, CCL5, CCL7, CCL8, CCL11, CCL13, CCL14, CCL15, CCL23, CCL16, CCL17, CCL18, CCL19, CCL20, CCL21, CCL22, CCL24, CCL25, CCL26, CCL27, CCL28, CXCR2, CXCR1, CXCR3, CXCR4, CXCR5, CXCR6, XCR1, CX3CR1, CCR8, CCR6, CCR9, CCR4, CCR7, CCR2, CCR5, CCR1, CCR3, CCR10, JAK2, JAK3, STAT1, STAT2, STAT3, STAT5B, GNAI1, GNAI3, GNAI2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, LYN, HCK, FGR, SRC, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, BRAF, MAP2K1, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PIK3CG, PIK3R5, PIK3R6, PRKCZ, AKT1, AKT2, AKT3, FOXO3, CHUK, IKBKB, IKBKG, NFKBIA, NFKBIB, NFKB1, RELA, BAD, GSK3A, GSK3B, ITK, VAV3, VAV1, VAV2, RAC1, RAC2, RAC3, PAK1, CDC42, WAS, RHOA, ROCK1, ROCK2, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, PREX1, ELMO1, DOCK2, PTK2, PXN, BCAR1, CRK, CRKL, PTK2B, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PLCG1, PLCG2, RASGRP2, RAP1A, RAP1B, PARD3, TIAM1, PRKCB, PRKCD, NCF1, GRK7, GRK1, GRK2, GRK3, GRK4, GRK5, GRK6, ARRB1, ARRB2
## 67 TGFB2, TGFB3, TGFB1, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, CDKN1B, FN1, COL1A1, COL1A2, COL3A1, COL4A2, COL4A4, COL4A6, COL4A1, COL4A5, COL4A3, AGT, AGTR1, AGER, NOX1, CYBB, NOX4, PLCD1, PLCD3, PLCD4, PLCB1, PLCB2, PLCB3, PLCB4, PLCG1, PLCG2, PLCE1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCZ, MAPK1, MAPK3, JUN, VEGFA, VEGFB, VEGFC, VEGFD, CCL2, SERPINE1, SELE, VCAM1, ICAM1, MMP2, IL1A, IL1B, IL6, CXCL8, TNF, F3, EDN1, THBD, MAPK11, MAPK12, MAPK13, MAPK14, RELA, NFKB1, MAPK8, MAPK10, MAPK9, DIAPH1, RAC1, CDC42, HRAS, KRAS, NRAS, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, NOS3, FOXO1, BCL2, BAX, CASP3, JAK2, STAT3, PIM1, NFATC1, STAT1, STAT5A, STAT5B, CCND1, CDK4, EGR1
## 69 LPAR1, LPAR2, LPAR4, LPAR5, CXCL12, CXCR4, F2, F2R, INS, EGF, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, PDGFA, PDGFB, PDGFC, PDGFD, INSRR, EGFR, FGFR1, FGFR2, FGFR3, FGFR4, PDGFRA, PDGFRB, FN1, ITGA1, ITGA2, ITGA2B, ITGA3, ITGA4, ITGA5, ITGA6, ITGA7, ITGA8, ITGA9, ITGA10, ITGA11, ITGAV, ITGAL, ITGAM, ITGAX, ITGAD, ITGAE, ITGB1, ITGB2, ITGB3, ITGB4, ITGB5, ITGB6, ITGB7, ITGB8, KNG1, BDKRB1, BDKRB2, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, C5, C6, C7, C8A, C8B, C8G, C9, GNA12, GNA13, GNG12, FGD1, FGD3, PTK2, BCAR1, CRK, CRKL, DOCK1, SRC, SOS1, SOS2, HRAS, KRAS, NRAS, RRAS, RRAS2, MRAS, ARHGEF6, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, VAV3, VAV1, VAV2, TIAM1, ARAF, BRAF, RAF1, MOS, MAP2K1, MAP2K2, MAPK1, MAPK3, AKT1, AKT2, AKT3, RGCC, ARHGEF1, ARHGEF12, ARHGAP35, RHOA, RAC1, RAC2, RAC3, CDC42, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, ARHGEF7, GIT1, ROCK1, ROCK2, MYLK, MYLK2, MYLK3, MYLK4, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, PPP1R12B, PPP1R12C, MYL2, MYL5, MYL7, MYL9, MYL10, MYL12B, MYL12A, MYL11, MYH9, MYH10, MYH11, MYH14, DIAPH1, DIAPH2, SLC9A1, PIP5K1C, PIP5K1A, PIP5K1B, PIP4K2C, PIP4K2A, PIP4K2B, PIKFYVE, LIMK1, LIMK2, DIAPH3, BAIAP2, ENAH, WASL, WASF2, CYFIP1, CYFIP2, NCKAP1, NCKAP1L, ABI2, BRK1, WASF1, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, ACTG1, ACTB, PFN3, PFN1, PFN2, PFN4, PXN, EZR, RDX, MSN, TMSB4X, TMSB4Y, CFL1, CFL2, SSH1, SSH3, SSH2, VCL, IQGAP1, IQGAP2, IQGAP3, GSN, SCIN, ACTN1, ACTN4, APC, APC2, ARHGEF4, SPATA13
## 155 COL1A1, COL1A2, COL2A1, COL4A2, COL4A4, COL4A6, COL4A1, COL4A5, COL4A3, COL6A1, COL6A2, COL6A3, COL6A6, COL6A5, COL9A1, COL9A2, COL9A3, LAMA1, LAMA2, LAMA3, LAMA5, LAMA4, LAMB1, LAMB2, LAMB3, LAMB4, LAMC1, LAMC2, LAMC3, CHAD, RELN, THBS1, COMP, THBS2, THBS3, THBS4, FN1, SPP1, VTN, TNC, TNN, TNR, TNXB, VWF, IBSP, ITGA1, ITGA2, ITGA2B, ITGA3, ITGA4, ITGA5, ITGA6, ITGA7, ITGA8, ITGA9, ITGA10, ITGA11, ITGAV, ITGB1, ITGB3, ITGB4, ITGB5, ITGB6, ITGB7, ITGB8, PDGFA, PDGFB, PDGFC, PDGFD, EGF, IGF1, VEGFA, VEGFB, PGF, VEGFC, VEGFD, HGF, PDGFRA, PDGFRB, IGF1R, KDR, EGFR, FLT1, FLT4, MET, ERBB2, SRC, ARHGAP35, ARHGAP5, RHOA, DIAPH1, ROCK1, ROCK2, MYL2, MYL5, MYL7, MYL9, MYL10, MYL12B, MYL12A, MYL11, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, PPP1R12B, PPP1R12C, MYLK, MYLK2, MYLK3, MYLK4, PIP5K1C, PIP5K1A, PIP5K1B, ACTG1, ACTB, RASGRF1, CAPN2, ACTN1, ACTN4, TLN1, TLN2, FLNA, FLNC, FLNB, PXN, ILK, ZYX, VASP, VCL, PARVB, PARVA, PARVG, PDPK1, AKT1, AKT2, AKT3, GSK3B, CTNNB1, PRKCA, PRKCB, PRKCG, PTK2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, VAV3, VAV1, VAV2, RAC1, RAC2, RAC3, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, CDC42, BCAR1, CRK, CRKL, DOCK1, RAPGEF1, RAP1A, RAP1B, MAPK8, MAPK10, MAPK9, JUN, BRAF, CAV1, CAV2, CAV3, FYN, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, RAF1, MAP2K1, MAPK1, MAPK3, ELK1, CCND1, CCND2, CCND3, BIRC2, BIRC3, XIAP, BAD, BCL2
## 72 CD44, SRC, CTTN, HCLS1, ERBB2, GRB2, VAV3, VAV1, VAV2, HRAS, KRAS, NRAS, RRAS, RRAS2, MRAS, BRAF, RAF1, ARAF, MAP2K1, MAP2K2, MAPK1, MAPK3, RAC1, IQGAP1, CDC42, ELK1, ESR1, CCND1, ACTG1, ACTB, FLNA, FLNC, FLNB, PAK1, TIAM1, ARHGEF1, RHOA, ROCK1, ROCK2, ANK1, ANK2, ANK3, GAB1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, SLC9A1, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, PPP1R12B, PPP1R12C, ARHGEF12, PLCE1, ITPR1, ITPR2, ITPR3, CAMK2A, CAMK2D, CAMK2B, CAMK2G, NANOG, NANOGP8, DDX5, DROSHA, STAT3, MIR21, TWIST1, TWIST2, MIR10A, MIR10B, HOXD10, DCN, IGF1, IGF1R, MTOR, PDPK1, RPS6KB1, RPS6KB2, EIF4B, RPS6, EGFR, CAV1, CAV2, CAV3, CD63, CDKN1A, CASP3, TGFB1, TLR2, TLR4, PDCD4, TNF, IL12B, ERBB3, ERBB4, MYC, CTNNB1, HIF1A, TFAP4, VEGFA, KDR, MET, CBL, TIMP3, THBS1, MMP2, MMP9, LUM, FASLG, FAS, MDM2, TP53, TGFB2, SMAD2, HPSE, HPSE2, SDC1, PLAU, PLAUR, COL1A1, COL1A2, ITGA2, ITGB1, VTN, ITGAV, ITGB3, FN1, ITGB5, HGF, WNT1, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, ITGA5, SDC2, EZR, RDX, MSN, SDC4, FGF2, FGFR1, FRS2, PTPN11, SOS1, SOS2, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, NUDT16L1, PXN, PTK2, HBEGF, GPC1, IGF2, GPC3, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, SHH, IHH, PTCH1, SMO, HSPG2, CTSL, PRKACA, PRKACB, PRKACG, MAPK11, MAPK12, MAPK13, MAPK14, HSPB2, PTPN6
## 91 POMC, ASIP, MC1R, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREBBP, EP300, MITF, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, GNAO1, GNAQ, DVL3, DVL2, DVL1, GSK3B, CTNNB1, TCF7, TCF7L1, TCF7L2, LEF1, KITLG, KIT, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, TYR, TYRP1, DCT, EDN1, EDNRB, GNAI1, GNAI3, GNAI2, PLCB1, PLCB2, PLCB3, PLCB4, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, PRKCA, PRKCB, PRKCG
## 107 LIF, LIFR, IL6ST, JAK1, JAK2, JAK3, STAT3, KLF4, SOX2, MYC, GRB2, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, TBX3, NANOG, NANOGP8, INHBA, INHBB, INHBC, INHBE, NODAL, ACVR1B, ACVR1C, ACVR2A, ACVR2B, SMAD2, SMAD3, BMP4, BMPR1A, BMPR1B, ACVR1, BMPR2, SMAD1, SMAD5, SMAD9, SMAD4, ID1, ID2, ID3, ID4, DUSP9, MAPK11, MAPK12, MAPK13, MAPK14, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, DVL3, DVL2, DVL1, GSK3B, AXIN1, AXIN2, APC, APC2, CTNNB1, TCF3, ESRRB, TCF7, POU5F1, POU5F1B, FGF2, FGFR1, FGFR2, FGFR3, FGFR4, HRAS, KRAS, NRAS, RAF1, IGF1, IGF1R, HESX1, ZIC3, LEFTY1, LEFTY2, SKIL, SMARCAD1, KAT6A, SETDB1, JARID2, REST, RIF1, PCGF1, PCGF2, PCGF3, BMI1, COMMD3-BMI1, PCGF5, PCGF6, PAX6, MEIS1, HOXB1, HOXA1, HOXD1, LHX5, OTX1, NEUROG1, HAND1, DLX5, MYF5, ONECUT1, ISL1, ZFHX3, ESX1
## 109 ESR1, ESR2, NCOA1, NCOA3, FOS, JUN, SP1, CCND1, MYC, PGR, WNT1, WNT4, TNFSF11, ERBB2, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, FGFR1, IGF1, IGF1R, EGF, EGFR, KIT, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, JAG1, JAG2, DLL3, DLL1, DLL4, NOTCH1, NOTCH2, NOTCH3, NOTCH4, HES1, HES5, HEYL, HEY1, HEY2, FLT4, CDKN1A, NFKB2, WNT2, WNT2B, WNT3, WNT3A, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, LRP5, LRP6, DVL3, DVL2, DVL1, FRAT1, FRAT2, GSK3B, AXIN1, AXIN2, APC, APC2, CTNNB1, CSNK1A1L, CSNK1A1, TCF7, TCF7L1, TCF7L2, LEF1, TP53, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, CDK4, CDK6, RB1, E2F1, E2F2, E2F3, BRCA1, BRCA2
## 110 CDX2, MUC2, CDH17, REG4, ABCB1, SHH, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, RARB, RXRA, RXRB, RXRG, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, LRP5, LRP6, DVL3, DVL2, DVL1, FRAT1, FRAT2, GSK3B, AXIN1, AXIN2, APC, APC2, CTNNB1, CSNK1A1L, CSNK1A1, TCF7, TCF7L1, TCF7L2, LEF1, MYC, CCND1, TERT, TERC, EGF, EGFR, ERBB2, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, BCL2, MLH1, CDKN1B, CDK2, CCNE1, CCNE2, RB1, E2F1, E2F2, E2F3, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, CDKN2B, CDH1, CTNNA3, CTNNA1, CTNNA2, JUP, HGF, MET, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, FGFR2, GAB1
## 120 CRH, CRHR1, CRHR2, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, MEN1, ASH2L, RBBP5, WDR5, WDR5B, KMT2A, KMT2D, CDKN2C, CDKN2B, CDKN2A, CDK4, CDK6, CCND1, RB1, E2F1, E2F2, E2F3, RASD1, GNAI1, GNAI3, GNAI2, AHR, AIPL1, AIP, ARNT, CDKN1B, CDK2, CCNE1, CCNE2, CDKN1A, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CAMK2A, CAMK2D, CAMK2B, CAMK2G, RAP1A, RAP1B, BRAF, MAP2K1, MAP2K2, MAPK1, MAPK3, NR4A1, EGFR, USP8, POMC, MC2R, MRAP, PDE8B, PDE8A, PDE11A, NR5A1, SP1, PBX1, CYP11B1, CYP17A1, STAR, NCEH1, ARMC5, AGT, AGTR1, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, KCNK2, CACNA1G, CACNA1H, CACNA1I, ORAI1, KCNA4, KCNK3, LDLR, SCARB1, CYP11A1, HSD3B1, HSD3B2, CYP21A2, FH, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, DVL3, DVL2, DVL1, GSK3B, AXIN1, AXIN2, CTNNB1, APC, APC2, TCF7, TCF7L1, TCF7L2, LEF1
## 150 SLC7A5, SLC3A2, SLC38A9, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C2, ATP6V1C1, ATP6V1D, ATP6V1E2, ATP6V1E1, ATP6V1F, ATP6V1G1, ATP6V1G3, ATP6V1G2, ATP6V1H, LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, LAMTOR5, FLCN, FNIP1, FNIP2, RRAGA, RRAGB, RRAGC, RRAGD, SESN2, CASTOR1, CASTOR2, MIOS, SEH1L, WDR24, WDR59, SEC13, DEPDC5, NPRL2, NPRL3, SKP2, RNF152, RPTOR, AKT1S1, MTOR, DEPTOR, MLST8, TELO2, TTI1, CLIP1, GRB10, LPIN1, LPIN3, LPIN2, ULK1, ULK2, EIF4EBP1, EIF4E, EIF4E2, EIF4E1B, RPS6KB1, RPS6KB2, EIF4B, RPS6, STRADA, STRADB, STK11, CAB39, CAB39L, PRKAA1, PRKAA2, TSC1, TSC2, TBC1D7, RHEB, DDIT4, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, LRP5, LRP6, DVL3, DVL2, DVL1, GSK3B, TNF, TNFRSF1A, IKBKB, INS, IGF1, INSR, IGF1R, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, IRS1, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, PTEN, PDPK1, AKT1, AKT2, AKT3, CHUK, MAPKAP1, RICTOR, PRR5, PRR5L, RHOA, PRKCA, PRKCB, PRKCG, SGK1
## 154 TGFA, EGFR, IGF2, IGF1R, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, ELK1, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PTEN, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, BAD, BCL2L1, MYC, RB1, E2F1, E2F2, E2F3, TERT, TERC, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, CDKN2A, CDK4, CDK6, CCND1, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, LRP5, LRP6, DVL3, DVL2, DVL1, FRAT1, FRAT2, GSK3B, AXIN1, AXIN2, APC, APC2, CTNNB1, CSNK1A1L, CSNK1A1, TCF7, TCF7L1, TCF7L2, LEF1, KEAP1, NFE2L2, HMOX1, NQO1, GSTA5, GSTA2, GSTA4, GSTO2, GSTM4, GSTT2, GSTT1, GSTM3, MGST1, MGST3, GSTM1, GSTM5, MGST2, GSTA1, GSTM2, GSTA3, GSTO1, GSTT2B, GSTP1, TXNRD1, TXNRD3, TXNRD2, HGF, MET, GAB1, ACTG1, ACTB, ACTL6A, ACTL6B, SMARCD1, SMARCD2, SMARCD3, PHF10, DPF1, DPF3, ARID1B, ARID1A, SMARCE1, SMARCB1, SMARCC1, SMARCC2, SMARCA2, SMARCA4, ARID2, PBRM1, BRD7
## 77 INS, IGF1R, IRS1, IRS2, IRS4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, AKT1, AKT2, AKT3, PTEN, HRAS, KRAS, NRAS, MRAS, RRAS, RRAS2, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, HIF1A, DDIT4, TSC2, TSC1, BNIP3, RHEB, RPTOR, DEPTOR, MTOR, AKT1S1, MLST8, RPS6KB1, RPS6KB2, IGBP1, PPP2CA, PPP2CB, ULK1, ULK2, ATG13, ATG101, RB1CC1, ATG2A, ATG2B, WIPI2, WIPI1, ATG9B, ATG9A, SUPT20H, SMCR8, WDR41, C9orf72, RAB8A, RAB39B, SQSTM1, TBK1, TANK, RAB1A, RRAGA, RRAGB, RRAGC, RRAGD, STK11, PRKAA1, PRKAA2, PRKACA, PRKACB, PRKACG, PRKCD, MAPK8, MAPK10, MAPK9, BCL2, BCL2L1, BAD, BECN1, BECN2, NRBF2, PIK3R4, PIK3C3, ATG14, AMBRA1, TRAF6, TP53INP2, VMP1, STX17, UVRAG, SH3GLB1, RUBCN, CAMKK2, MAP3K7, ERN1, ITPR1, DAPK1, DAPK3, DAPK2, HMGB1, PRAP1, EIF2AK3, EIF2AK4, EIF2S1, MTMR3, MTMR4, MTMR14, ZFYVE1, ATG12, ATG5, ATG16L1, ATG16L2, ATG7, ATG10, ATG3, CFLAR, RAB33B, PRKCQ, GABARAP, GABARAPL1, GABARAPL2, MAP1LC3C, MAP1LC3B, MAP1LC3A, MAP1LC3B2, ATG4A, ATG4B, ATG4C, ATG4D, LAMP1, LAMP2, RAB7A, RAB7B, VAMP8, SNAP29, CTSD, CTSL, CTSB
## 78 CHRNA7, ARRB1, ARRB2, SRC, RAF1, RB1, E2F1, BIRC5, XIAP, CDC6, CDC25A, JAK2, STAT3, IKBKE, CCND1, CHRNA4, CHRNB2, CHRNA3, CHRNB4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNA1B, CACNA1A, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, NFKB1, RELA, HRAS, KRAS, NRAS, MAP2K1, MAP2K2, MAPK1, MAPK3, FOS, JUN, MYC, BCL2, PRKCA, PRKCB, PRKCG, VEGFA, FGF2, ADRB1, ADRB2, ADRB3, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, GNAI1, GNAI3, GNAI2, BAD, CHRNA9, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, ESR1, ESR2, VDR, CCND3, EGFR, GRB2, SOS1, SOS2, EIF4EBP1, RPS6KB1, RPS6KB2, PAQR7, PAQR8, PAQR5, PGR, TNFSF11, STAT5A, STAT5B, BCL6, KLF5, KLF4, WNT1, NOTCH2, JAG1, MIR141, MIR29A, MIR29B1, MIR29B2, MIR29C, AR, MIRLET7A1, MIRLET7A2, MIRLET7A3, MIRLET7B, MIRLET7D, MIRLET7E, MIRLET7F1, MIRLET7F2, MIRLET7G, MIRLET7I, EGF, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, DLL3, DLL1, DLL4, PTGES3, AIPL1, AIP, AHR, HSP90AA1, HSP90AB1, HSP90B1, KPNA1, KPNA2, KPNA7, KPNA3, KPNA4, KPNA6, KPNA5, KPNB1, ARNT, CYP1A1, CYP1B1, EPHX1, EPHX2, EPHX3, EPHX4, GSTA5, GSTA2, GSTA4, GSTO2, GSTM4, GSTT2, GSTT1, GSTM3, MGST1, MGST3, GSTM1, GSTM5, MGST2, GSTA1, GSTM2, GSTA3, GSTO1, GSTT2B, UGT2A1, UGT2A3, UGT2B17, UGT2B11, UGT2B28, UGT1A6, UGT1A4, UGT1A1, UGT1A3, UGT2B10, UGT1A9, UGT2B7, UGT1A10, UGT1A8, UGT1A5, UGT2B15, UGT1A7, UGT2B4, UGT2A2, CYP2B6, NR1I3, RXRA, RXRB, RXRG, CYP3A4, CYP1A2, PPARA
## 80 SLC2A1, SLC2A2, GCK, PKM, PDHA2, PDHA1, PDHB, PDK1, TP53, SCO2, SLC1A5, SIRT3, SLC16A3, SIRT6, MYC, HIF1A, KIT, MET, RET, EGFR, ERBB2, NTRK1, NTRK3, PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3, FLT3, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, GLS2, GLS, G6PD, HK3, HK1, HK2, HKDC1, PFKM, PFKP, PFKL, PGAM1, PGAM2, PGAM4, LDHAL6A, LDHAL6B, LDHA, LDHB, LDHC, IDH1, IDH2, TIGAR, PTEN, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, SLC7A5
## 142 IL6, IL6R, STAT3, TLR4, IFNG, IFNGR1, IFNGR2, RELA, NFKB1, INS, EGF, IGF1, INSR, EGFR, IGF1R, ERBB2, MAP2K1, MAP2K2, MAPK1, MAPK3, MKNK1, MKNK2, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MTOR, EIF4EBP1, EIF4E, EIF4E2, EIF4E1B, RPS6KB1, RPS6KB2, RPS6, HIF1A, VHL, RBX1, ELOC, ELOB, CUL2, EGLN1, EGLN3, EGLN2, ARNT, CREBBP, EP300, CYBB, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, CAMK2A, CAMK2D, CAMK2B, CAMK2G, TIMP1, LTBR, EPO, TF, TFRC, VEGFA, FLT1, SERPINE1, ANGPT1, ANGPT2, ANGPT4, TEK, EDN1, NOS2, NOS3, HMOX1, NPPA, SLC2A1, PDK1, HK3, HK1, HK2, HKDC1, PFKM, PFKP, PFKL, GAPDH, ALDOC, ALDOA, ALDOB, ENO3, ENO2, ENO1, ENO4, PGK2, PGK1, PFKFB3, LDHAL6A, LDHAL6B, LDHA, LDHB, LDHC, BCL2, CDKN1A, CDKN1B, PDHA2, PDHA1, PDHB
## 163 AMY1C, AMY2A, AMY1A, AMY2B, AMY1B, LCT, MGAM, MGAM2, SI, SLC5A1, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, SLC2A2, HK3, HK1, HK2, HKDC1, SLC37A4, G6PC1, G6PC2, G6PC3, SLC2A5, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, AKT1, AKT2, AKT3, CACNA1D, PRKCB, TAS1R2, TAS1R3, GNAT3, PLCB1, PLCB2, PLCB3, PLCB4
## 84 BCL2L13, EIF2AK3, ATF4, MAPK8, MAPK10, MAPK9, JUN, PINK1, TOMM7, PRKN, UBA52, RPS27A, UBB, UBC, MFN1, MFN2, RHOT1, RHOT2, USP8, USP15, USP30, TAX1BP1, SQSTM1, CALCOCO2, OPTN, NBR1, TBK1, GABARAP, GABARAPL1, GABARAPL2, MAP1LC3C, MAP1LC3B, MAP1LC3A, MAP1LC3B2, AMBRA1, ATG5, ATG9B, ATG9A, MITF, TFEB, TFE3, BECN1, BECN2, BCL2L1, PGAM5, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, SRC, ULK1, FUNDC1, HIF1A, E2F1, RELA, BNIP3, HRAS, KRAS, NRAS, MRAS, RRAS, RRAS2, TP53, BNIP3L, FOXO3, CITED2, SP1, TBC1D15, TBC1D17, RAB7A, RAB7B, FIS1
## 87 TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD2, SMAD3, CDKN2B, CDK4, CDK6, CCND1, CCND2, CCND3, RB1, RBL1, RBL2, E2F1, E2F2, E2F3, E2F4, E2F5, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, FOXO1, FOXO3, CDKN1A, CDK2, CCNE1, CCNE2, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, KIR2DL4, KRAS, NRAS, RRAS, RRAS2, MRAS, HRAS, AKT1, AKT2, AKT3, TSC1, TSC2, RHEB, MTOR, PTEN, SIRT1, CCNA2, CCNA1, MYBL2, LIN9, LIN37, LIN52, LIN54, RBBP4, FOXM1, MYC, CDKN2A, MDM2, TP53, RASSF5, BTRC, FBXW11, HIPK3, HIPK1, HIPK2, HIPK4, PPP1CA, PPP1CB, PPP1CC, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, ETS1, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, GADD45A, GADD45B, GADD45G, CDK1, CCNB1, CCNB2, CCNB3, MRE11, RAD50, NBN, ATM, CHEK2, RAD9A, RAD9B, RAD1, HUS1, ATR, CHEK1, CDC25A, SQSTM1, GATA4, TRAF3IP2, NFKB1, RELA, IL1A, IL6, CXCL8, IGFBP3, SERPINE1, EIF4EBP1, MAPKAPK2, ZFP36L1, ZFP36L2, CACNA1D, TRPV4, TRPM7, CAPN1, CAPN2, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, NFATC4, ITPR1, ITPR2, ITPR3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPID, VDAC1, VDAC2, VDAC3, MCU
## 88 HIF1A, EGF, EGFR, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, FOS, JUN, EML4, ALK, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, PTEN, AKT1, AKT2, AKT3, MTOR, RPS6KB1, RPS6KB2, CHUK, IKBKB, IKBKG, NFKBIA, NFKBIB, NFKBIE, NFKB1, RELA, IFNG, IFNGR1, IFNGR2, JAK1, JAK2, STAT1, STAT3, TLR2, TLR4, TLR9, TIRAP, MYD88, TRAF6, NFATC1, NFATC2, NFATC3, TICAM1, TICAM2, CD274, PDCD1, PTPN6, PTPN11, BATF3, BATF, BATF2, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, CD4, LCK, CD3E, CD3G, CD247, CD3D, ZAP70, MAP3K3, MAP2K3, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, LAT, PLCG1, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, RASGRP1, CD28, PRKCQ
## 96 DLL3, DLL1, DLL4, NOTCH3, MAML3, MAML2, MAML1, RBPJL, RBPJ, NFKB1, RELA, IFNG, IFNGR1, IFNGR2, JAK1, JAK2, STAT1, IL12A, IL12B, IL12RB1, IL12RB2, TYK2, STAT4, TBX21, RUNX3, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, CD4, LCK, CD3E, CD3G, CD247, CD3D, ZAP70, LAT, PLCG1, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, PRKCQ, CHUK, IKBKB, IKBKG, NFKBIA, NFKBIB, NFKBIE, MAPK1, MAPK3, FOS, MAPK11, MAPK12, MAPK13, MAPK14, MAPK8, MAPK10, MAPK9, JUN, IL2, IL2RA, IL2RB, IL2RG, JAK3, STAT5A, STAT5B, IL4, IL4R, STAT6, GATA3, IL5, IL13, MAF, JAG1, JAG2, NOTCH1, NOTCH2
## 103 CD3D, CD3E, CD3G, CD247, CD4, CD8A, CD8B, CD8B2, PTPRC, LCK, FYN, ZAP70, LCP2, LAT, ITK, TEC, NCK1, NCK2, VAV3, VAV1, VAV2, GRAP2, GRB2, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, RHOA, CDC42, DLG1, MAPK11, MAPK12, MAPK13, MAPK14, PLCG1, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, SOS1, SOS2, RASGRP1, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, FOS, JUN, PRKCQ, CARD11, BCL10, MALT1, MAP3K7, MAP2K7, MAPK8, MAPK10, MAPK9, CHUK, IKBKB, IKBKG, NFKB1, RELA, NFKBIA, NFKBIB, NFKBIE, CD28, ICOS, CD40LG, PIK3R1, PIK3R2, PIK3R3, PIK3CA, PIK3CD, PIK3CB, PDPK1, AKT1, AKT2, AKT3, MAP3K8, MAP3K14, GSK3B, PDCD1, CTLA4, PTPN6, CBLB, IL2, IL4, IL5, IL10, IFNG, CSF2, TNF, CDK4
## 132 IL1B, IL1R1, IL1RAP, MAPK11, MAPK12, MAPK13, MAPK14, MTOR, IRF4, TGFB1, TGFBR1, TGFBR2, SMAD2, SMAD3, SMAD4, IL21, IL21R, IL2RG, JAK1, JAK3, IL6, IL6R, IL6ST, JAK2, IL23A, IL23R, IL12RB1, TYK2, STAT3, RORC, RORA, HIF1A, HSP90AA1, HSP90AB1, AHR, IL17A, IL17F, IL22, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, CD4, LCK, CD3E, CD3G, CD247, CD3D, ZAP70, LAT, PLCG1, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC1, NFATC2, NFATC3, PRKCQ, CHUK, IKBKB, IKBKG, NFKBIA, NFKBIB, NFKBIE, NFKB1, RELA, MAPK1, MAPK3, FOS, MAPK8, MAPK10, MAPK9, JUN, IL4, IL4R, STAT6, GATA3, RUNX1, IL27, EBI3, IL27RA, IFNG, IFNGR1, IFNGR2, STAT1, TBX21, IL2, IL2RA, IL2RB, STAT5A, STAT5B, FOXP3, RARA, RXRA, RXRB, RXRG
## 90 TBXA2R, F2, F2R, F2RL3, GNA13, ARHGEF1, ARHGEF12, RHOA, ROCK1, ROCK2, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, MYL12B, MYL12A, P2RX1, ORAI1, ITPR1, ITPR2, ITPR3, STIM1, MYLK, MYLK2, MYLK3, MYLK4, P2RY1, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCZ, PRKCI, RASGRP1, RASGRP2, RAP1A, RAP1B, APBB1IP, TLN1, TLN2, ITGA2B, ITGB3, FERMT3, FGA, FGB, FGG, P2RY12, GNAI1, GNAI3, GNAI2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PTGIR, GNAS, PIK3CG, PIK3R5, PIK3R6, PRKACA, PRKACB, PRKACG, VASP, ACTG1, ACTB, SRC, ARHGAP35, FCGR2A, SYK, COL1A1, COL1A2, COL3A1, GP6, FCER1G, LYN, FYN, ITGA2, ITGB1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, LCP2, PLCG2, BTK, VWF, GP5, GP1BA, GP1BB, GP9, AKT1, AKT2, AKT3, NOS3, GUCY1A2, GUCY1A1, GUCY1B1, PRKG1, PRKG2, MAPK11, MAPK12, MAPK13, MAPK14, MAPK1, MAPK3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PTGS1, TBXAS1, SNAP23, VAMP8
## 92 TH, DDC, SLC18A1, SLC18A2, MAOB, MAOA, SLC6A3, DRD1, GNAS, GRM2, GRM3, GNAI1, GNAI3, GNAI2, DRD2, ADCY5, PRKACA, PRKACB, PRKACG, GPSM1, RGS9, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, PDYN, BDNF, JUN, FOSB, NFKB1, RELA, CDK5, CDK5R1, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, DLG4, PPP1R1B, GRIA2
## 116 TH, DDC, SLC18A1, SLC18A2, MAOB, MAOA, SLC6A3, CACNA1C, CACNA1D, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, GRIA1, GRIA2, GRIA3, GRIA4, DRD1, PRKCA, PRKCB, PRKCG, STX1A, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK4, GNAS, ADCY5, PRKACA, PRKACB, PRKACG, PPP1R1B, PPP1CA, PPP1CB, PPP1CC, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, PDYN, ARC, FOS, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, JUN, FOSB, SIRT1, HDAC1, HDAC2
## 145 TH, DDC, SLC18A1, SLC18A2, MAOB, MAOA, SLC6A3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HDAC10, HDAC11, H2AX, H2AC20, H2AC12, H2AC1, H2AC25, H2AB3, H2AC8, H2AC4, MACROH2A2, MACROH2A1, H2AC19, H2AJ, H2AB1, H2AC17, H2AC18, H2AC11, H2AC21, H2AZ2, H2AC7, H2AZ1, H2AC15, H2AC6, H2AC13, H2AC14, H2AC16, H2AB2, H2BC15, H2BC9, H2BC14, H2BW1, H2BC1, H2BC18, H2BC17, H2BC3, H2BC8, H2BC13, H2BC4, H2BC5, H2BC6, H2BC10, H2BC21, H2BC11, H2BC12, H2BC26, H2BC7, H2BW2, H2BK1, H2BC12L, H3-5, H3-3B, H3C4, H3C3, H3C1, H3-3A, H3-4, H3C14, H3C15, H3C13, H3C6, H3C11, H3C8, H3C12, H3C10, H3C2, H3C7, H4C16, H4C15, H4C9, H4C4, H4C6, H4C12, H4C11, H4C3, H4C8, H4C2, H4C5, H4C13, H4C14, H4C1, H4C7, HAT1, DRD1, GNAS, DRD2, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, SLC29A3, SLC29A1, SLC29A2, ADORA2A, ADORA2B, ADCY5, PRKACA, PRKACB, PRKACG, CREB1, ATF2, ATF4, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, ATF6B, CRH, NPY, BDNF, NTRK2, SHC1, SHC2, SHC3, SHC4, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAPK1, MAPK3, PDYN, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMKK1, CAMKK2, CAMK4, FOSB, PPP1R1B, PPP1CA, PPP1CB, PPP1CC, PKIA
## 93 ADRB1, ADRB2, ADRB3, ADCYAP1, ADCYAP1R1, AQP1, PTGER2, PTGER4, GNAS, ADCY5, ADCY6, PRKACA, PRKACB, PRKACG, CREB1, KCNMA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B, REN, ADORA1, GNAI1, GNAI3, GNAI2, ORAI1, CLCA1, CLCA2, CLCA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, KCNJ2, EDN1, EDN2, EDN3, EDNRA, AGTR1, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, GUCY1A2, GUCY1A1, GUCY1B1, NPPA, NPR1, PRKG2, CTSB, AGT, ACE
## 97 GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, NOS1, MAPK1, MAPK3, RPS6KA5, CREB1, ITPR1, ITPR3, RYR1, RYR2, RYR3, NOS1AP, RASD1, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, GRIA1, GRIA2, GRIA3, GRIA4, CACNA1G, CACNA1H, CACNA1I, ADCYAP1, ADCYAP1R1, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, ADCY10, PRKACA, PRKACB, PRKACG, GUCY1A2, GUCY1A1, GUCY1B1, PRKG1, PRKG2, CACNA1C, CACNA1D, MTNR1B, MTNR1A, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, KCNJ3, KCNJ5, KCNJ6, KCNJ9, PER1, PER2, PER3, FOS
## 122 SLC38A1, SLC38A2, GLS2, GLS, SLC17A6, SLC17A8, SLC17A7, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, DLG4, DLGAP1, SHANK3, SHANK1, SHANK2, TRPC1, GRM1, GRM5, HOMER1, HOMER2, HOMER3, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, ITPR1, ITPR2, ITPR3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PLD1, PLD2, MAPK1, MAPK3, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, GRM2, GRM3, GRM4, GRM6, GRM7, GRM8, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, GRK2, GRK3, KCNJ3, CACNA1A, SLC1A2, SLC1A7, SLC1A1, SLC1A6, CACNA1C, CACNA1D, SLC1A3, GLUL, SLC38A3
## 124 GRIA1, GRIA2, ADCY1, ADCY8, PRKACA, PRKACB, PRKACG, PPP1R1A, PPP1CA, PPP1CB, PPP1CC, CAMK2A, CAMK2D, CAMK2B, CAMK2G, RAPGEF3, RAP1A, RAP1B, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, CACNA1C, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CREBBP, EP300, ATF4, CAMK4, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, RPS6KA3, RPS6KA1, RPS6KA2, RPS6KA6, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, GRM1, GRM5, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4
## 129 ADRB1, ADRB2, ADRB3, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, VAMP2, ADRA1A, ADRA1B, ADRA1D, CHRM3, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, ITPR1, ITPR2, ITPR3, RYR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, NOS1, GUCY1A2, GUCY1A1, GUCY1B1, PRKG1, PRKG2, CD38, BST1, BEST2, AQP5, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, ATP2B1, ATP2B3, ATP2B4, ATP2B2, SLC12A2, KCNN4, KCNMA1, SLC4A2, SLC9A1, TRPV6, MUC5B, MUC7, AMY1C, AMY2A, AMY1A, AMY2B, AMY1B, PRH2, PRH1, PRB1, PRB2, DMBT1, CST1, CST2, CST3, CST4, CST5, HTN1, HTN3, STATH, LYZ, LPO, CAMP
## 139 GJA1, GJD2, LPAR1, GNAI1, GNAI3, GNAI2, PDGFA, PDGFB, PDGFC, PDGFD, EGF, PDGFRA, PDGFRB, EGFR, GRB2, SOS1, SOS2, HRAS, KRAS, NRAS, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, SRC, MAP3K2, MAP2K5, MAPK7, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3, TUBB6, TUBB, TUBB1, TUBB2A, TUBB3, TUBB4A, TUBB8, TUBB2B, TUBB4B, CSNK1D, CDK1, TJP1, ADRB1, DRD1, GNAS, DRD2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, HTR2A, HTR2B, HTR2C, GRM1, GRM5, GNA11, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, GUCY1A2, GUCY1A1, GUCY1B1, PRKG1, PRKG2
## 141 NOS1, GUCY1A2, GUCY1A1, GUCY1B1, PRKG1, PRKG2, PPP1R17, PPP2R1B, PPP2R1A, PPP2CA, PPP2CB, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, GRID2, GRM1, GNAI1, GNAI3, GNAI2, GNAO1, GNAZ, GNAS, GNA12, GNA13, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PRKCA, PRKCB, PRKCG, GNAQ, GNA11, PLCB1, PLCB2, PLCB3, PLCB4, GRIA1, GRIA2, GRIA3, LYN, CACNA1A, ITPR1, ITPR2, ITPR3, RYR1, CRH, CRHR1, IGF1, IGF1R
## 149 TPH2, TPH1, DDC, SLC18A1, SLC18A2, CACNA1C, CACNA1D, CACNA1F, CACNA1S, HTR2A, HTR2B, HTR2C, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, MAPK1, MAPK3, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2D6, CYP2D7, CYP2J2, CYP4X1, ALOX5, ALOX12, ALOX12B, ALOX15, ALOX15B, PTGS1, PTGS2, HTR3A, HTR3E, HTR3D, HTR3C, HTR3B, HTR4, HTR6, HTR7, GNAS, ADCY5, PRKACA, PRKACB, PRKACG, KCNN2, KCND2, GABRB1, GABRB3, GABRB2, RAPGEF3, APP, HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR5A, GNAI1, GNAI3, GNAI2, GNAO1, GNB1, GNB2, GNB3, GNB4, GNB5, GNG2, GNG3, GNG4, GNG5, GNG7, GNG8, GNG10, GNG11, GNG12, GNG13, GNGT1, GNGT2, CASP3, DUSP1, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, CACNA1A, CACNA1B, KCNJ3, KCNJ6, KCNJ9, KCNJ5, TRPC1, SLC6A4, MAOB, MAOA
## 151 CHRM3, GAST, CCKBR, GNAQ, PLCB1, PLCB2, PLCB3, PLCB4, PRKCA, PRKCB, PRKCG, EZR, ACTG1, ACTB, ITPR1, ITPR2, ITPR3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, MYLK, MYLK2, MYLK3, MYLK4, HRH2, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, SST, SSTR2, GNAI1, GNAI3, GNAI2, PRKACA, PRKACB, PRKACG, ATP4A, ATP4B, KCNE2, KCNQ1, KCNJ1, KCNJ2, KCNJ10, KCNJ15, KCNJ16, CFTR, KCNK2, KCNK10, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, SLC9A1, SLC9A4, CA2, SLC26A7, SLC4A2
## 157 ADRA1A, ADRA1B, ADRA1D, AGT, AGTR1, EDN1, EDN2, EDN3, EDNRA, AVP, AVPR1A, AVPR1B, GNAQ, GNA11, PLA2G10, PLA2G2D, PLA2G2E, PLA2G3, PLA2G2F, PLA2G12A, PLA2G12B, PLA2G1B, PLA2G5, PLA2G2A, PLA2G2C, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, PLA2G6, KCNMA1, KCNU1, KCNMB1, KCNMB2, KCNMB3, KCNMB4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, MYLK, MYLK2, MYLK3, MYLK4, MYL6B, MYL6, MYL9, MYH9, MYH10, MYH11, MYH14, PLCB1, PLCB2, PLCB3, PLCB4, ITPR1, ITPR2, ITPR3, PRKCA, PRKCB, PRKCG, PRKCD, PRKCE, PRKCH, PRKCQ, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, CALD1, ACTA2, ACTG2, PPP1R14A, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, PPP1R12B, PPP1R12C, GNA12, GNA13, ARHGEF12, ARHGEF1, ARHGEF11, RHOA, ROCK1, ROCK2, ADORA2A, ADORA2B, PTGIR, CALCA, CALCB, ADM, ADM2, CALCRL, RAMP1, RAMP2, RAMP3, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, NPPA, NPPB, NPR1, NPPC, NPR2, PRKG1, IRAG1, GUCY1A2, GUCY1A1, GUCY1B1
## 94 SLC8A1, SLC8A2, SLC8A3, ATP2B1, ATP2B3, ATP2B4, ATP2B2, CHRM1, CHRM3, CHRM5, ADORA2A, ADORA2B, ADRB1, ADRB2, ADRB3, DRD1, DRD5, HRH2, HTR4, HTR5A, HTR6, HTR7, GNAS, GNAL, ADCY1, ADCY2, ADCY3, ADCY4, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, PLN, ATP2A1, ATP2A3, ATP2A2, HRC, STIM1, STIM2, ORAI1, ORAI2, ORAI3, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNA1A, CACNA1B, CACNA1E, CACNA1G, CACNA1H, CACNA1I, CHRNA7, P2RX1, P2RX2, P2RX3, P2RX4, P2RX5, P2RX7, P2RX6, GRIN1, GRIN2A, GRIN2C, GRIN2D, RYR1, RYR2, RYR3, TRDN, CASQ1, CASQ2, ASPH, CYSLTR1, CYSLTR2, CHRM2, ADRA1A, ADRA1B, ADRA1D, AGTR1, EDNRA, EDNRB, F2R, GRM1, GRM5, GRPR, HRH1, HTR2A, HTR2B, HTR2C, LHCGR, NTSR1, OXTR, AVPR1A, AVPR1B, LTB4R2, PTAFR, PTGER1, PTGER3, PTGFR, BDKRB1, BDKRB2, TACR1, TACR2, TACR3, TBXA2R, TRHR, CCKAR, CCKBR, CXCR4, GNAQ, GNA11, GNA14, GNA15, EGF, PDGFA, PDGFB, PDGFC, PDGFD, FGF1, FGF2, FGF3, FGF4, FGF17, FGF6, FGF7, FGF8, FGF9, FGF10, FGF16, FGF5, FGF18, FGF20, FGF22, FGF19, FGF21, FGF23, VEGFA, VEGFB, VEGFC, VEGFD, NGF, HGF, MST1, GDNF, EGFR, ERBB2, ERBB3, ERBB4, PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3, FGFR4, FLT1, FLT4, KDR, NTRK1, NTRK2, NTRK3, MET, MST1R, RET, IGH, PLCD1, PLCD3, PLCD4, PLCB1, PLCB2, PLCB3, PLCB4, PLCG1, PLCG2, PLCE1, PLCZ1, ITPR1, ITPR2, ITPR3, CD38, TPCN1, TPCN2, MCOLN1, MCOLN2, MCOLN3, SPHK1, SPHK2, MCU, VDAC1, VDAC2, VDAC3, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPIF, TNNC1, TNNC2, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, PHKG1, PHKG2, PHKB, PHKA2, PHKA1, MYLK, MYLK2, MYLK3, MYLK4, CAMK1D, CAMK1G, CAMK1, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NOS1, NOS2, NOS3, PDE1A, PDE1B, PDE1C, PTK2B, ITPKB, ITPKA, ITPKC, PRKCA, PRKCB, PRKCG
## 104 HSP90AA1, HSP90AB1, HSP90B1, NOS3, CAV1, CAV2, CAV3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, GPC1, SDC1, SDC2, SDC4, TRPV4, KEAP1, NFE2L2, HMOX1, GSTA5, GSTA2, GSTA4, GSTO2, GSTM4, GSTT2, GSTT1, GSTM3, MGST1, MGST3, GSTM1, GSTM5, MGST2, GSTA1, GSTM2, GSTA3, GSTO1, GSTT2B, GSTP1, NQO1, SQSTM1, TXN, TXN2, NPPC, ASS1, THBD, PLAT, CDH5, KDR, CTNNB1, PRKAA1, PRKAA2, PECAM1, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, MAP2K5, MAPK7, MEF2A, MEF2C, KLF2, ITGA2B, ITGAV, ITGB3, SRC, PTK2, ARHGEF2, RHOA, ACTG1, ACTB, DUSP1, MIR10A, TNFRSF1A, IL1R1, IL1R2, MAP3K7, IKBKG, CHUK, IKBKB, NFKB1, RELA, MAP3K5, MAP2K4, MAP2K7, MAPK8, MAPK10, MAPK9, MAP2K6, MAPK11, MAPK12, MAPK13, MAPK14, FOS, JUN, MMP2, MMP9, CTSL, CCL2, VCAM1, ICAM1, SELE, TNF, IL1A, IL1B, IFNG, PDGFA, PDGFB, EDN1, VEGFA, BMP4, BMPR2, ACVR2A, ACVR2B, ACVR1, BMPR1A, BMPR1B, NOX1, CYBA, NCF1, NCF2, RAC1, RAC2, RAC3, PRKCZ, PIAS4, TP53, SUMO3, SUMO2, SUMO1, SUMO4, BCL2
## 105 FGFR3, HRAS, KRAS, NRAS, ARAF, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, RPS6KA5, MYC, RASSF1, DAPK1, DAPK3, DAPK2, CDKN2A, MDM2, TP53, CDKN1A, CCND1, CDK4, RB1, E2F1, E2F2, E2F3, THBS1, HBEGF, MMP2, MMP9, UPK3A, SRC, EGF, ERBB2, EGFR, TYMP, VEGFA, MMP1, CXCL8, CDH1
## 159 RET, CCDC6, NCOA4, NTRK1, TPM3, TPR, TFG, HRAS, NRAS, KRAS, BRAF, MAP2K1, MAP2K2, MAPK1, MAPK3, PAX8, PPARG, RXRA, RXRB, RXRG, TP53, CDKN1A, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK, CDH1, CTNNB1, TCF7, TCF7L1, TCF7L2, LEF1, MYC, CCND1
## 114 TNF, TNFRSF1A, TRADD, TRAF2, TRAF5, RIPK1, BIRC2, BIRC3, XIAP, RBCK1, RNF31, SHARPIN, SPATA2L, SPATA2, CYLD, FADD, CASP8, CFLAR, RIPK3, CYBB, CAMK2A, CAMK2D, CAMK2B, CAMK2G, SLC25A4, SLC25A5, SLC25A6, SLC25A31, PPID, VDAC1, VDAC2, VDAC3, GLUD2, GLUD1, GLUL, PYGL, PYGM, PYGB, MAPK8, MAPK10, MAPK9, FTH1, FTL, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, ALOX15, CAPN1, CAPN2, SMPD1, MLKL, PGAM5, DNM1L, NLRP3, PYCARD, CASP1, IL1B, CHMP2A, CHMP2B, CHMP3, RNF103-CHMP3, CHMP4B, CHMP4A, CHMP4C, CHMP6, VPS4B, VPS4A, CHMP1B, CHMP1A, CHMP5, CHMP7, TRPM7, IL1A, IL33, HMGB1, TNFSF10, TNFRSF10A, TNFRSF10B, FASLG, FAS, FAF1, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNG, IFNAR1, IFNAR2, IFNGR1, IFNGR2, JAK1, JAK2, JAK3, TYK2, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6, IRF9, EIF2AK2, TLR4, TICAM2, TICAM1, TLR3, ZBP1, USP21, SQSTM1, HSP90AA1, HSP90AB1, TNFAIP3, PARP1, BID, BAX, AIFM1, H2AX, H2AC20, H2AC12, H2AC1, H2AC25, H2AB3, H2AC8, H2AC4, MACROH2A2, MACROH2A1, H2AC19, H2AJ, H2AB1, H2AC17, H2AC18, H2AC11, H2AC21, H2AZ2, H2AC7, H2AZ1, H2AC15, H2AC6, H2AC13, H2AC14, H2AC16, H2AB2, PPIA, BCL2
## 117 TNFRSF1A, FADD, CASP8, CASP7, CASP3, BID, BCL2L11, PMAIP1, BBC3, BCL2, BCL2L1, BAX, BAK1, CYCS, APAF1, CASP9, DIABLO, HTRA2, SEPTIN4, BIRC2, BIRC3, XIAP, BIRC5, MAPK8, MAPK10, MAPK9, BOK, BIRC7, NGFR, BECN1, BECN2, BIRC6
## 118 EGF, PDGFA, PDGFB, PDGFC, PDGFD, KITLG, INS, EGFR, PDGFRA, PDGFRB, KIT, INSR, GRB2, GAB1, GAB2, SHC1, SHC2, SHC3, SHC4, PTPN11, SOS1, SOS2, HRAS, KRAS, NRAS, MRAS, RRAS, RRAS2, RALGDS, RALA, RALB, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, TSC1, TSC2, RHEB, MTOR, RHOA, ARF1, ARF6, PLCG1, PLCG2, IGH, FCER1A, MS4A2, FCER1G, FYN, SYK, PRKCA, PLD1, PLD2, PLA2G4E, PLA2G4A, JMJD7-PLA2G4B, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4F, AGPAT1, AGPAT2, AGPAT3, AGPAT4, AGPAT5, SPHK1, SPHK2, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PIP5K1C, PIP5K1A, PIP5K1B, DGKZ, DGKD, DGKI, DGKA, DGKE, DGKB, DGKH, DGKG, DGKQ, DGKK, PLPP1, PLPP3, PLPP2, F2, AGT, AVP, CXCL8, AGTR1, F2R, GRM1, GRM2, GRM3, GRM4, GRM5, GRM6, GRM7, GRM8, AVPR1A, AVPR1B, AVPR2, LPAR1, LPAR2, LPAR3, LPAR4, LPAR5, LPAR6, PTGFR, CXCR1, CXCR2, PLCB1, PLCB2, PLCB3, PLCB4, GNA12, PTK2B, GNA13, PIK3CG, PIK3R5, PIK3R6, CYTH3, CYTH4, CYTH2, CYTH1, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, RAPGEF3, RAPGEF4, DNM1, DNM3, DNM2
## 123 CRB3, CLDN4, CLDN3, CLDN7, CLDN19, CLDN16, CLDN14, CLDN15, CLDN17, CLDN20, CLDN11, CLDN18, CLDN22, CLDN5, CLDN10, CLDN8, CLDN6, CLDN2, CLDN1, CLDN9, CLDN23, CLDN34, CLDN25, CLDN24, OCLN, F11R, JAM2, JAM3, BVES, CDC42, PARD6A, PARD6G, PARD6B, PALS1, MPP4, TJP3, PATJ, MPDZ, PRKCZ, PRKCI, AMOT, AMOTL1, AMOTL2, ARHGAP17, RAC1, NF2, LLGL2, LLGL1, DLG1, SCRIB, PPP2CA, PPP2CB, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PARD3, TIAM1, TJP1, TJAP1, DLG2, DLG3, NEDD4, NEDD4L, CGN, CGNL1, ARHGEF2, RHOA, GATA4, MARVELD3, MAP3K1, MAPK8, MAPK10, MAPK9, JUN, CD1A, CD1B, CD1C, CD1D, CD1E, CFTR, CDK4, YBX3, SYMPK, PCNA, CCND1, ERBB2, RUNX1, HSPA4, NHERF1, EZR, RDX, MSN, PRKCE, ACTG1, ACTB, CACNA1D, MAP3K5, MAP2K7, SRC, CTTN, HCLS1, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, WHAMM, WAS, VASP, PRKACA, PRKACB, PRKACG, RAB13, ARHGEF18, ROCK1, ROCK2, MYL2, EPB41L4B, STK11, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, MYH9, MYH10, MYH11, MYH14, MYL6B, MYL6, MYL9, MYL12B, MYL12A, IGSF5, MAGI1, SYNPO, ACTN1, ACTN4, MICALL2, RAB8A, RAB8B, RAPGEF6, RAP1A, ITGB1, AFDN, TJP2, RAPGEF2, RAP2C, MARVELD2, TUBA1B, TUBA4A, TUBA3C, TUBA1A, TUBA1C, TUBA8, TUBA3E, TUBA3D, TUBAL3
## 125 CHRD, NOG, NBL1, MICOS10-NBL1, GREM1, GREM2, THBS1, DCN, FMOD, LEFTY1, LEFTY2, FST, BMP2, BMP4, BMP6, INHBB, BMP5, BMP7, BMP8B, BMP8A, GDF5, GDF6, GDF7, AMH, THSD4, FBN1, LTBP1, TGFB1, TGFB2, TGFB3, INHBA, INHBC, INHBE, NODAL, NEO1, HJV, BMPR1A, BMPR1B, ACVR1, BMPR2, ACVR2A, RGMA, RGMB, AMHR2, TGFBR1, TGFBR2, ACVR1B, ACVR2B, ACVR1C, IGSF1, BAMBI, SMAD1, SMAD5, SMAD9, SMAD2, SMAD3, SMAD4, SMAD6, SMAD7, SMURF1, SMURF2, ZFYVE9, ZFYVE16, HAMP, ID1, ID2, ID3, ID4, RBL1, E2F4, E2F5, TFDP1, CREBBP, EP300, SP1, TGIF1, TGIF2, MYC, CDKN2B, PITX2, RBX1, CUL1, SKP1, MAPK1, MAPK3, IFNG, TNF, RHOA, ROCK1, PPP2R1B, PPP2R1A, PPP2CA, PPP2CB, RPS6KB1, RPS6KB2
## 126 ARF6, PIP5K1C, PIP5K1A, PIP5K1B, PIP5KL1, PLD1, PLD2, DNM1, DNM3, DNM2, CLTA, CLTB, CLTC, CLTCL1, AP2A2, AP2A1, AP2B1, AP2M1, AP2S1, EHD2, TGFBR1, TGFBR2, ZFYVE9, ZFYVE16, PML, SMAD2, SMAD3, TFRC, EGFR, PDGFRA, FGFR2, FGFR3, FGFR4, IGF1R, CBL, CBLB, CBLC, SH3KBP1, SH3GL3, SH3GL2, SH3GL1, SH3GLB1, SH3GLB2, AMPH, BIN1, EPN1, EPN3, EPN2, EPS15, EPS15L1, SPART, NEDD4, NEDD4L, MDM2, TRAF6, RNF41, ITCH, SMURF1, SMURF2, WWP1, LDLR, LDLRAP1, DAB2, CCR5, CXCR1, CXCR2, CXCR4, GRK7, GRK1, GRK2, GRK3, GRK4, GRK5, GRK6, ARRB1, ARRB2, WASL, ACTR2, ACTR3B, ACTR3C, ACTR3, ARPC1B, ARPC1A, ARPC2, ARPC3, ARPC4, ARPC5, ARPC5L, WIPF2, WIPF1, WIPF3, HSPA8, HSPA1A, HSPA2, HSPA1L, HSPA1B, HSPA6, DNAJC6, WASHC4, WASHC5, WASHC2C, WASHC2A, WASHC1, WASHC3, CAPZA1, CAPZA2, CAPZA3, CAPZB, VPS29, VPS26B, VPS26A, VPS35, SNX12, SNX3, USP8, STAMBP, RAB7A, HGS, STAM2, STAM, TSG101, MVB12A, MVB12B, VPS28, VPS37D, VPS37A, VPS37B, VPS37C, SNF8, VPS36, VPS25, CHMP6, CHMP4B, CHMP4A, CHMP4C, CHMP3, RNF103-CHMP3, CHMP2A, CHMP2B, CHMP7, VPS4B, VPS4A, VTA1, CHMP1B, CHMP1A, CHMP5, IST1, PDCD6IP, SPG21, IGF2R, SNX1, SNX2, SNX32, SNX5, SNX6, SRC, HRAS, IL2RA, IL2RB, IL2RG, RHOA, HLA-A, HLA-B, HLA-C, HLA-F, HLA-G, HLA-E, FOLR1, FOLR2, FOLR3, CAV1, CAV2, CAV3, EHD3, EHD4, EEA1, RAB5A, RAB5B, RAB5C, RABEP1, RBSN, RAB4A, RUFY1, RUFY2, EHD1, VPS45, SNX4, RAB22A, RAB31, RAB10, RAB8A, RAB35, RAB11A, RAB11B, RAB11FIP2, RAB11FIP1, RAB11FIP5, ZFYVE27, KIF5A, KIF5B, KIF5C, RAB11FIP4, RAB11FIP3, PARD3, PARD6A, PARD6G, PARD6B, PRKCZ, PRKCI, CDC42, SMAP2, SMAP1, GIT1, GIT2, ASAP1, ASAP3, ASAP2, ACAP3, ACAP2, ACAP1, ARAP1, ARAP2, ARAP3, AGAP1, AGAP3, AGAP4, AGAP6, AGAP9, AGAP5, AGAP2, ARFGAP1, ARFGAP3, ARFGAP2, PSD3, PSD4, PSD, PSD2, IQSEC2, IQSEC1, IQSEC3, CYTH3, CYTH4, CYTH2, CYTH1, ARFGEF2, ARFGEF1, GBF1, ARF1, ARF3, ARF4, ARF5
## 136 CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNB1, CACNB2, CACNB3, CACNB4, CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, CACNG1, CACNG2, CACNG3, CACNG4, CACNG5, CACNG6, CACNG7, CACNG8, RYR2, ASPH, CASQ2, TRDN, HRC, ATP2A1, ATP2A3, ATP2A2, TNNC1, TNNI3, TNNT2, TPM1, TPM2, TPM3, TPM4, ACTC1, MYH7, MYH6, MYL2, MYL3, MYL4, UQCRFS1, CYTB, CYC1, UQCRC1, UQCRC2, UQCRH, UQCRHL, UQCRB, UQCRQ, UQCR10, UQCR11, COX3, COX1, COX2, COX4I2, COX4I1, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A1, COX7A2, COX7A2L, COX7B, COX7B2, COX7C, COX8C, COX8A, SLC8A1, SLC8A2, SLC8A3, SLC9A6, SLC9A7, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, SLC9A1
## 137 NTNG1, NTNG2, LRRC4C, LRRC4, NTN1, NTN3, NTN4, DCC, PLCG1, PLCG2, TRPC1, TRPC3, TRPC4, TRPC5, TRPC6, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, NFATC2, NFATC3, NFATC4, PTK2, FYN, SRC, RAC1, RAC2, RAC3, CDC42, ABLIM1, ABLIM3, ABLIM2, NCK1, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, BUB1B-PAK6, RHOA, ROCK1, ROCK2, UNC5A, UNC5B, UNC5C, UNC5D, PTPN11, RGMA, NEO1, MYL5, MYL9, MYL12B, MYL12A, ARHGEF12, LRIG2, EFNA1, EFNA2, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EFNB3, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, EPHB6, ABL1, ENAH, RASA1, NGEF, HRAS, KRAS, NRAS, MAPK1, MAPK3, NCK2, RGS3, CXCL12, CXCR4, GNAI1, GNAI3, GNAI2, SLIT1, SLIT2, SLIT3, ROBO1, ROBO2, ROBO3, SRGAP2, SRGAP1, SRGAP3, SEMA3A, SEMA3B, SEMA3C, SEMA3D, SEMA3E, SEMA3F, SEMA3G, PLXNA2, PLXNA3, PLXNA1, PLXNA4, NRP1, L1CAM, LIMK1, LIMK2, CFL1, CFL2, RHOD, RND1, FES, DPYSL5, DPYSL2, CDK5, GSK3B, SEMA4F, SEMA4D, SEMA4B, SEMA4C, SEMA4G, SEMA4A, SEMA5A, SEMA5B, SEMA6A, SEMA6B, SEMA6C, SEMA6D, PLXNB1, PLXNB2, PLXNB3, MET, RAF1, RRAS, SEMA7A, PLXNC1, ITGB1, SHH, PTCH1, SMO, PRKCA, ILK, BOC, WNT5A, WNT5B, FZD3, RYK, CAMK2A, CAMK2D, CAMK2B, CAMK2G, WNT4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, PDPK1, PARD3, PRKCZ, PARD6A, PARD6G, PARD6B, SSH1, SSH3, SSH2, BMP7, GDF7, BMPR2, BMPR1B
## 138 TLR2, TLR4, TLR5, NFKB1, RELA, NOD2, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, IFNG, IFNGR1, IFNGR2, STAT1, TBX21, IL4, IL5, IL12A, IL12B, IL12RB2, IL12RB1, STAT4, IL2, IL18, IL18R1, IL18RAP, JUN, TNF, IL6, IL1A, IL1B, TGFB1, TGFB2, TGFB3, SMAD2, SMAD3, STAT3, IL21, IL21R, IL23A, IL23R, RORC, RORA, FOXP3, IL17A, IL17F, IL22, IL4R, IL2RG, STAT6, GATA3, IL10, IL13, MAF, NFATC1
## 143 RORA, RORB, RORC, NR1D1, NR1D2, NFIL3, BMAL1, DBP, BHLHE40, BHLHE41, CSNK1D, CSNK1E, TPTEP2-CSNK1E, PER1, PER2, PER3, CRY1, CRY2, CLOCK, NPAS2, CREB1, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, RBX1, CUL1, SKP1, BTRC, FBXW11, FBXL3
## 156 ITGA1, ITGA2, ITGA2B, ITGA3, ITGA4, ITGA5, ITGA6, ITGA7, ITGA8, ITGA9, ITGA10, ITGA11, ITGAV, ITGB1, ITGB3, ITGB4, ITGB5, ITGB6, ITGB7, ITGB8, SGCD, SGCG, SGCA, SGCB, LAMA1, LAMA2, DAG1, DES, DMD, ACTG1, ACTB, TTN, TNNT2, TNNC1, TNNI3, ACTC1, TPM1, TPM2, TPM3, TPM4, MYBPC3, MYL3, MYL2, MYH7, MYH6, EMD, LMNA, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNB1, CACNB2, CACNB3, CACNB4, CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, CACNG1, CACNG2, CACNG3, CACNG4, CACNG5, CACNG6, CACNG7, CACNG8, RYR2, ATP2A1, ATP2A3, ATP2A2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG3, PRKAG2, ACE, IGF1, TGFB1, TGFB2, TGFB3, TNF, IL6, EDN1, AGT, SLC8A1, SLC8A2, SLC8A3
## 144 PTPN11, MET, PLCG1, PLCG2, TJP1, F11R, JAM2, JAM3, IGSF5, ADAM17, HBEGF, EGFR, CXCL8, CXCR1, CXCR2, ADAM10, SRC, LYN, CSK, RAC1, CDC42, MAPK11, MAPK12, MAPK13, MAPK14, PAK1, MAP2K4, MAPK8, MAPK10, MAPK9, JUN, MAP3K14, CHUK, IKBKB, IKBKG, NFKBIA, NFKB1, RELA, NOD1, CXCL1, CXCL2, CXCL3, CCL5, PTPRZ1, GIT1, CASP3, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C2, ATP6V1C1, ATP6V1D, ATP6V1E2, ATP6V1E1, ATP6V1F, ATP6V1G1, ATP6V1G3, ATP6V1G2, ATP6V0E1, ATP6V0E2, TCIRG1, ATP6V0A2, ATP6V0A4, ATP6V0A1, ATP6V0D1, ATP6V0D2, ATP6V1H, ATP6AP1, ATP6V0C, ATP6V0B
## 152 ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C2, ATP6V1C1, ATP6V1D, ATP6V1E2, ATP6V1E1, ATP6V1F, ATP6V1G1, ATP6V1G3, ATP6V1G2, ATP6V0E1, ATP6V0E2, TCIRG1, ATP6V0A2, ATP6V0A4, ATP6V0A1, ATP6V0D1, ATP6V0D2, ATP6V1H, ATP6AP1, ATP6V0C, ATP6V0B, KDELR1, KDELR2, KDELR3, PDIA4, ERO1A, SEC61A1, SEC61A2, SEC61B, SEC61G, ARF1, GNAS, ADCY3, ADCY9, PRKACA, PRKACB, PRKACG, CFTR, KCNQ1, SLC12A2, ACTG1, ACTB, PLCG1, PLCG2, PRKCA, TJP1, TJP2
## 148 PORCN, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, CER1, NOTUM, WIF1, SOST, DKK1, DKK2, DKK4, SERPINF1, SFRP1, SFRP2, FRZB, SFRP4, SFRP5, RSPO1, RSPO2, RSPO3, RSPO4, LGR4, LGR5, LGR6, RNF43, ZNRF3, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, LRP5, LRP6, BAMBI, APCDD1, APCDD1L, CSNK1E, TPTEP2-CSNK1E, CCDC88C, DVL3, DVL2, DVL1, FRAT1, FRAT2, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, NKD1, NKD2, CXXC4, SENP2, GSK3B, CTNNB1, AXIN1, AXIN2, APC, APC2, CSNK1A1L, CSNK1A1, TCF7, TCF7L1, TCF7L2, LEF1, CTNNBIP1, CBY1, CHD8, SOX17, CTBP1, CTBP2, TLE7, TLE1, TLE2, TLE3, TLE4, TLE6, CTNND2, CREBBP, EP300, RUVBL1, SMAD4, SMAD3, MAP3K7, NLK, MYC, JUN, FOSL1, CCND1, CCND2, CCND3, CCN4, PPARD, MMP7, PSEN1, PRKACA, PRKACB, PRKACG, TP53, SIAH1, CACYBP, SKP1, TBL1X, TBL1Y, TBL1XR1, BTRC, FBXW11, CUL1, RBX1, GPC4, ROR1, ROR2, RYK, VANGL2, VANGL1, PRICKLE1, PRICKLE2, PRICKLE4, PRICKLE3, INVS, DAAM1, DAAM2, RHOA, ROCK2, RAC1, RAC2, RAC3, MAPK8, MAPK10, MAPK9, PLCB1, PLCB2, PLCB3, PLCB4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, PRKCA, PRKCB, PRKCG, NFATC1, NFATC2, NFATC3, NFATC4
## 162 CRB2, CRB1, PARD3, PARD6A, PARD6G, PARD6B, PRKCZ, PRKCI, PATJ, PALS1, AMOT, YAP1, WWTR1, CDH1, LIMD1, AJUBA, WTIP, NF2, WWC1, FRMD1, FRMD6, SAV1, STK3, RASSF6, RASSF1, PPP2CA, PPP2CB, PPP2R1B, PPP2R1A, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, LATS2, LATS1, MOB1A, MOB1B, PPP1CA, PPP1CB, PPP1CC, TP53BP2, LLGL2, LLGL1, SCRIB, DLG1, DLG2, DLG3, DLG4, DLG5, CSNK1D, CSNK1E, TPTEP2-CSNK1E, BTRC, FBXW11, TP73, BBC3, TEAD1, TEAD4, TEAD3, TEAD2, CCN2, GLI2, AREG, BIRC5, AFP, ITGB2, FGF1, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, SMAD7, SMAD2, SMAD3, SMAD4, SERPINE1, BMP2, BMP4, BMP5, BMP6, BMP7, BMP8B, BMP8A, GDF5, GDF6, GDF7, AMH, BMPR1A, BMPR1B, BMPR2, SMAD1, ID1, ID2, WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10B, WNT10A, WNT11, WNT16, FZD1, FZD7, FZD2, FZD3, FZD4, FZD5, FZD8, FZD6, FZD10, FZD9, DVL3, DVL2, DVL1, YWHAZ, YWHAB, YWHAQ, YWHAE, YWHAH, YWHAG, GSK3B, CTNNB1, APC, APC2, AXIN1, AXIN2, NKD1, NKD2, TCF7, TCF7L1, TCF7L2, LEF1, MYC, CCND1, CCND2, CCND3, SOX2, SNAI2, BIRC2, BIRC3, ACTG1, ACTB, CTNNA3, CTNNA1, CTNNA2
## 153 VIP, CRH, CGA, LHB, GPHA2, GPHB5, TSHB, POMC, GCG, GIP, FSHB, NPPA, ADCYAP1, ADRB1, ADRB2, DRD1, DRD5, ADORA2A, HTR4, HTR6, PTGER2, ADCYAP1R1, VIPR2, CRHR1, CRHR2, LHCGR, TSHR, MC2R, GLP1R, GIPR, GPR119, FSHR, NPR1, GNAS, EDN1, EDN2, EDN3, SST, NPY, GHRL, OXT, HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, CHRM1, CHRM2, DRD2, GABBR1, GABBR2, ADORA1, EDNRA, NPY1R, SSTR1, SSTR2, SSTR5, HCAR1, HCAR2, HCAR3, FFAR2, SUCNR1, PTGER3, OXTR, GHSR, GNAI1, GNAI3, GNAI2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, ADCY10, HCN2, HCN4, CNGA1, CNGA2, CNGA3, CNGA4, CNGB1, CNGB3, CALML3, CALM2, CALM3, CALM1, CALML6, CALML5, CALML4, CAMK2A, CAMK2D, CAMK2B, CAMK2G, CAMK4, ABCC4, RAPGEF3, RAPGEF4, RRAS, RRAS2, PLD1, PLD2, PLCE1, MAPK8, MAPK10, MAPK9, RAP1A, RAP1B, TIAM1, VAV3, VAV1, VAV2, RAC1, RAC2, RAC3, PAK1, ARAP3, RHOA, AFDN, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, BRAF, RAF1, MAP2K1, MAP2K2, MAPK1, MAPK3, PRKACA, PRKACB, PRKACG, PPP1R1B, PPP1CA, PPP1CB, PPP1CC, CREB1, CREB3, CREB3L1, CREB3L2, CREB3L3, CREB3L4, CREB5, CREBBP, EP300, BDNF, FOS, JUN, GLI3, GLI1, PTCH1, HHIP, NFKBIA, NFKB1, RELA, SOX9, AMH, PPARA, ACOX3, ACOX1, NFATC1, F2R, BAD, LIPE, ROCK1, ROCK2, PPP1R12A, MYL9, TNNI3, PLN, ATP2A1, ATP2A3, ATP2A2, RYR2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, GRIA1, GRIA2, GRIA3, GRIA4, CFTR, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B4, ATP1B1, ATP1B2, ATP1B3, FXYD2, FXYD1, SLC9A1, ORAI1, ATP2B1, ATP2B3, ATP2B4, ATP2B2, CACNA1C, CACNA1D, CACNA1F, CACNA1S, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE10A
## 158 JAM3, ITGAM, ITGB2, JAM2, ITGA4, ITGB1, PECAM1, CD99, CD99L2, ITGAL, F11R, CDH5, CLDN4, CLDN3, CLDN7, CLDN19, CLDN16, CLDN14, CLDN15, CLDN17, CLDN20, CLDN11, CLDN18, CLDN22, CLDN5, CLDN10, CLDN8, CLDN6, CLDN2, CLDN1, CLDN9, CLDN23, CLDN34, CLDN25, CLDN24, OCLN, ESAM, VCAM1, EZR, MSN, ACTG1, ACTB, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, RAC1, CYBB, CYBA, NCF2, NCF1, NCF4, CTNNB1, CTNND1, CTNNA3, CTNNA1, CTNNA2, PTPN11, MMP2, MMP9, MAPK11, MAPK12, MAPK13, MAPK14, ICAM1, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, PTK2, PXN, BCAR1, THY1, ARHGAP35, ARHGAP5, RHOA, ROCK1, ROCK2, MYL2, MYL5, MYL7, MYL9, MYL10, MYL12B, MYL12A, MYL11, AFDN, RAP1A, RAP1B, SIPA1, VASP, ACTN1, ACTN4, VCL, CXCL12, CXCR4, GNAI1, GNAI3, GNAI2, RAPGEF3, RAPGEF4, RASSF5, PTK2B, ITK, TXK, VAV3, VAV1, VAV2, RAC2, CDC42, RHOH
## 161 TSHB, CGA, TSHR, ADRB1, ADRB2, ADRB3, GNAS, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, PRKACA, PRKACB, PRKACG, NPPA, NPR1, PRKG1, PRKG2, PLIN1, CIDEC, LIPE, PNPLA2, ABHD5, MGLL, FABP4, AQP7, AQP7B, INS, INSR, IRS1, IRS2, IRS4, PIK3CA, PIK3CD, PIK3CB, PIK3R1, PIK3R2, PIK3R3, AKT1, AKT2, AKT3, PDE3B, PLAAT3, PLAAT2, PTGS1, PTGS2, ADORA1, PTGER3, NPY, NPY1R, GNAI1, GNAI3, GNAI2
## 164 MRPS2, MRPS5, MRPS6, MRPS7, MRPS9, MRPS10, MRPS11, MRPS12, MRPS14, MRPS15, MRPS16, MRPS17, MRPS18C, MRPS18A, MRPS21, RPS2, RPS3, RPS3A, RPS4Y1, RPS4X, RPS4Y2, RPS5, RPS6, RPS7, RPS8, RPS9, RPS10, RPS10-NUDT3, RPS11, RPS12, RPS13, RPS14, RPS15, RPS15A, RPS16, RPS17, RPS18, RPS19, RPS20, RPS21, RPS23, RPS24, RPS25, RPS26, RPS27, RPS27L, RPS27A, RPS28, RPS29, FAU, RPSA, MRPL1, MRPL2, MRPL3, MRPL4, MRPL12, MRPL9, MRPL10, MRPL11, MRPL13, MRPL14, MRPL15, MRPL16, MRPL17, MRPL18, MRPL19, MRPL20, MRPL21, MRPL22, MRPL23, MRPL24, MRPL27, MRPL28, MRPL30, MRPL32, MRPL33, MRPL34, MRPL35, MRPL36, RPL3L, RPL3, RPL4, RPL5, RPL6, RPL7, RPL7A, RPL8, RPL9, RPL10L, RPL10, RPL10A, RPL11, RPL12, RPL13, RPL13A, RPL14, RPL15, RPL17, RPL17-C18orf32, RPL18, RPL18A, RPL19, RPL21, RPL22L1, RPL22, RPL23, RPL23A, RSL24D1, RPL24, RPL26, RPL26L1, RPL27, RPL27A, RPL28, RPL29, RPL30, RPL31, RPL32, RPL34, RPL35, RPL35A, RPL36, RPL37, RPL37A, RPL38, RPL39, UBA52, RPL41, RPL36AL, RPL36A, RPL36A-HNRNPH2, RPLP0, RPLP1, RPLP2, RNA18SN1, RNA18SN4, RNA18SN5, RNA18SN2, RNA18SN3, RNA28SN5, RNA28SN2, RNA28SN4, RNA28SN3, RNA28SN1, RNA5S1, RNA5S16, RNA5S6, RNA5S11, RNA5S5, RNA5S13, RNA5S4, RNA5S3, RNA5S2, RNA5S10, RNA5S12, RNA5S8, RNA5S7, RNA5S14, RNA5S15, RNA5S17, RNA5S9, RNA5-8SN5, RNA5-8SN1, RNA5-8SN2, RNA5-8SN3, RNA5-8SN4
## 165 SCNN1A, SCNN1B, SCNN1G, ENTPD2, TAS1R2, TAS1R3, GNAT3, GNB3, GNG13, ADCY4, ADCY6, ADCY8, PRKACA, PRKACB, PRKACG, PLCB1, PLCB2, PLCB3, PLCB4, ITPR3, TRPM5, SCN2A, SCN3A, SCN9A, CALHM1, P2RX2, P2RX3, P2RY1, P2RY4, CHRM3, TAS1R1, GRM1, GRM4, TAS2R39, TAS2R40, TAS2R41, TAS2R43, TAS2R31, TAS2R45, TAS2R46, TAS2R19, TAS2R20, TAS2R50, TAS2R60, TAS2R42, TAS2R3, TAS2R4, TAS2R16, TAS2R1, TAS2R9, TAS2R8, TAS2R7, TAS2R13, TAS2R10, TAS2R14, TAS2R5, TAS2R38, TAS2R30, PDE1A, PDE1B, PDE1C, PKD2L1, PKD1L3, KCNK5, HCN4, CACNA1A, CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABBR1, GABBR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR3A, HTR3E, HTR3D, HTR3C, HTR3B, ASIC2
## 167 KITLG, IL7, IL4, CSF2, FLT3LG, IL5, CSF3, IL3, IL6, IL11, IL1A, IL1B, TNF, CSF1, EPO, THPO, CD34, FLT3, DNTT, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, CD44, KIT, IL2RA, IL7R, TFRC, CD38, CD7, CD2, CD5, CD1A, CD1B, CD1C, CD1D, CD1E, CD4, CD8A, CD8B, CD8B2, CD3D, CD3E, CD3G, MME, CD9, CD19, CD22, CD24, MS4A1, CR2, CD37, IGH, FCER2, CR1, CR1L, CSF2RA, IL3RA, CD33, IL4R, IL6R, FCGR1A, CSF1R, ANPEP, ITGAM, CD14, IL9R, IL1R1, IL1R2, CSF3R, IL5RA, EPOR, CD36, GYPA, CD55, CD59, IL11RA, ITGB3, ITGA2B, GP9, GP1BA, GP1BB, GP5, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA6
## 168 RUNX1, CSF1R, MPO, CSF2, IL3, RUNX1T1, HDAC1, HDAC2, SIN3A, NCOR1, CEBPA, PER2, SPI1, CD14, ITGAM, FCGR1A, JUP, PML, RARA, CCNA2, CCNA1, CEBPE, BCL2A1, ZBTB16, MYC, DUSP6, TCF3, PBX1, WNT16, ETV6, ETV7, DEFA1, DEFA3, DEFA4, DEFA5, DEFA6, DEFA1B, ELANE, GZMB, KMT2A, AFF1, CDK9, CCNT1, CCNT2, MLLT1, MLLT3, DOT1L, LMO2, PBX3, RUNX2, SMAD1, KLF3, MEF2C, HOXA9, HOXA10, JMJD1C, HMGA2, KDM6A, SUPT3H, PROM1, FLT3, BMP2K, IGF1R, CDKN1B, CDK14, MEIS1, HOXA11, SIX1, SIX4, EYA1, CDKN2C, HPGD, GRIA3, FUT8, TLX3, TLX1, BCL11B, LDB1, LYL1, HHEX, PTCRA, REL, CCND2, BIRC2, BIRC3, TRAF1, BCL2L1, CD86, CD40, BCL6, IGH, MAF, ITGB7, NSD2, H3-5, H3-3B, H3C4, H3C3, H3C1, H3-3A, H3-4, H3C14, H3C15, H3C13, H3C6, H3C11, H3C8, H3C12, H3C10, H3C2, H3C7, PAX5, PAX8, PPARG, RXRA, RXRB, RXRG, PRCC, TFE3, CDKN1A, TMPRSS2, ERG, PLAU, PLAT, MMP3, MMP9, ZEB1, IL1R2, SPINT1, ETV1, ETV4, ETV5, SLC45A3, ELK4, DDX5, MYCN, MAX, MDM2, PTK2, TP53, BMI1, COMMD3-BMI1, SP1, ZBTB17, NTRK1, NGFR, MEN1, EWSR1, FLI1, IGF1, ID2, TGFBR2, IGFBP3, FEV, ATF1, ARNT2, ATM, MITF, WT1, PDGFA, IL2RB, BAIAP3, TSPAN7, MLF1, NR4A3, TAF15, FUS, DDIT3, CEBPB, IL6, NFKBIZ, NFKB1, RELA, CXCL8, PAX7, PAX3, FOXO1, FLT1, SS18L1, SS18, SSX1, SSX2, SSX2B, NUPR1, ASPSCR1, MET, GADD45A, GADD45B, GADD45G, BAX, BAK1, DDB2, POLK
## num_genes_in_path num_up_reg_genes_in_path num_down_reg_genes_in_path
## 1 266 51 25
## 2 273 50 27
## 8 155 30 19
## 9 148 14 15
## 12 232 34 25
## 14 134 24 15
## 18 203 21 25
## 21 223 28 26
## 3 131 24 12
## 4 46 19 2
## 15 143 26 10
## 5 127 43 11
## 7 131 23 9
## 11 102 18 10
## 24 142 19 7
## 6 73 17 7
## 10 73 13 10
## 13 97 9 13
## 16 128 13 11
## 23 58 7 8
## 17 166 10 17
## 19 236 20 26
## 39 294 27 22
## 58 210 15 22
## 20 89 10 12
## 25 108 12 11
## 27 121 21 13
## 29 107 11 14
## 46 137 15 17
## 47 62 7 4
## 61 142 17 17
## 71 69 11 6
## 22 222 32 24
## 65 203 17 19
## 26 75 7 4
## 147 43 7 4
## 28 249 35 26
## 49 247 21 31
## 57 137 16 20
## 74 197 18 18
## 30 112 12 19
## 31 212 19 26
## 37 225 11 28
## 45 127 11 14
## 52 215 17 22
## 73 194 12 21
## 85 136 16 13
## 32 104 8 17
## 33 132 10 12
## 55 129 4 15
## 56 75 4 9
## 60 150 9 13
## 64 120 7 14
## 68 86 3 9
## 76 113 6 10
## 82 98 3 8
## 95 106 7 9
## 101 137 4 12
## 111 65 2 9
## 121 64 4 7
## 133 167 8 18
## 34 157 17 15
## 40 162 19 18
## 42 139 14 18
## 43 202 26 25
## 53 92 18 9
## 135 171 9 17
## 35 102 8 12
## 50 112 10 10
## 70 104 6 13
## 83 180 13 14
## 86 232 10 16
## 99 77 5 5
## 112 76 6 6
## 130 104 8 12
## 36 121 8 16
## 160 189 9 13
## 38 119 6 15
## 63 93 5 9
## 98 98 4 12
## 41 70 9 8
## 48 184 9 19
## 54 94 8 14
## 44 36 4 4
## 51 119 14 19
## 59 139 14 11
## 127 154 11 7
## 62 97 11 7
## 75 68 4 10
## 79 76 10 8
## 81 70 7 8
## 89 72 5 7
## 100 85 5 10
## 102 59 4 8
## 106 67 6 8
## 108 72 7 5
## 113 76 7 8
## 115 75 5 7
## 119 86 7 5
## 128 98 5 9
## 131 58 4 3
## 134 81 5 10
## 140 69 5 4
## 146 97 6 12
## 166 131 5 9
## 66 192 7 27
## 67 100 10 12
## 69 229 19 21
## 155 201 15 15
## 72 205 16 20
## 91 101 5 9
## 107 143 11 14
## 109 147 16 17
## 110 149 15 11
## 120 155 16 16
## 150 155 20 17
## 154 168 21 16
## 77 141 24 17
## 78 212 13 24
## 80 70 4 8
## 142 109 7 10
## 163 47 3 5
## 84 72 9 15
## 87 156 22 16
## 88 89 4 14
## 96 92 3 16
## 103 104 7 15
## 132 108 3 12
## 90 124 9 19
## 92 49 3 4
## 116 69 3 5
## 145 186 9 12
## 93 69 2 11
## 97 97 2 9
## 122 114 1 6
## 124 67 2 7
## 129 92 1 9
## 139 88 5 7
## 141 60 2 5
## 149 113 4 8
## 151 76 1 5
## 157 134 4 10
## 94 240 16 19
## 104 139 16 16
## 105 41 3 4
## 159 37 4 1
## 114 159 11 15
## 117 32 5 3
## 118 148 8 11
## 123 169 18 14
## 125 95 13 7
## 126 251 19 12
## 136 87 7 5
## 137 182 14 13
## 138 65 1 7
## 143 34 10 1
## 156 90 7 5
## 144 70 5 6
## 152 50 3 2
## 148 170 14 19
## 162 157 17 13
## 153 221 10 13
## 158 114 2 11
## 161 58 2 7
## 164 166 1 2
## 165 86 2 5
## 167 99 6 9
## 168 193 13 7
## percent_up_or_down_genes_pathway Cluster Status
## 1 0.28571429 1 Representative
## 2 0.28205128 1 Member
## 8 0.31612903 1 Member
## 9 0.19594595 1 Member
## 12 0.25431034 1 Member
## 14 0.29104478 1 Member
## 18 0.22660099 1 Member
## 21 0.24215247 1 Member
## 3 0.27480916 2 Representative
## 4 0.45652174 3 Representative
## 15 0.25174825 3 Member
## 5 0.42519685 4 Representative
## 7 0.24427481 4 Member
## 11 0.27450980 4 Member
## 24 0.18309859 4 Member
## 6 0.32876712 5 Representative
## 10 0.31506849 6 Representative
## 13 0.22680412 6 Member
## 16 0.18750000 7 Representative
## 23 0.25862069 7 Member
## 17 0.16265060 8 Representative
## 19 0.19491525 9 Representative
## 39 0.16666667 9 Member
## 58 0.17619048 9 Member
## 20 0.24719101 10 Representative
## 25 0.21296296 10 Member
## 27 0.28099174 10 Member
## 29 0.23364486 10 Member
## 46 0.23357664 10 Member
## 47 0.17741935 10 Member
## 61 0.23943662 10 Member
## 71 0.24637681 10 Member
## 22 0.25225225 11 Representative
## 65 0.17733990 11 Member
## 26 0.14666667 12 Representative
## 147 0.25581395 12 Member
## 28 0.24497992 13 Representative
## 49 0.21052632 13 Member
## 57 0.26277372 13 Member
## 74 0.18274112 13 Member
## 30 0.27678571 14 Representative
## 31 0.21226415 14 Member
## 37 0.17333333 14 Member
## 45 0.19685039 14 Member
## 52 0.18139535 14 Member
## 73 0.17010309 14 Member
## 85 0.21323529 14 Member
## 32 0.24038462 15 Representative
## 33 0.16666667 16 Representative
## 55 0.14728682 16 Member
## 56 0.17333333 16 Member
## 60 0.14666667 16 Member
## 64 0.17500000 16 Member
## 68 0.13953488 16 Member
## 76 0.14159292 16 Member
## 82 0.11224490 16 Member
## 95 0.15094340 16 Member
## 101 0.11678832 16 Member
## 111 0.16923077 16 Member
## 121 0.17187500 16 Member
## 133 0.15568862 16 Member
## 34 0.20382166 17 Representative
## 40 0.22839506 17 Member
## 42 0.23021583 17 Member
## 43 0.25247525 17 Member
## 53 0.29347826 17 Member
## 135 0.15204678 17 Member
## 35 0.19607843 18 Representative
## 50 0.17857143 18 Member
## 70 0.18269231 18 Member
## 83 0.15000000 18 Member
## 86 0.11206897 18 Member
## 99 0.12987013 18 Member
## 112 0.15789474 18 Member
## 130 0.19230769 18 Member
## 36 0.19834711 19 Representative
## 160 0.11640212 19 Member
## 38 0.17647059 20 Representative
## 63 0.15053763 20 Member
## 98 0.16326531 20 Member
## 41 0.24285714 21 Representative
## 48 0.15217391 21 Member
## 54 0.23404255 21 Member
## 44 0.22222222 22 Representative
## 51 0.27731092 23 Representative
## 59 0.17985612 24 Representative
## 127 0.11688312 24 Member
## 62 0.18556701 25 Representative
## 75 0.20588235 25 Member
## 79 0.23684211 25 Member
## 81 0.21428571 25 Member
## 89 0.16666667 25 Member
## 100 0.17647059 25 Member
## 102 0.20338983 25 Member
## 106 0.20895522 25 Member
## 108 0.16666667 25 Member
## 113 0.19736842 25 Member
## 115 0.16000000 25 Member
## 119 0.13953488 25 Member
## 128 0.14285714 25 Member
## 131 0.12068966 25 Member
## 134 0.18518519 25 Member
## 140 0.13043478 25 Member
## 146 0.18556701 25 Member
## 166 0.10687023 25 Member
## 66 0.17708333 26 Representative
## 67 0.22000000 27 Representative
## 69 0.17467249 28 Representative
## 155 0.14925373 28 Member
## 72 0.17560976 29 Representative
## 91 0.13861386 29 Member
## 107 0.17482517 29 Member
## 109 0.22448980 29 Member
## 110 0.17449664 29 Member
## 120 0.20645161 29 Member
## 150 0.23870968 29 Member
## 154 0.22023810 29 Member
## 77 0.29078014 30 Representative
## 78 0.17452830 31 Representative
## 80 0.17142857 32 Representative
## 142 0.15596330 32 Member
## 163 0.17021277 32 Member
## 84 0.33333333 33 Representative
## 87 0.24358974 34 Representative
## 88 0.20224719 35 Representative
## 96 0.20652174 35 Member
## 103 0.21153846 35 Member
## 132 0.13888889 35 Member
## 90 0.22580645 36 Representative
## 92 0.14285714 37 Representative
## 116 0.11594203 37 Member
## 145 0.11290323 37 Member
## 93 0.18840580 38 Representative
## 97 0.11340206 38 Member
## 122 0.06140351 38 Member
## 124 0.13432836 38 Member
## 129 0.10869565 38 Member
## 139 0.13636364 38 Member
## 141 0.11666667 38 Member
## 149 0.10619469 38 Member
## 151 0.07894737 38 Member
## 157 0.10447761 38 Member
## 94 0.14583333 39 Representative
## 104 0.23021583 40 Representative
## 105 0.17073171 41 Representative
## 159 0.13513514 41 Member
## 114 0.16352201 42 Representative
## 117 0.25000000 43 Representative
## 118 0.12837838 44 Representative
## 123 0.18934911 45 Representative
## 125 0.21052632 46 Representative
## 126 0.12350598 47 Representative
## 136 0.13793103 48 Representative
## 137 0.14835165 49 Representative
## 138 0.12307692 50 Representative
## 143 0.32352941 51 Representative
## 156 0.13333333 51 Member
## 144 0.15714286 52 Representative
## 152 0.10000000 52 Member
## 148 0.19411765 53 Representative
## 162 0.19108280 53 Member
## 153 0.10407240 54 Representative
## 158 0.11403509 55 Representative
## 161 0.15517241 56 Representative
## 164 0.01807229 57 Representative
## 165 0.08139535 58 Representative
## 167 0.15151515 59 Representative
## 168 0.10362694 60 Representativedev.off()## quartz_off_screen
## 2output_pin_clustered <- cluster_enriched_terms(output_df_pin, plot_dend = TRUE, plot_clusters_graph = TRUE)## The maximum average silhouette width was 0.14 for k = 60
selected_clusters <- subset(output_pin_clustered, Cluster %in% 1:5)
pdf(file = paste0(outdir,"/Enrichment_with_", pin, "_clusters_1-5.pdf"))
enrichment_chart(selected_clusters, plot_by_cluster = TRUE)## Plotting the enrichment bubble chartdev.off()## quartz_off_screen
## 2enrichment_chart(selected_clusters, plot_by_cluster = TRUE)## Plotting the enrichment bubble chart
selected_clusters <- subset(output_pin_clustered, Cluster %in% 6:10)
pdf(file = paste0(outdir,"/Enrichment_with_", pin, "_clusters_6-10.pdf"))
enrichment_chart(selected_clusters, plot_by_cluster = TRUE)## Plotting the enrichment bubble chartdev.off()## quartz_off_screen
## 2enrichment_chart(selected_clusters, plot_by_cluster = TRUE)## Plotting the enrichment bubble chart
Make heatmap of enriched pathways vs differentially expressed genes
pdf(file = paste0(outdir,"/Enrichment_heatmap_", pin, "_up_or_down_10_terms.pdf"))
term_gene_heatmap(result_df = output_df_pin, num_terms = 10)
dev.off()## quartz_off_screen
## 2#pdf(file = paste0(outdir,"/Enrichment_heatmap_", pin, "_fold_change_10_terms.pdf"))
#term_gene_heatmap(result_df = output_df_pin, genes_df = datPF, num_terms = 10)
#dev.off()
term_gene_heatmap(result_df = output_df_pin, num_terms = 10)
#term_gene_heatmap(result_df = output_df_pin, genes_df = datPF, num_terms = 10)Term gene graph of top enriched terms.
pdf(file=paste0(outdir,"/Enrichment_Term-Gene_Graph_", pin, "_top_5_terms.pdf"), width=11, height=8.5)
term_gene_graph(result_df = output_df_pin, use_description = TRUE, num_terms = 5)
dev.off()## quartz_off_screen
## 2term_gene_graph(result_df = output_df_pin, use_description = TRUE, num_terms = 3)
pdf(file=paste0(outdir,"/Enrichment_Term-Gene_Graph_", pin, "_top_10_terms.pdf"), width=11, height=8.5)
term_gene_graph(result_df = output_df_pin, use_description = TRUE, num_terms = 10)
dev.off()## quartz_off_screen
## 2term_gene_graph(result_df = output_df_pin, use_description = TRUE, num_terms = 10)## Warning: ggrepel: 43 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
Make an UpSet heatmap of enriched pathways vs differentially expressed genes
pdf(file = paste0(outdir,"/Enrichment_UpSet_plot_", pin, "_up_or_down_10_terms.pdf"))
UpSet_plot(result_df = output_df_pin)
dev.off()## quartz_off_screen
## 2pdf(file = paste0(outdir,"/Enrichment_UpSet_plot_", pin, "_fold_change_10_terms.pdf"))
UpSet_plot(result_df = output_df_pin, genes_df = datPF, num_terms = 10)## ## Processing input. Converting gene symbols,
## if necessary (and if human gene symbols provided)## Number of genes provided in input: 10881## Number of genes in input after p-value filtering: 10881## pathfindR cannot handle p values < 1e-13. These were changed to 1e-13## Could not find any interactions for 7105 (65.3%) genes in the PIN## Final number of genes in input: 3776dev.off()## quartz_off_screen
## 2UpSet_plot(result_df = output_df_pin)
UpSet_plot(result_df = output_df_pin, genes_df = datPF, num_terms = 10)## ## Processing input. Converting gene symbols,
## if necessary (and if human gene symbols provided)## Number of genes provided in input: 10881## Number of genes in input after p-value filtering: 10881## pathfindR cannot handle p values < 1e-13. These were changed to 1e-13## Could not find any interactions for 7105 (65.3%) genes in the PIN## Final number of genes in input: 3776
# make a score matrix of enriched pathways by sample.
“calculate the agglomerated z score of each enriched term per sample. This allows the user to individually examine the scores and infer how a term is overall altered (activated or repressed) in a given sample or a group of samples.”
representative_df <- output_pin_clustered[output_pin_clustered$Status == "Representative", ]
representative_df <- as.data.frame(representative_df)
dat.m <- as.matrix(dat)
pdf(file=paste0(outdir,"/Enrichment_Score_Matrix_rep_terms_", pin, "_by_sample.pdf"))
score_matrix <- score_terms(
enrichment_table = representative_df,
exp_mat = dat.m,
cases = cases,
use_description = TRUE, # default FALSE
label_samples = TRUE, # default = TRUE
#case_title = "R", # default = "Case"
#control_title = "", # default = "Control",
low = "#f7797d", # default = "green"
mid = "#fffde4", # default = "black"
high = "#1f4037" # default = "red"
)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)dev.off()## quartz_off_screen
## 2pdf(file=paste0(outdir,"/Enrichment_Score_Matrix_all_terms_", pin, "_by_sample.pdf"))
score_matrix <- score_terms(
enrichment_table = output_pin_clustered,
exp_mat = dat.m,
cases=cases,
use_description = TRUE, # default FALSE
label_samples = TRUE, # default = TRUE
#case_title = "RA", # default = "Case"
#control_title = "Healthy", # default = "Control"
low = "#f7797d", # default = "green"
mid = "#fffde4", # default = "black"
high = "#1f4037" # default = "red"
)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)dev.off()## quartz_off_screen
## 2score_matrix <- score_terms(
enrichment_table = representative_df,
exp_mat = dat.m,
cases = cases,
use_description = TRUE, # default FALSE
label_samples = TRUE, # default = TRUE
#case_title = "R", # default = "Case"
#control_title = "", # default = "Control",
low = "#f7797d", # default = "green"
mid = "#fffde4", # default = "black"
high = "#1f4037" # default = "red"
)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
score_matrix <- score_terms(
enrichment_table = output_pin_clustered,
exp_mat = dat.m,
cases=cases,
use_description = TRUE, # default FALSE
label_samples = TRUE, # default = TRUE
#case_title = "RA", # default = "Case"
#control_title = "Healthy", # default = "Control"
low = "#f7797d", # default = "green"
mid = "#fffde4", # default = "black"
high = "#1f4037" # default = "red"
)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(all_scores_matrix, current_term_scores): number of columns of
## result is not a multiple of vector length (arg 2)## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
## Warning in rbind(current_term_score_matrix, gene_scores): number of columns of
## result is not a multiple of vector length (arg 2)
Save data!
write.csv(output_pin_clustered, file=paste0(outdir,"/PathfindR_output_", pin, ".csv"))